Desmodium adscendens (Savannah clover) : medicinal properties in alcoholic extraction

Desmodium adscendens (Savannah clover, Brown pistachio, Trèf-savann, Pistach mawon, Trèfle-à-savane, Pistache marronne) — family Fabacées.

Scientific synonyms : Desmodium ovalifolium-Guill & Pert., Hedysarum adscencens-Sw, Meibolia adscendens-(Sw)-Kuntze..

Recognised external sources linked to this monograph: French Pharmacopoeia.

This database documents alcoholic (ethanol) extractions of active substances. Our monograph currently lists 7 indications in alcoholic extraction for this species. The Lapo v2 catalogue records 28 scientific references for this species (full detail in the application).

Important — scientific references on this public page: only a short excerpt of each cited source is shown (selected abstract sentences), kept in the original language of the publication (most often English), without translation. These excerpts are not the full article text and are not a complete bibliography. The full reference records and complete monographic detail are available in the Lapo v2 application (free 30-day trial).

1. 1

   Cancer: adjuvant treatment for hepatocellular carcinoma

   Plant part used: Aerial parts.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to Magielse J (2013)

     Excerpt The isolation of D-pinitol (or 3-O-methyl-D-chiro-inositol) from an aqueous decoction of Desmodium adscendens (Fabaceae) leaves & twigs is reported. Conclusions: The aqueous decoction of D.A showed a protective effect in rats against liver damage induced by D-galactosamine & ethanol, & this effect is at least in part due to the presence of D-pinitol.

   • According to Liu C (2013)

     Excerpt Modem pharmacological studies have showed that the Desmodium species have antioxidant, antibacterial, anti-inflammatory, hepatoprotective, diuretic, antipyretic, analgesic & choleretic activity. This article mainly has reviewed the research advances of chemical constituents & biological activities of Desmodium species since 2003.

   • According to Imperatori L (2018)

     Excerpt Desmodium adscendens is a plant that possesses anti-allergic, antioxidant & hepatoprotective properties. Conclusion: We found that chemotherapy, combined with Desmodium & Lithothamnium, improved pain & fatigue in head & neck cancer patients, although we cannot confirm if this was due to Desmodium & Lithothamnium or chemotherapy.

   • According to François C (2015)

     Excerpt adscendens (DA) on liver (HEPG2) & kidney (LLC-PK1) cells.

   • According to Van Doreen I (2014)

     Excerpt A decoction of the leaves & stems of Desmodium adscendens (Fabaceae), a herb occurring in Africa & South America, is used in traditional medicine. Our investigations have led to the identification of D-pinitol, a carbohydrate with antihyperglycemic, hepatoprotective & anti-inflammatory effects, as a potentially active compound.

2. 2

   Inflammatory back pain, myalgia

   Plant part used: Sheet.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to Liu C (2013)

     Excerpt Modem pharmacological studies have showed that the Desmodium species have antioxidant, antibacterial, anti-inflammatory, hepatoprotective, diuretic, antipyretic, analgesic & choleretic activity. This article mainly has reviewed the research advances of chemical constituents & biological activities of Desmodium species since 2003.

   • According to Zielinska-Pisklak MA (2014)

     Excerpt This study provides novel information concerning identity of the major compounds present in the leaves of DA cultivated in Ghana, which broadens the knowledge about anti-inflammatory, antiallergic & antioxidant properties of their extracts. The antioxidant activity of the crude extract (60% ethanol) from the leaves of Desmodium adscendens (Sw.) DC.

   • According to Imperatori L (2018)

     Excerpt Desmodium adscendens is a plant that possesses anti-allergic, antioxidant & hepatoprotective properties. Conclusion: We found that chemotherapy, combined with Desmodium & Lithothamnium, improved pain & fatigue in head & neck cancer patients, although we cannot confirm if this was due to Desmodium & Lithothamnium or chemotherapy.

   • According to N’GOUEMO (1996)

     Excerpt This study investigates some Pharmacological effects of the ethanolic extract of the leaves of Desmodium adscendens (Papilionaceae), a medicinal plant in the African traditional medicine, on the central nervous system. The plant extract induced hypothermia & had analgesic effect in mice.

   • According to Rastogi S (2011)

     Excerpt Crude extracts, fractions & isolated components of DG & DA showed a wide spectrum of in vitro & in vivo pharmacological activities like antileishmanial, immunomodulatory, antiasthmatic, smooth muscle relaxant, anti-inflammatory, antiulcer, cardioprotective, antidiabetic, antiamnesic, antiviral, antioxidant & hepatoprotective activities. & Desmodium adscendens (Sw.) DC are two important & well explored species of genus Desmodium (Fabaceae (alt.

3. 3

   Asthma

   Plant part used: Sheet.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to Rastogi S (2011)

     Excerpt Crude extracts, fractions & isolated components of DG & DA showed a wide spectrum of in vitro & in vivo pharmacological activities like antileishmanial, immunomodulatory, antiasthmatic, smooth muscle relaxant, anti-inflammatory, antiulcer, cardioprotective, antidiabetic, antiamnesic, antiviral, antioxidant & hepatoprotective activities. DG is used as a tonic, febrifuge, digestive, anticatarrhal, antiemetic, in inflammatory conditions of chest & in various other inflammatory conditions in the Ayurvedic System of Medicine while DA is widely used for the treatment of asthma in Ghana, Africa.

   • According to Manzione MG (2022)

     Excerpt Desmodium adscendens (Sw.) DC. This herb has been traditionally used in numerous countries all over the world for its pharmacological and biological properties (i.e., it has been used for the treatment of diarrheas, fever, epilepsy, asthma, leishmaniasis, gastroduodenal ulcer, diabetes, hepatic diseases, etc.).

   • According to Zielinska-Pisklak MA (2014)

     Excerpt The antioxidant activity of the crude extract (60% ethanol) from the leaves of Desmodium adscendens (Sw.) DC. This study provides novel information concerning identity of the major compounds present in the leaves of DA cultivated in Ghana, which broadens the knowledge about anti-inflammatory, antiallergic & antioxidant properties of their extracts.

   • According to Liu C (2013)

     Excerpt Modem pharmacological studies have showed that the Desmodium species have antioxidant, antibacterial, anti-inflammatory, hepatoprotective, diuretic, antipyretic, analgesic & choleretic activity. This article mainly has reviewed the research advances of chemical constituents & biological activities of Desmodium species since 2003.

   • According to Addy ME (1988)

     Excerpt Addy ME et al, Effect of Desmodium adscendens fractions on antigen- & arachidonic acid-induced contractions of guinea pig airways.

Further indications (including other extraction modes where applicable), dosages, precautions for use, and the <strong>full scientific references</strong> (complete records, not only the short excerpts above) are available in the complete monographic record in the Lapo v2 application.