Duranta repens (Vaniy-mawon) : medicinal properties in alcoholic extraction

Duranta repens (Vaniy-mawon, Brown vanilla, Vanille marrone) — family Verbénacées.

Scientific synonyms : Duranta angustifolia Salisb., D erecta-Jacq, D plumieri-Jacq, Ellisia acuta L..

This database documents alcoholic (ethanol) extractions of active substances. Our monograph currently lists 7 indications in alcoholic extraction for this species. The Lapo v2 catalogue records 71 scientific references for this species (full detail in the application).

Important — scientific references on this public page: only a short excerpt of each cited source is shown (selected abstract sentences), kept in the original language of the publication (most often English), without translation. These excerpts are not the full article text and are not a complete bibliography. The full reference records and complete monographic detail are available in the Lapo v2 application (free 30-day trial).

1. 1

   Liver disorders, liver stress, abnormal serum parameters: ALT, ASP, ALP, γGT, Bil, MDA, bilirubin, etc.

   Plant part used: Fruit.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to DONKAR S (2025)

     Excerpt The effect of treatment on haematological parameters, biochemical markers such as aspartate aminotransferase (AST), alanine aminotransferase (ALT), alkaline phosphatase (ALP), total bilirubin (TBil), alpha-fetoprotein (AFP), liver oxidative stress markers & inflammatory cytokines (interleukin [IL]-17, IL-23, nuclear factor kappa beta [NF-kB], & cycloxygenase-2 [COX-2]) as well as liver histology were evaluated. This work evaluated the hepatoprotective effect of Duranta erecta leaves (DRL) & ripe fruit (DRR) extracts on subacute CCl4-induced hepatotoxicity in experimental animal models.

   • According to DONKOR S (2020)

     Excerpt This study aimed at determining the acute hepatoprotective efficacy of Duranta erecta hydroethanolic extracts of leaves, ripe & unripe fruits against CCl4-, & acetaminophen-induced hepatotoxicity in animals. Hepatoprotective efficacy was assessed by assaying serum biochemical markers such as alanine aminotransferase (ALT), aspartate aminotransferase (AST), alkaline phosphatase (ALP), gamma-glutamyl transferase (γGT), bilirubin (Bil), antioxidative biomarkers including reduced glutathione (GSH), glutathione peroxidase (GPx), glutathione transferase (GST), superoxide dismutase (SOD), malondialdehyde (MDA), hydrogen peroxidase (H202),&d nitric oxide (NO), as well as histological observations.

   • According to Khanal P (2022)

     Excerpt The present study investigated the effect of hydroalcoholic extract of Duranta repens over gluconeogenesis, glycolysis, glycogenesis, leptin, & dipeptidyl peptidase-4 regulation in fructose-induced insulin-resistant rats. Additionally, molecular docking revealed scutellarein, pseudo-ginsenoside-RT1, repennoside, & durantanin I as the probable lead hits in regulating the enzymes involved in hepatic glucose catabolism & anabolism.

   • According to Donkor s (2020)

     Excerpt The subacute toxicity assessment resulted in overall body weight increase, a change in relative organ weight of the liver, lung, stomach, & changes in the haematological indices such as HCT%, LYM%, RDW-SD/fL, MCHC, MCV/fL, P-LCR% & biochemical parameters namely ALT, AST, LDH & creatinine of the tested group relative to the normal. The positive activity of the extract on liver enzymes & LDH is an indication of its good hepatoprotective potential.

   • According to Vivar JLA (2016)

     Excerpt Chemical investigation of the dichloromethane extract of the flowers of Duranta erecta L.

2. 2

   Bacterial infection: Bacillus subtilis, Pseudomonas aeruginosa, Staphylococcus aureus and Escherichia coli

   Plant part used: Fruit.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to Prabhakar GP (2015)

     Excerpt Bacillus subtilis, Pseudomonas aeruginosa, Staphylococcus aureus & Escherichia coli. Water & methanolic extracts of CV showed maximum inhibition effects against Bacillus subtilis & Pseudomonas aeruginosa., l,.

   • According to BUTTLE SR (2024)

     Excerpt Plant parts such as leaves, fruit, stem, & flowers have been reported for possessing antimalarial, antibacterial, antioxidant, & cytotoxic activity. is a small to moderate size plant of family Verbenaceae, commonly called as Skyflower, Pigeon berry, Golden dewdrop, Creeping Skin Flower.

   • According to Sharma P (2012)

     Excerpt As a result of antifungal activity it was found that the extract of leaf generally revealed antifungal activity against all Aspergillus spp. The present study describes the antifungal activity of Durenta erecta L.

   • According to Abou-Setta M (2007)

     Excerpt The ethylacetate fraction of the methanol extract of Duranta repens showed radical scavenging activity in the 1, 1‐diphenyl‐2‐picrylhydrazyl (DPPH) assay.

   • According to Al-deen S (2009)

     Excerpt A study were conducted to examinate the effect of organic & aqueous (Hot, Cold) Extracts from leaves of Duranta repens on the growth & activities of the following types of Bacteria:- Staphylococcus aureus, Streptococcus pyogens ,Escherichia coli, Klebsilla pneumonia, in addition to the yeast Candida albicans the fungi Aspergullis niger, Aspergulls flavus.

3. 3

   Cancer: adjuvant treatment for lung and ovarian carcinoma

   Plant part used: Whole plant.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to Khanal P (2020)

     Excerpt To report in vitro anti-oxidant activity & cytotoxicity of hydroalcoholic extract of Ficus benghalensis (bark) & Duranta repens (whole plant), & present the probable biological spectrum of major anti-oxidants from both plants. Cytotoxicity of both extracts was evaluated using MTT assay in both tumor & normal cell lines i.e.

   • According to KHANAL P (2021)

     Excerpt Duranta repens is reported to contain a wide array of secondary metabolites, including α-amylase & α-glucosidase inhibitors, and - has potent antioxidant activity. repens (whole plant) with targets related to diabetes mellitus & assessed its outcome by evaluating the effects of the hydroalcoholic extract of D.

   • According to Thomas PS (2019)

     Excerpt The plant has been shown to have some therapeutic activities, such as antithrombin, antioxidant, anticancer, antiviral, larvicidal, & antiplasmodial activities [1, 3-7]. repens is an evergreen shrub native to tropical America, & it is distributed in most tropical & subtropical regions [1].

   • According to Srivastava M (1963)

     Excerpt Results : DE & its key metabolite acteoside display various biological actions like antimalarial, antimicrobial, antioxidant, anticancer, antinephritic, hepatoprotective, neuroprotective, & antiviral properties.

   • According to Donkor s (2020)

     Excerpt The subacute toxicity assessment resulted in overall body weight increase, a change in relative organ weight of the liver, lung, stomach, & changes in the haematological indices such as HCT%, LYM%, RDW-SD/fL, MCHC, MCV/fL, P-LCR% & biochemical parameters namely ALT, AST, LDH & creatinine of the tested group relative to the normal. Duranta erecta is used in folklore medicine for the treatment of myriad of diseases in Africa.

Further indications (including other extraction modes where applicable), dosages, precautions for use, and the <strong>full scientific references</strong> (complete records, not only the short excerpts above) are available in the complete monographic record in the Lapo v2 application.