Duranta repens (Vaniy-mawon) : vertus médicinales en extraction alcoolique

Duranta repens (Vaniy-mawon, Vanille marrone, Brown vanilla) — famille Verbénacées.

Synonymes scientifiques : Duranta angustifolia Salisb., D erecta-Jacq, D plumieri-Jacq, Ellisia acuta L..

Cette base documente les extractions alcooliques (éthanol) des substances actives. Notre monographie recense actuellement 7 indications en extraction alcoolique pour cette espèce. Le catalogue Lapo v2 enregistre 71 références scientifiques pour cette espèce (détail intégral dans l’application).

Important — références scientifiques sur cette page publique : seuls de courts extraits de chaque source citée sont présentés (phrases d’abstract sélectionnées), conservés dans leur langue d’origine (le plus souvent l’anglais), sans traduction. Ces extraits ne constituent pas le texte intégral de l’article ni une bibliographie complète. Les fiches de référence complètes et le détail monographique sont disponibles dans l’application Lapo v2 (essai gratuit 30 jours).

1. 1

   Troubles hépatiques, stress hépatique, anormalité des paramètres sériques : ALT, ASP, ALP, γGT, Bil, MDA, Bilirubine, etc

   Partie usitée : Fruit. Profil pharmacologique documenté : Silymarine-like.

   Références scientifiques (courts extraits)

   Courts extraits uniquement (pas le texte intégral de l’article). Fiches de référence complètes dans l’application Lapo v2.

   • Selon DONKAR S (2025)

     Extrait The effect of treatment on haematological parameters, biochemical markers such as aspartate aminotransferase (AST), alanine aminotransferase (ALT), alkaline phosphatase (ALP), total bilirubin (TBil), alpha-fetoprotein (AFP), liver oxidative stress markers & inflammatory cytokines (interleukin [IL]-17, IL-23, nuclear factor kappa beta [NF-kB], & cycloxygenase-2 [COX-2]) as well as liver histology were evaluated. This work evaluated the hepatoprotective effect of Duranta erecta leaves (DRL) & ripe fruit (DRR) extracts on subacute CCl4-induced hepatotoxicity in experimental animal models.

   • Selon DONKOR S (2020)

     Extrait This study aimed at determining the acute hepatoprotective efficacy of Duranta erecta hydroethanolic extracts of leaves, ripe & unripe fruits against CCl4-, & acetaminophen-induced hepatotoxicity in animals. Hepatoprotective efficacy was assessed by assaying serum biochemical markers such as alanine aminotransferase (ALT), aspartate aminotransferase (AST), alkaline phosphatase (ALP), gamma-glutamyl transferase (γGT), bilirubin (Bil), antioxidative biomarkers including reduced glutathione (GSH), glutathione peroxidase (GPx), glutathione transferase (GST), superoxide dismutase (SOD), malondialdehyde (MDA), hydrogen peroxidase (H202),&d nitric oxide (NO), as well as histological observations.

   • Selon Khanal P (2022)

     Extrait The present study investigated the effect of hydroalcoholic extract of Duranta repens over gluconeogenesis, glycolysis, glycogenesis, leptin, & dipeptidyl peptidase-4 regulation in fructose-induced insulin-resistant rats. Additionally, molecular docking revealed scutellarein, pseudo-ginsenoside-RT1, repennoside, & durantanin I as the probable lead hits in regulating the enzymes involved in hepatic glucose catabolism & anabolism.

   • Selon Donkor s (2020)

     Extrait The subacute toxicity assessment resulted in overall body weight increase, a change in relative organ weight of the liver, lung, stomach, & changes in the haematological indices such as HCT%, LYM%, RDW-SD/fL, MCHC, MCV/fL, P-LCR% & biochemical parameters namely ALT, AST, LDH & creatinine of the tested group relative to the normal. The positive activity of the extract on liver enzymes & LDH is an indication of its good hepatoprotective potential.

   • Selon Vivar JLA (2016)

     Extrait Chemical investigation of the dichloromethane extract of the flowers of Duranta erecta L.

2. 2

   Infection bactérienne : Bacillus subtilis, Pseudomonas aeruginosa, Staphylococcus aureus & Escherichia coli

   Partie usitée : Fruit.

   Références scientifiques (courts extraits)

   Courts extraits uniquement (pas le texte intégral de l’article). Fiches de référence complètes dans l’application Lapo v2.

   • Selon Prabhakar GP (2015)

     Extrait Bacillus subtilis, Pseudomonas aeruginosa, Staphylococcus aureus & Escherichia coli. Water & methanolic extracts of CV showed maximum inhibition effects against Bacillus subtilis & Pseudomonas aeruginosa., l,.

   • Selon BUTTLE SR (2024)

     Extrait Plant parts such as leaves, fruit, stem, & flowers have been reported for possessing antimalarial, antibacterial, antioxidant, & cytotoxic activity. is a small to moderate size plant of family Verbenaceae, commonly called as Skyflower, Pigeon berry, Golden dewdrop, Creeping Skin Flower.

   • Selon Sharma P (2012)

     Extrait As a result of antifungal activity it was found that the extract of leaf generally revealed antifungal activity against all Aspergillus spp. The present study describes the antifungal activity of Durenta erecta L.

   • Selon Abou-Setta M (2007)

     Extrait The ethylacetate fraction of the methanol extract of Duranta repens showed radical scavenging activity in the 1, 1‐diphenyl‐2‐picrylhydrazyl (DPPH) assay.

   • Selon Al-deen S (2009)

     Extrait A study were conducted to examinate the effect of organic & aqueous (Hot, Cold) Extracts from leaves of Duranta repens on the growth & activities of the following types of Bacteria:- Staphylococcus aureus, Streptococcus pyogens ,Escherichia coli, Klebsilla pneumonia, in addition to the yeast Candida albicans the fungi Aspergullis niger, Aspergulls flavus.

3. 3

   Cancer : traitement adjuvant du carcinome pulmonaire & ovarien

   Partie usitée : Plante entière.

   Références scientifiques (courts extraits)

   Courts extraits uniquement (pas le texte intégral de l’article). Fiches de référence complètes dans l’application Lapo v2.

   • Selon Khanal P (2020)

     Extrait To report in vitro anti-oxidant activity & cytotoxicity of hydroalcoholic extract of Ficus benghalensis (bark) & Duranta repens (whole plant), & present the probable biological spectrum of major anti-oxidants from both plants. Cytotoxicity of both extracts was evaluated using MTT assay in both tumor & normal cell lines i.e.

   • Selon KHANAL P (2021)

     Extrait Duranta repens is reported to contain a wide array of secondary metabolites, including α-amylase & α-glucosidase inhibitors, and - has potent antioxidant activity. repens (whole plant) with targets related to diabetes mellitus & assessed its outcome by evaluating the effects of the hydroalcoholic extract of D.

   • Selon Thomas PS (2019)

     Extrait The plant has been shown to have some therapeutic activities, such as antithrombin, antioxidant, anticancer, antiviral, larvicidal, & antiplasmodial activities [1, 3-7]. repens is an evergreen shrub native to tropical America, & it is distributed in most tropical & subtropical regions [1].

   • Selon Srivastava M (1963)

     Extrait Results : DE & its key metabolite acteoside display various biological actions like antimalarial, antimicrobial, antioxidant, anticancer, antinephritic, hepatoprotective, neuroprotective, & antiviral properties.

   • Selon Donkor s (2020)

     Extrait The subacute toxicity assessment resulted in overall body weight increase, a change in relative organ weight of the liver, lung, stomach, & changes in the haematological indices such as HCT%, LYM%, RDW-SD/fL, MCHC, MCV/fL, P-LCR% & biochemical parameters namely ALT, AST, LDH & creatinine of the tested group relative to the normal. Duranta erecta is used in folklore medicine for the treatment of myriad of diseases in Africa.

D’autres indications (y compris d’autres modes d’extraction le cas échéant), posologies, précautions d’emploi et les <strong>références scientifiques complètes</strong> (fiches intégrales, pas seulement les courts extraits ci-dessus) sont disponibles dans la fiche monographique de l’application Lapo v2.