Euterpe oleracea (Wasay) : medicinal properties in alcoholic extraction

Euterpe oleracea (Wasay, Açai) — family Arecacées.

Scientific synonyms : Euterpe badiocarpa Barb.Rodr, E beardii L.H.Bailey, E cuatrecasana Dugand, Catis mariana O.F.Cook..

This database documents alcoholic (ethanol) extractions of active substances. Our monograph currently lists 5 indications in alcoholic extraction for this species. The Lapo v2 catalogue records 94 scientific references for this species (full detail in the application).

Important — scientific references on this public page: only a short excerpt of each cited source is shown (selected abstract sentences), kept in the original language of the publication (most often English), without translation. These excerpts are not the full article text and are not a complete bibliography. The full reference records and complete monographic detail are available in the Lapo v2 application (free 30-day trial).

1. 1

   Cancer: adjuvant treatment for neuroblastoma

   Plant part used: Fruit.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to Aliaño-González MJ (2020)

     Excerpt Both of them are responsible of interesting properties of the fruit such as anti-inflammatory, antioxidant or anticancer.

   • According to Ferreira Silva D (2014)

     Excerpt This discovery of the anticancer potential of EO may help in the development of chemopreventive drugs & may have therapeutic effects in the treatment of breast cancer. Açaí is an abundant & much consumed fruit by the Amazon local population, & studies have demonstrated that it is rich in phytochemicals with antioxidant, anti-inflammatory, & anticancer activities.

   • According to Barros L (2015)

     Excerpt EO seeds extract revealed a high antioxidant (EC50 ranging from 3.6 to 19.4 μg/mL) & cytotoxic activity, being more effective in the cervical carcinoma cell line (HeLa; GI50 = 18 μg/mL); it did not show toxicity for non-tumor cells. The Euterpe oleracea Mart.

   • According to Heinrich M (2011)

     Excerpt Euterpe oleracea has been acclaimed to have a wide range of health-promoting & therapeutic benefits due to its reportedly high levels of antioxidants. This is based to a relatively high content of polyphenols, which in turn has been linked to a range of reported (mostly in vitro) antioxidant, anti-inflammatory, antiproliferative & cardioprotective properties.

   • According to Soares de Almeida Magalhães S (2020)

     Excerpt Euterpe oleracea Mart. EO leaves, fruits, & oil stand out for their large number of pharmacological activities such as anti-inflammatory, antioxidant, antimicrobial, antinociceptive, anticancer, anti-atherogenic, and healing activities, protection against metabolic syndromes such as diabetes, hypertension, & hyperlipidemia, and protection of organs such as lung, kidney, liver, heart, & nervous system.

2. 2

   Oxidative stress

   Plant part used: Seed.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to da Silva Santos V (2014)

     Excerpt In view of the high antioxidant & anti-inflammatory properties of the exotic Brazilian fruit Euterpe oleracea & its methanolic extract was obtained by solid-phase extraction (SPE). Specifically, the açaí extract at an optimal & nutritionally relevant concentration of 0.1 g/ml prevented Mn-induced oxidative stress by (1) restoring GSH GSSG ratio & net glutamate uptake, (2) protecting astrocytic membranes from lipid peroxidation, & (3) decreasing Mn-induced expression of erythroid 2-related fac-tor (Nrf2) protein.

   • According to Author (2015)

     Excerpt The seeds of Euterpe oleracea are rich in polyphenols with antihypertensive & antioxidant properties. The increased oxidative damage in the 2K1C group, assessed by lipid peroxidation & protein oxidation, was reduced by ASE, but Enalapril only reduced lipid peroxidation in mesenteric arterial bed (MAB) homogenate.

   • According to Cavalcante P (2018)

     Excerpt Euterpe oleracea is a fruit that stands out for presenting this property, & even though Brazil is the largest producer of this fruit, the foreign market has been investing in its exportation for use in both the food & pharmaceutical industries. Thus, it was observed that EO is a fruit rich in anthocyanins, which act by modulating the lipid metabolism to overcome the damage caused in the body by the oxidative stress unleashed by chronic diseases.

   • According to Martin Magalhães F (2021)

     Excerpt Our study aimed to investigate the effect of Açaí (Euterpe oleracea Martius) on the antioxidant response in BALB/c mice pretreated with Açaí pulp (200 g/kg) for 14 days. Our results demonstrated the protective effect of EO pulp components on intestinal damage induced by 5-FU, as well as the ability to control the response to oxidative stress, in order to mobilize defense pathways & promote tissue repair,.

   • According to Oliveira de Souza M (2010)

     Excerpt Oliveira de Souza M et al, Diet supplementation with acai (Euterpe oleracea Mart.) pulp improves biomarkers of oxidative stress & the serum lipid profile in rats.

3. 3

   Endometriosis

   Plant part used: Seed.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to Machado DE (2016)

     Excerpt This study investigated the therapeutic potential of Euterpe oleracea extract (açai) on the growth & survival of endometriotic lesions using an experimental model. Our results suggest that açai effectively suppressed the establishment & growth of endometriotic lesions, & this agent is a promising novel pharmacological therapeutic treatment for endometriosis.

Further indications (including other extraction modes where applicable), dosages, precautions for use, and the <strong>full scientific references</strong> (complete records, not only the short excerpts above) are available in the complete monographic record in the Lapo v2 application.