Cocos nucifera (Koko) : medicinal properties in alcoholic extraction

Cocos nucifera (Koko, Coco) — family Arecacées.

Scientific synonyms : Calappa nucifera-(L)-Kuntze, Cocos indica-Royle, C nana-Griff, Palma cocos-Mill.

Recognised external sources linked to this monograph: TRAMIL.

This database documents alcoholic (ethanol) extractions of active substances. Our monograph currently lists 15 indications in alcoholic extraction for this species. The Lapo v2 catalogue records 143 scientific references for this species (full detail in the application).

Important — scientific references on this public page: only a short excerpt of each cited source is shown (selected abstract sentences), kept in the original language of the publication (most often English), without translation. These excerpts are not the full article text and are not a complete bibliography. The full reference records and complete monographic detail are available in the Lapo v2 application (free 30-day trial).

1. 1

   Type II diabetes mellitus

   Plant part used: Inflorescence.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to KAUR G (2017)

     Excerpt C.nucifera inflorescence (CnI) has been reported in the literature to be useful in the treatment of diarrhoea, dysentery, diabetes, & dyspepsia. Objective: To evaluate antidiabetic activity of CnI in combination with metformin in Streptozotocin (STZ) induced diabetic rats.

   • According to Emojevwe V (2018)

     Excerpt The Anti-diabetic effects of Cocos Nucifera (Coconut) Husk were studied on 21 alloxan-induced diabetic rats which were randomly grouped into three (n=7). It was therefore concluded that CN husk tea has a significant hypoglycemic & anti-diabetic effects in alloxan-induced diabetes.

   • According to Renjith RS (2012)

     Excerpt Renjith RS et al, Young inflorescence of Cocos nucifera contributes to improvement of glucose homeostasis & antioxidant status in diabetic rats.

   • According to Saranya S (2014)

     Excerpt The present study is aimed to evaluate the antidiabetic & antioxidant nature of Cocos nucifera flowers extract in STZ induced diabetic rats. Oral administration of CN flower extract (300 mg/kg b.w/day) to diabetic rats for 30 days significantly reduced the levels of blood glucose, glycosylated hemoglobin, urea, uric acid & creatinine.

   • According to Kabra MP (2012)

     Excerpt Cocos nucifera flower extract (CNFE) & coconut oil (CO) at a dose of 300 mg/kg body weight for 15 days, suppressed the elevated blood glucose and lipid levels in alloxan induce diabetic rats. The ethanolic extract of C nucifera flowers & fruit oil was administered orally at a dose level of 300mg/kg body weight and compared their effect with Glibenclamide for chronic study (15 days).

2. 2

   Cancer: chemoprevention

   Plant part used: Fruit.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to Dev S (2017)

     Excerpt This study revealed the antioxidant & anticancer activities of the ethanolic extract of the tender fruits of Cocos nucifera. In DMBA and croton oil-induced skin cancer in model mice, the extract significantly decreased the number, size, yield and burden of tumor when compared with carcinogenic control.

   • According to Khonkarn R (2010)

     Excerpt We concluded that the EA fraction of rambutan peel is a promising resource for potential novel antioxidant agents whereas the hexane fraction of coconut peel may contain novel anticancer compounds.

   • According to Koscheck PR (2007)

     Excerpt Koscheck PR et al, the husk fiber of Cocos nucifera L.

   • According to HEENATAJ B (2017)

     Excerpt It is well known for its effective properties such as antitumor antioxidant, antimicrobial, antidotal, Antiseptic, Bactericidal, etc.

   • According to Lima EBC (2015)

     Excerpt nucifera have some biological effects, such as antihelminthic, anti-inflammatory, antinociceptive, antioxidant, antifungal, antimicrobial, & antitumor activities. Cocos nucifera (L.) (Arecaceae) is commonly called the “coconut tree” & is the most naturally widespread fruit plant on Earth.

3. 3

   Rheumatism, osteoarthritis, arthritis, oedema

   Plant part used: Fruit.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to Zakaria ZA (2006)

     Excerpt nucifera as antipyretic, anti-inflammatory & wound healing agents. The fresh juice & aqueous kernel extract of C.N exhibited significant (p<0.05) anti-inflammatory & antipyretic activities & promote wound healing with the latter producing a more effective effects in all assays used.

   • According to Ilegbedion GI (2013)

     Excerpt Ilegbedion GI et al, ANTI-INFLAMMATORY ACTIVITY OF COCOS NUCIFERA WATER & OIL, Pacific J of Med Sci, 11: 2, 2013,.

   • According to Dua K (2013)

     Excerpt Dua K et al, Antiinflammatory, antibacterial and analgesic potential of Cocos nucifera L: A review.

   • According to Anosike CA (2010)

     Excerpt From the results obtained, rats treated with 100 and 200mg/kg of the extract showed significant reduction of oedema at the later phase of inflammation and also reduced the ulcer induced by indomethacin, with 100mg/kg and 200mg/kg doses having an ulcer inhibition of 65.4% and 67.9% respectively; 400mg/kg of the extract increased the paw oedema of the animals & also evinced an increase in ulcération when compared to control. This suggests that the extract at low doses has potential anti-inflammatory & antiulcerogenic effect.

   • According to Lima EBC (2015)

     Excerpt nucifera have some biological effects, such as antihelminthic, anti-inflammatory, antinociceptive, antioxidant, antifungal, antimicrobial, & antitumor activities. In addition, other properties such as antihypertensive, anti-inflammatory, antimicrobial, antioxidant, cardioprotective, antiseizure, cytotoxicity, hepatoprotective, vasodilation, nephroprotective, & anti-osteoporosis effects were also reported.

Further indications (including other extraction modes where applicable), dosages, precautions for use, and the <strong>full scientific references</strong> (complete records, not only the short excerpts above) are available in the complete monographic record in the Lapo v2 application.