Cuphra ignea (Z§b-sigaràt) : medicinal properties in alcoholic extraction

Cuphra ignea (Z§b-sigaràt, Herb cigarette, Herbe cigarette) — family Lythracées.

Scientific synonyms : Cuphea liebmannii Koehne, Parsonsia ignea (A. DC.) Standl, P liebmannii (Koehne) Standl, P watsonii--(ME Jones).

This database documents alcoholic (ethanol) extractions of active substances. Our monograph currently lists 5 indications in alcoholic extraction for this species. The Lapo v2 catalogue records 7 scientific references for this species (full detail in the application).

Important — scientific references on this public page: only a short excerpt of each cited source is shown (selected abstract sentences), kept in the original language of the publication (most often English), without translation. These excerpts are not the full article text and are not a complete bibliography. The full reference records and complete monographic detail are available in the Lapo v2 application (free 30-day trial).

1. 1

   Cancer: adjuvant treatment for lung cancer

   Plant part used: Aerial parts.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to Hassan SK (2019)

     Excerpt Thus, the objective of current work was to ascertain the possible preventive & therapeutic efficacies of Cuphea ignea extract in a mouse model of lung tumorigenesis & its cytotoxicity toward the A549 human lung cancer cell line. The results revealed that the oral administration of benzo(a)pyrene resulted in increases in relative lung weight, serum levels of tumor markers (ADA, AHH, & LDH), & the inflammatory marker NF-κB, & a decreased total antioxidant capacity compared with the control.

2. 2

   Dyspepsia, gastric ulcer

   Plant part used: Aerial parts.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to Mousa AM (2019)

     Excerpt Therefore, the present study was performed to evaluate the gastroprotective effect of aqueous ethanolic extract of CI aerial parts on ethanol-induced gastric ulcer. ignea aerial parts extract at doses of 250 & 500 mg/kg body weight & Ranitidine (a reference drug) at a dose of 30 mg/kg body weight were orally administrated daily for 7 days before ulcer induction.

3. 3

   Hypertension, vasoconstriction

   Plant part used: Sheet.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to El-Kot WMI (2020)

     Excerpt The results showed its potential to decrease the blood pressure & to restore the changes in ACE & nitric oxide levels in addition to the oxidative stress parameters in L-NAME-induced hypertensive rats. CI can be used as a complementary treatment in hypertension & other cardiovascular complications.

   • According to Ismail WM (2020)

     Excerpt The aim of this research was to study the antihypertensive activity of the plant by applying a bio-guided fractionation scheme of the leaves, stems, & flowers using in vitro angiotensin-converting enzyme (ACE) & renin inhibition assays to identify the active organ & its respective active fractions. Some Cuphea members are traditionally used in treatment of hypertension.

   • According to Ismail WM (2022)

     Excerpt The results revealed that the ethanolic extract of the leaves in two doses (250 & 500 mg/kg b.wt.) significantly normalized the elevated systolic blood pressure in N(G)-nitro-L-arginine-methyl ester-induced hypertension in rats. The aim of this study is to verify the in vivo antihypertensive potential of CI & to explore its metabolic profile using a UHPLC-Orbitrap-HRMS technique.

   • According to Mousa AM (2019)

     Excerpt One hour after ethanol administration blood samples were collected & then stomachs of sacrificed rats were subjected to biochemical, macroscopic & microscopic studies. ignea aerial parts extract at doses of 250 & 500 mg/kg body weight & Ranitidine (a reference drug) at a dose of 30 mg/kg body weight were orally administrated daily for 7 days before ulcer induction.

Further indications (including other extraction modes where applicable), dosages, precautions for use, and the <strong>full scientific references</strong> (complete records, not only the short excerpts above) are available in the complete monographic record in the Lapo v2 application.