Curcuma amada (Jenjanb-mango) : medicinal properties in alcoholic extraction

Curcuma amada (Jenjanb-mango, Gingembre Mangot) — family Zingiberacées.

Scientific synonyms : Curcuma amada var glabra Velay-Unnikr, Asha & Maya.

This database documents alcoholic (ethanol) extractions of active substances. Our monograph currently lists 18 indications in alcoholic extraction for this species. The Lapo v2 catalogue records 87 scientific references for this species (full detail in the application).

Important — scientific references on this public page: only a short excerpt of each cited source is shown (selected abstract sentences), kept in the original language of the publication (most often English), without translation. These excerpts are not the full article text and are not a complete bibliography. The full reference records and complete monographic detail are available in the Lapo v2 application (free 30-day trial).

1. 1

   Hepatitis, cirrhosis, fatty liver, normalisation of serum parameters

   Plant part used: Rhizome.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to Khan R (2020)

     Excerpt 50% ethanolic extract of C amada (CAE) (100 & 200mg/kg) hepatoprotective efficiency was examined against paracetamol (1000 mg/kg) induced hepatotoxicity, elevated hepatic enzymes alanine aminotransferase (ALT), aspartate aminotransferase (AST), & alkaline phosphatase (ALP), total bilirubin direct bilirubin content in the serum. rhizome of Curcuma amada are selected to allocate the hepatoprotective activity in scientifically approbate experimental models.

   • According to Ramnath V (1966)

     Excerpt The scope of this study is to evaluate the hepatoprotective efficacy of rhizome Curcuma Amada Roxb (CAR) in CCl4 induced hepatotoxicity in rats. The histological architecture of liver sections in Group-IV–VI showed more or less normal lobular pattern with mild degrees of fatty change, necrosis & lymphocyte infiltration almost comparable to those of control group.

   • According to Mitra D (2019)

     Excerpt Activities of glutamate oxaloacetate transaminase & glutamate pyruvate transaminase in liver were significantly recovered along with the correction of Bax & Bcl-2 gene expression in hepatic tissue after the extract treatment in diabetic rats in respect to untreated diabetic group. Curcuma amada is the most popular traditional medicine in India for the treatment of diabetes.

   • According to Ayati Z (2019)

     Excerpt Besides, pharmacological studies have indicated wide range of Curcuma's activities, such as hepato-protective, antifungal, antihypertensive & neuroprotective. Various species of Curcuma have long been used for several purposes such as healing wounds, liver disorders, jaundice & also as a blood purifier.

   • According to Shirsath SR (2017)

     Excerpt Curcumin, a dietary phytochemical, has been extracted from rhizomes of Curcuma amada using ultrasound assisted extraction (UAE) & the results compared with the conventional extraction approach to establish the process intensification benefits. The effect of operating parameters such as type of solvent, extraction time, extraction temperature, solid to solvent ratio, particle size & ultrasonic power on the extraction yield have been investigated in details for the approach UAE.

2. 2

   Cancer: adjuvant treatment for glioblastoma; multiforme

   Plant part used: Rhizome.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to Ankita J (2013)

     Excerpt Acetone, Methanol, Ethanol & aqueous extracts of the rhizomes of C amada were screened for their anticancer properties. Curcuma amada has been shown to possess anti-inflammatory, antioxidant & antitumor properties.

   • According to Palanisamy VD (2017)

     Excerpt To evaluate the antioxidant & chemotherapeutic potential of Curcuma amada Rhizome extract on benzo(a)pyrene (BaP) induced cervical carcinoma in Sprague Dawley rats. Antioxidants & the markers carcinoembryonic antigen (CEA), cancer antigens (CAs) 125, gamma glutamyl transferase (GTT) were assayed in serum and the tissue was used for analyzing tumor burden & sectioned for histopathological assays.10% tissue homogenate was estimated for antioxidants & membrane-bound enzymes.

   • According to Win NN (2017)

     Excerpt Four new labdane diterpenoids, 12β-hydroxy-15-norlabda-8(17),13(14)-dien-16-oic acid (1), (E)-15-ethoxy-15-methoxylabda-8(17),12-dien-16-al (2), (E)-15α-ethoxy-14α-hydroxylabda-8(17),12-dien-16-olide (3), & 15-ethoxy-12β-hydroxyl-abda-8(17),1 3(14)-dien-16,15-olide (4) were isolated from the methanol extract of Curcuma amada rhizomes collected in Myanmar, together with 13 known analogs. All of the isolates were evaluated for their antiproliferative activities against a small panel of five different human cancer cell lines (A549, human lung cancer; HeLa, human cervical cancer; MCF7, human breast cancer; PANC-1 & PSN-1, human pancreatic cancer).

   • According to Sutar J (2020)

     Excerpt amada have also possessed several pharmaceutical properties such as antimicrobial, anti-inflammatory, analgesic, anticancer, anti hyperglyceridemic, antioxidant activity etc. Therefore, the present study was conducted to the preliminary screening of the phytochemicals, quantitative phytochemicals analysis, & antioxidant activity of rhizome & leaf powder sample of C.

   • According to Annapurna A (2021)

     Excerpt The present work evaluated the phytochemical, antioxidant, antimitotic, & antiproliferative properties of aqueous methanolic extract from leaves of Curcuma amada & Curcuma karnatakensis. amada exhibited higher radical scavenging activity for DPPH (IC50= 127.70 ± 4.05 μg / mL), Ferrous ion chelation (IC50= 287.83 ± 6.38 μg / mL) & CUPRAC antioxidant potential value of 6.33 ± 0.06 mg Trolox equivalent (TE)/g DW.

3. 3

   Osteoarthritis, arthritis, rheumatism, oedema

   Plant part used: Rhizome.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to Majumbar AM (2004)

     Excerpt In our earlier studies, an ethanol extract of Curcuma amada rhizome was reported for anti-inflammatory activity. Each fractionated extract was screened for anti-inflammatory activity, & the most active fraction was purified by column chromatography.

   • According to Ankita J (2013)

     Excerpt Curcuma amada has been shown to possess anti-inflammatory, antioxidant & antitumor properties. Acetone, Methanol, Ethanol & aqueous extracts of the rhizomes of C amada were screened for their anticancer properties.

   • According to Sutar J (2020)

     Excerpt amada have also possessed several pharmaceutical properties such as antimicrobial, anti-inflammatory, analgesic, anticancer, anti hyperglyceridemic, antioxidant activity etc. Therefore, the present study was conducted to the preliminary screening of the phytochemicals, quantitative phytochemicals analysis, & antioxidant activity of rhizome & leaf powder sample of C.

   • According to Annapurna A (2021)

     Excerpt amada leaf extract showed higher anti-inflammatory properties than C. The present work evaluated the phytochemical, antioxidant, antimitotic, & antiproliferative properties of aqueous methanolic extract from leaves of Curcuma amada & Curcuma karnatakensis.

   • According to Mahadevi R (2020)

     Excerpt It is traditionally used to treat various diseases which includes anti-inflammatory, anti-bacterial, anti-cancer, anti-tubercular, anti -allergy, anthelmintic & antipyretic activities. Curcuma amada is one of the important species of Curcuma family having medicinal and biological properties.

Further indications (including other extraction modes where applicable), dosages, precautions for use, and the <strong>full scientific references</strong> (complete records, not only the short excerpts above) are available in the complete monographic record in the Lapo v2 application.