Cynodon dactylon (Ti-chiendan) : medicinal properties in alcoholic extraction

Cynodon dactylon (Ti-chiendan, Small couch grass, Petit Chiendent) — family Poacées.

Scientific synonyms : Panicum dactylon-(L)-Pers, capriola dactylon-Ktze.

Recognised external sources linked to this monograph: French Pharmacopoeia.

This database documents alcoholic (ethanol) extractions of active substances. Our monograph currently lists 17 indications in alcoholic extraction for this species. The Lapo v2 catalogue records 98 scientific references for this species (full detail in the application).

Important — scientific references on this public page: only a short excerpt of each cited source is shown (selected abstract sentences), kept in the original language of the publication (most often English), without translation. These excerpts are not the full article text and are not a complete bibliography. The full reference records and complete monographic detail are available in the Lapo v2 application (free 30-day trial).

1. 1

   Type II diabetes mellitus

   Plant part used: Aerial parts.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to Hajizadeh MR (2009)

     Excerpt Several effects including: antimicrobial, anti-diabetic & cardioprotective effects have been reported for Cynodon dactylon. Experimental groups (3 & 4) were treated with 1% ethylene glycol as well as 5mg/kg N-butanol fraction or 5mg/kg N-butanol phase remnant from 50% aqueous-ethanolic extract of C dactylon from first day of the experiment & continued during all protocol time.

   • According to Avvarai SK (2011)

     Excerpt The present study was undertaken to evaluate the antidiabetic activity of ethanolic extract of Cynodon dactylon root stalks in Streptozotocin induced Diabetic Rats as this type of scientific documentation was not filled so far. The anti-diabetic activity of ethanolic extract of C dactylon root stalks was evaluated in streptozotocin induced diabetic rats using Tolbutamide as standard.

   • According to RAHMAN S (2015)

     Excerpt Methods: To assess the antidiabetic activity of EECA, oral glucose tolerance test (OGTT) model and alloxan induced diabetic test (AIDT) model were performed. To explore the antidiabetic and the antidiarrhoeal effects of ethanolic extracts of Cynodon dactylon Pers.

   • According to Nishmitha S (2016)

     Excerpt Based on data collected from various research works on diabetes mellitus and the anti-diabetic potential of Cynodon dactylon, the current study was performed to investigate the anticataract potential of C. Photographic evaluation of lens opacity was done to compare & check the effectiveness & potential of C dactylon.

   • According to Singh SK (2007)

     Excerpt Singh SK et al, Assessment of antidiabetic potential of Cynodon dactylon extract in streptozotocin diabetic rats.

2. 2

   Microbial infection: Bacillus cereus, Bacillus subtilis, Escherichia coli, Klebsiella spp., Pseudomonas aeruginosa, Staphylococcus aureus, Streptococcus pyogenes, Streptococcus pneumoniae

   Plant part used: Sheet.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to Abdullah S (2012)

     Excerpt In this study, the antimicrobial activity of the plant crude extract from seven different solvents (acetone, chloroform, diethyl ether, ethanol, ethyl acetate, methanol, and n-pentane) was investigated against some pathogens (Bacillus Cereus, B subtilis, Escherichia coli, Klebsiella spp, Pseudomonas aeruginosa, Staphylococcus aureus, Streptococcus pyogenes, & S pneumonia) using disc diffusion method & thin-layer chromatographic (TLC) bioassay for plant-SPE extracts against A niger. The antimicrobial study revealed broad spectrum of antimicrobial activity from ethanol (7.0–10.0 ± 0.0–1.0 mm) & ethyl acetate (7.0–12.0 ± 0.0–1.0 mm) extracts against all of the bacterial pathogens.

   • According to PANDEY K (2016)

     Excerpt These used to investigate the phytochemical constituents of the plant were used to extract the bioactive compounds from the leaf of Cynodon dactylon to screen the antibacterial activity against infectious disease-causing bacterial pathogens (Escherichia coli also known as E. Cynodon dactylon (Leaf) is a type of Grass that possesses great medicinal values.

   • According to Hajizadeh MR (2009)

     Excerpt Several effects including: antimicrobial, anti-diabetic & cardioprotective effects have been reported for Cynodon dactylon. Experimental groups (3 & 4) were treated with 1% ethylene glycol as well as 5mg/kg N-butanol fraction or 5mg/kg N-butanol phase remnant from 50% aqueous-ethanolic extract of C dactylon from first day of the experiment & continued during all protocol time.

   • According to Suresh K (2008)

     Excerpt Suresh K et al, Antimicrobial & Phytochemical Investigation of the Leaves of Carica papaya L., Cynodon dactylon (L.) Pers., Euphorbia hirta L., Melia azedarach L.

   • According to Zabin K (2014)

     Excerpt Zabin K et al, Phytoconstituents investigation by LC-MS & evaluation of antimicrobial & anti-pyretic properties of Cynodon dactylon.

3. 3

   Hepatitis, cirrhosis, fatty liver, poisoning

   Plant part used: Sheet.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to Ramamurthy V (2015)

     Excerpt In conclusion, Cynodon dactylon was found to be safe and successful agent counteracting the Aflatoxins toxicity and protected against the toxicity induced by aflatoxin. dactylon acts as an effective compound playing an important role in reduction of hepatotoxicity & antioxidative property.

   • According to Singh SK (n.d.)

     Excerpt Singh SK et al, Protective effect of Cynodon dactylon against STZ induced hepatic injury in rats.

   • According to Singh SK (2009)

     Excerpt Singh SK et al, Curative effect of Cynodon dactylon against STZ induced hepatic injury in diabetic rats.

   • According to Saradha DKM (n.d.)

     Excerpt Saradha DKM et al, Hepatic antioxidative potential of ethyl acetate fraction of Cynodon dactylon in Balb/c mice.

   • According to Mozafari AA (2018)

     Excerpt Fatty acids (palmitic acid & linoleic acid) along with their methyl esters (ethyl palmitate, ethyl linoleate & ethyl oleate) & other derivatives (duomo-γ-linoleic acid) were the main identified constituents shortly after drying procedures; however, other components such as 5-hydroxymethylfurfural, maltol, retinol & phytol were also traced. Based on the 2,2-diphenyl-1-picrylhydrazyl (DPPH) free radical scavenging assay, the IC50 values were generally higher (significance level of 0.05) for oven-dried rhizome compared with shade-dried leaves & rhizomes that quenched more than 84% of the DPPH at the concentration of 400 mg/ml (IC50 59.12).

Further indications (including other extraction modes where applicable), dosages, precautions for use, and the <strong>full scientific references</strong> (complete records, not only the short excerpts above) are available in the complete monographic record in the Lapo v2 application.