Curcuma longa (Tjitjima) : medicinal properties in alcoholic extraction

Curcuma longa (Tjitjima, Mandja, Coolie saffron, Turmeric, Safran-kouli, Curcuma, Safran-à-coolie) — family Zingiberacées.

Scientific synonyms : Amomum curcuma-Jacq, C domestica-V., Stissera curcuma-Raeusch.

Recognised external sources linked to this monograph: TRAMIL and French Pharmacopoeia.

This database documents alcoholic (ethanol) extractions of active substances. Our monograph currently lists 48 indications in alcoholic extraction for this species. The Lapo v2 catalogue records 235 scientific references for this species (full detail in the application).

Important — scientific references on this public page: only a short excerpt of each cited source is shown (selected abstract sentences), kept in the original language of the publication (most often English), without translation. These excerpts are not the full article text and are not a complete bibliography. The full reference records and complete monographic detail are available in the Lapo v2 application (free 30-day trial).

1. 1

   Cancer: adjuvant treatment of liver cancer, hormone-dependent and hormone-independent breast cancer, and uterine cancer

   Plant part used: leaf.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to Naama JH (2010)

     Excerpt The extract showed a considerable anticancer activity against the cell line of human hepato cellular liver Carcinoma. Curcumin [(1E, 6E)-1,7-bis (4-hydroxy-3-methoxyphenyl) hepta-1,6-diene-3,5dione] is the major yellow pigment extracted from turmeric, a commonly used spice, derived from the rhizome of the plant Curcuma longa.

   • According to Gull N (2023)

     Excerpt Curcumin, the active ingredient in the Curcuma longa plant, has gained widespread attention in recent years because of its multifunctional properties as an antioxidant, anti-inflammatory, antimicrobial, & anticancer agent. Among all forms of cancers, hepatocellular carcinoma (HCC) is the fifth most common cancer worldwide.

   • According to Abolfazli, S. (1987)

     Excerpt Liver fibrosis may progress to liver cirrhosis, liver failure, or hepatocellular carcinoma.

   • According to Ekowati H (2013)

     Excerpt Curcuma Xanthorrhiza, Curcuma longa & Zingiber officinale are commonly used as herbals in Indonesia & around the world. Measurements of parameters based on liver histopathology and the parameters of serum alanine amino transferase (ALT) and aspartate amino transferase (AST).

   • According to Salama S (2013)

     Excerpt Thus, this study evaluated mechanisms of the hepatoprotective activity of Curcuma longa rhizome ethanolic extract (CLRE) on thioacetamide-induced liver cirrhosis in rats. Results: Histopathology, immunohistochemistry and liver Biochemistry were significantly lower in the Curcuma longa-treated groups compared with controls.

2. 2

   Type II diabetes mellitus

   Plant part used: Rhizome. Mentioned synergistic association: Curcuma zedoaria.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to Kuroda M (2005)

     Excerpt rhizomes) EtOH extract significantly suppressed an increase in blood glucose level in type 2 diabetic KK-A(y) mice. The turmeric (Curcuma longa L.

   • According to Santosh Kumar J (2016)

     Excerpt Objectives: The present study was undertaken to evaluate the hypolipidemic effects of ethanolic extract of Rhizomes of Curcuma longa in Alloxan induced diabetic rats with high fat diet & compared with of Pioglitazone, which has Anti-diabetic & action. Santosh Kumar J et al, Comparative Study of Hypolipemic effects of Ethanolic extract of Rhizomes of Curcuma longa (TURMERIC) Versus Pioglitazone in Alloxan induced Diabetic Rats.

   • According to Margină D (2015)

     Excerpt The results of the present study may be translated into clinical practice & demonstrate that C longa extracts may be effective in both the prevention of diabetes mellitus & in attenuating the development of complications associated with the disease. The antioxidant effects of the C longa extracts exerted on the membranes of Jurkat cells were the most prominent under both normal & hyperglycemic conditions.

   • According to KAUSA MA (2025)

     Excerpt The present study investigates the therapeutic effects of an ethanolic polyherbal extract from Citrullus colocynthis (Bitter Apple), Curcuma longa (Turmeric), & Myristica fragrans (Nutmeg) using advanced in silico & analytical methods. Diabetic neuropathy is one of the severe complications of diabetes, which affects the quality of life in a patient & increases the risk of amputations & chronic wounds.

   • According to PATHOMWICHAIWAT T (2023)

     Excerpt : This study aims to comprehensively review the existing evidence & conduct analysis of updated randomized controlled trials (RCTs) of turmeric (Curcuma longa, CL) & its related bioactive compounds on glycemic & metabolic parameters in patients with type 2 diabetes (T2DM), prediabetes, & metabolic syndrome (MetS) together with a sub-group analysis of different CL preparation forms.

3. 3

   Liver disorders: hepatitis, cirrhosis, alcoholic fatty liver disease

   Plant part used: Rhizome.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to Salama S (2013)

     Excerpt Thus, this study evaluated mechanisms of the hepatoprotective activity of Curcuma longa rhizome ethanolic extract (CLRE) on thioacetamide-induced liver cirrhosis in rats. Results: Histopathology, immunohistochemistry and liver Biochemistry were significantly lower in the Curcuma longa-treated groups compared with controls.

   • According to Naama JH (2010)

     Excerpt Curcumin [(1E, 6E)-1,7-bis (4-hydroxy-3-methoxyphenyl) hepta-1,6-diene-3,5dione] is the major yellow pigment extracted from turmeric, a commonly used spice, derived from the rhizome of the plant Curcuma longa. The extract showed a considerable anticancer activity against the cell line of human hepato cellular liver Carcinoma.

   • According to Ekowati H (2013)

     Excerpt Curcuma Xanthorrhiza, Curcuma longa & Zingiber officinale are commonly used as herbals in Indonesia & around the world. Measurements of parameters based on liver histopathology and the parameters of serum alanine amino transferase (ALT) and aspartate amino transferase (AST).

   • According to Gull N (2023)

     Excerpt Curcumin, the active ingredient in the Curcuma longa plant, has gained widespread attention in recent years because of its multifunctional properties as an antioxidant, anti-inflammatory, antimicrobial, & anticancer agent. Methods: A systematic search of PubMed, Embase & Google Scholar was performed for studies reporting incidence of HCC, risk factors associated with cirrhosis & experimental use of curcumin as an anti-cancer agent.

   • According to Yenny (2020)

     Excerpt Doxorubicin greatly increases the activity of SGOT & SGPT, & causes damage to liver tissue, but by giving a combination of the VCO & C Longa produces significant hepatoprotective effects. This study aimed to compare the hepatoprotective activity of Curcuma longa & Virgin Coconut Oil (VCO), by observing the activity of SGOT & SGPT.

Further indications (including other extraction modes where applicable), dosages, precautions for use, and the <strong>full scientific references</strong> (complete records, not only the short excerpts above) are available in the complete monographic record in the Lapo v2 application.