Helianthus annuus (Sunflower) : medicinal properties in alcoholic extraction

Helianthus annuus (Sunflower, Tournesol) — family Asteracées.

Scientific synonyms : Helianthus lenticularis-Douglas.

This database documents alcoholic (ethanol) extractions of active substances. Our monograph currently lists 19 indications in alcoholic extraction for this species. The Lapo v2 catalogue records 147 scientific references for this species (full detail in the application).

Important — scientific references on this public page: only a short excerpt of each cited source is shown (selected abstract sentences), kept in the original language of the publication (most often English), without translation. These excerpts are not the full article text and are not a complete bibliography. The full reference records and complete monographic detail are available in the Lapo v2 application (free 30-day trial).

1. 1

   Type II diabetes mellitus

   Plant part used: Seed.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to Saini S (2013)

     Excerpt Administration of extract in streptozotocin-nicotinamide induced diabetic rats, significantly decreased the blood glucose level (P<0.001) comparable to Glibenclamide (600 µg/kg), restored the lipid profile, showed improvement in body weight, liver glycogen content, glycosylated haemoglobin, plasma Malondialdehyde, glutathione level & serum insulin levels in diabetic rats. Materials & methods: The antihyperglycaemic effect of ethanol extract at 250mg/kg & 500mg/kg is studied in normal, glucose loaded hyperglycemic é streptozotocin (STZ) induced Type2 diabetic rats.

   • According to Onoja S.O (2018)

     Excerpt To investigate the hypoglycemic, antidyslipidemic, hepatoprotective & anti-lipid peroxidation effects of hydromethanol leaf extract of Helianthus annuus (HLEHA) in alloxan-induced diabetic rats. Glibenclamide (GLB) 2 mg/kg was used as a reference drug (positive control) and 5 % Tween-20 solution in water was used as negative control.

   • According to Luka C.D (2013)

     Excerpt : The aim of this study was to determine the hypoglycaemic effects & compare some biochemical parameters of aqueous extracts of four plants; Anacardium occidentale stem bark (CS), Moringa oleifera (ML), Vernonia amygdalina (BL) & Helianthus annuus seeds (SF) on alloxan induced diabetic rats. Significant reduction (p<0.05) was recorded in glucose level of the alloxan induced diabetic rats treated with CS, ML, BL & SF, expressing their hypoglycaemic potentials & competing favourably with the reference drug metformin.

   • According to Ojo AB (2017)

     Excerpt The present study evaluates the antihyperglycemic, antiperoxidative & antihyperlipidemic activities of saponins from Helianthus annuus roots in alloxan induced diabetic rats. Results: suggest that saponins from HA root can enhance the antihyperglycemic, antihyperlipidemic & antioxidant properties in alloxan-induced diabetic rats, & may have the potential to be used in the prevention or in the management of diabetes.

   • According to Onoja, S.O (2014)

     Excerpt Onoja, S.O et al, Evaluation of the antidiabetic & antioxidant potentials of methanolic leaf extract of Helianthus annuus L on alloxan-induced hyperglycemic rats.

2. 2

   Inflammatory condition: adjuvant treatment for rheumatoid arthritis

   Plant part used: Sheet.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to Author (2015)

     Excerpt Methods: The effect of HA was evaluated for chronic inflammation by complete Freund’s adjuvant (CFA) induced arthritis in rats. The present study was carried out to investigate the antiarthritic potential of ethanolic extract of Helianthus annuus leaves (HA).

   • According to Author (2011)

     Excerpt It has antioxidant, anticancer, anti-inflammatory, antihypertensive, skin-protective, hypocholesterolemic, analgesic, & antibacterial activities & calming effects on the nerves, muscles, & blood vessels. Helianthus annuus seed preparations have found widespread use in traditional medicine.

   • According to Onoja SO (2019)

     Excerpt Onoja SO et al, Anti-inflammatory & analgesic activities of methanol extract of Helianthus annuus Linn (Asteraceae) leaf.

   • According to Ukaya M (2007)

     Excerpt Ukaya M et al, Triterpene glycosides from the flower petals of Sun Flower (Helianthus annuus) & their anti-inflammatory activity.

   • According to Ejebe ED (2010)

     Excerpt To investigate the anti-inflammatory & analgesic effects of the ethanol extract of leaves of Helianthus annuus in acclimatized Wistar rats. Conclusions: These observations confirmed the presence of a strong anti-inflammatory & antinociceptive activity in the ethanol extract of the leaves of HA & therefore validated the folkloric use of the leaves of this plant in treatment of proinflammatory, post traumatic situations.

3. 3

   Diarrhoea

   Plant part used: Sheet.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to Dwivedi A (2015)

     Excerpt The objective of this study was to evaluate the anti-diarrheal & antihistaminic activity of ethanolic extract of 250 mg/kg & 500 mg/kg body weight using castor oil induced diarrhea & gastrointestinal transit model for anti-diarrheal activity & histaminic induced bronchoconstriction on guinea pig & microsbock model on rabbits for antihistaminic activity. Results also confirmed that HA decrease the severity of diarrhea & possesses the anti-histaminic potential to treat allergic disorders.

   • According to Boriollo MFG (2017)

     Excerpt The preventive action of diuresis, diarrhea & inflammatory diseases, besides the effects of relief of asthmatic symptoms, gastric protection, healing, anti-inflammatory & antimicrobial action were recognized regarding the pharmacological properties of HA. The present review gathers information about the genotoxic aspects of Helianthus annuus, until the present moment in the literature.

   • According to Ejebe DE (2008)

     Excerpt The time & dose dependent effects of ingestion of the ethanol extract of the leaves of Helianthus annuus, 0.5g/kg & 2g/kg body weight for 28days, on the histology of the testes, Epididymal sperm properties, blood levels of Testosterone, Follicle stimulating hormone & Luteinizing hormone of male Wistar rats were investigated in two phases. We conclude from this study that the ethanol extract of the leaves of HA possesses anti-spermatogenic /antifertility potentials that may be harnessed for contraception but further investigation in this regard is required.

   • According to Onoja S.O (2018)

     Excerpt To investigate the hypoglycemic, antidyslipidemic, hepatoprotective & anti-lipid peroxidation effects of hydromethanol leaf extract of Helianthus annuus (HLEHA) in alloxan-induced diabetic rats.

   • According to Ejebe ED (2010)

     Excerpt To investigate the anti-inflammatory & analgesic effects of the ethanol extract of leaves of Helianthus annuus in acclimatized Wistar rats. Conclusions: These observations confirmed the presence of a strong anti-inflammatory & antinociceptive activity in the ethanol extract of the leaves of HA & therefore validated the folkloric use of the leaves of this plant in treatment of proinflammatory, post traumatic situations.

Further indications (including other extraction modes where applicable), dosages, precautions for use, and the <strong>full scientific references</strong> (complete records, not only the short excerpts above) are available in the complete monographic record in the Lapo v2 application.