Cymbopogon citratus (Sitwonnèl) : medicinal properties in alcoholic extraction

Cymbopogon citratus (Sitwonnèl, Lemongrass, Citronnelle) — family Poacées.

Scientific synonyms : Andropogon citratus-DC, A.nardus-(L)-Duss, Cymbopogon nardus-(L)-Rendle.

Recognised external sources linked to this monograph: TRAMIL and French Pharmacopoeia.

This database documents alcoholic (ethanol) extractions of active substances. Our monograph currently lists 22 indications in alcoholic extraction for this species. The Lapo v2 catalogue records 76 scientific references for this species (full detail in the application).

Important — scientific references on this public page: only a short excerpt of each cited source is shown (selected abstract sentences), kept in the original language of the publication (most often English), without translation. These excerpts are not the full article text and are not a complete bibliography. The full reference records and complete monographic detail are available in the Lapo v2 application (free 30-day trial).

1. 1

   Type II diabetes mellitus

   Plant part used: leaf.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to Adegbegi JA (2015)

     Excerpt Findings in this study showed that this plant has Hypoglycemic properties & did not exert oxidative damage to the heart & the various hormonal profiles as well as its relative safety & possible use for weight gain. The present study was undertaken to investigate the effect of extracts of C citratus on the blood sugar level, lipid profiles & hormonal profiles of normal rats.

2. 2

   Liver fibrosis

   Plant part used: leaf.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to Naglaa AS Sarg (2015)

     Excerpt Aim of the work: This work is aimed to study the protective effect of C citratus ethanolic leaf extract against hepatic injury and fibrosis induced by repeated intermittent administration of Dimethyl nitrosamine (DMN) in rats. In conclusion: The results of this present study indicated that aqueous leaf extracts of C citratus has an Antihepatotoxic action against DMN induced hepatic oxidative damage in rats which might be ascribed to its antioxidant and free radical scavenging property.

   • According to Puatanachokchai R (2002)

     Excerpt Effects of lemon grass extract (LGE) on hepatocarcinogenesis were examined in male Fischer 344 rats, administered diethylnitrosamine (DEN) at three weekly intraperitoneal doses of 100 mg/kg body weight & partially hepatectomized at the end of week 5. These results suggest inhibitory effects of LGE on the early phase hepatocarcinogenesis in rats after initiation with DEN,.

   • According to Ekpenyong CE (2014)

     Excerpt citratus should be used with caution by individuals with kidney & liver diseases, pregnant or lactating women, patients on antiplatelet medication or clotting disorders, & in combination with drugs that depend on the cytochrome P450 enzyme system for their metabolism. citratus is relatively safe for consumption at any dose, recent evidence suggests that factors such as the variation in bioactive constituents & dose/duration of administration could influence its toxicological profile.

   • According to Koh PH (2012)

     Excerpt Koh PH et al: Antioxidant potential of Cymbopogon citratus extract: alleviation of carbon tetrachloride-induced hepatic oxidative stress and toxicity.

   • According to Pei HK (2012)

     Excerpt Pei HK et al, Antioxidant potential of Cymbopogon citratus extract: alleviation of carbon tetrachloride-induced hepatic oxidative stress & toxicity.

3. 3

   Cancer: chemoprevention of hepatocellular carcinoma

   Plant part used: leaf.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to Puatanachokchai R (2002)

     Excerpt Effects of lemon grass extract (LGE) on hepatocarcinogenesis were examined in male Fischer 344 rats, administered diethylnitrosamine (DEN) at three weekly intraperitoneal doses of 100 mg/kg body weight & partially hepatectomized at the end of week 5. These results suggest inhibitory effects of LGE on the early phase hepatocarcinogenesis in rats after initiation with DEN,.

   • According to Naglaa AS Sarg (2015)

     Excerpt Aim of the work: This work is aimed to study the protective effect of C citratus ethanolic leaf extract against hepatic injury and fibrosis induced by repeated intermittent administration of Dimethyl nitrosamine (DMN) in rats. In conclusion: The results of this present study indicated that aqueous leaf extracts of C citratus has an Antihepatotoxic action against DMN induced hepatic oxidative damage in rats which might be ascribed to its antioxidant and free radical scavenging property.

   • According to Ekpenyong CE (2014)

     Excerpt citratus should be used with caution by individuals with kidney & liver diseases, pregnant or lactating women, patients on antiplatelet medication or clotting disorders, & in combination with drugs that depend on the cytochrome P450 enzyme system for their metabolism. citratus is relatively safe for consumption at any dose, recent evidence suggests that factors such as the variation in bioactive constituents & dose/duration of administration could influence its toxicological profile.

   • According to Koh PH (2012)

     Excerpt Koh PH et al: Antioxidant potential of Cymbopogon citratus extract: alleviation of carbon tetrachloride-induced hepatic oxidative stress and toxicity.

   • According to Pei HK (2012)

     Excerpt Pei HK et al, Antioxidant potential of Cymbopogon citratus extract: alleviation of carbon tetrachloride-induced hepatic oxidative stress & toxicity.

Further indications (including other extraction modes where applicable), dosages, precautions for use, and the <strong>full scientific references</strong> (complete records, not only the short excerpts above) are available in the complete monographic record in the Lapo v2 application.