Hymenocallis littoralis (Lonyon-di-lis) : medicinal properties in alcoholic extraction

Hymenocallis littoralis (Lonyon-di-lis, Onion-de-Lys) — family Amaryllidacées.

Scientific synonyms : Hymenocallis adnat- Herb., H tennuiflor- Herb, Pancratium littorale Jacq., P illyricum-Blanco.

This database documents alcoholic (ethanol) extractions of active substances. Our monograph currently lists 5 indications in alcoholic extraction for this species. The Lapo v2 catalogue records 69 scientific references for this species (full detail in the application).

Important — scientific references on this public page: only a short excerpt of each cited source is shown (selected abstract sentences), kept in the original language of the publication (most often English), without translation. These excerpts are not the full article text and are not a complete bibliography. The full reference records and complete monographic detail are available in the Lapo v2 application (free 30-day trial).

1. 1

   Rheumatism, osteoarthritis, arthritis, oedema

   Plant part used: Flower.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to Karthikeyan R (2016)

     Excerpt The successive ethanol extract has shown potent anti-inflammatory activity by HRBC membrane stabilization method with 83.46% & 84.72% for 100 & 500 μg/ml, respectively. These results show that ethanol extract of HL has anti-inflammatory properties & can reduce inflammatory injury & tissue damage.

   • According to Jaiswal P (2022)

     Excerpt The aim of the present study was to carry out detail pharmacognostic analysis of hymenocallis littoralis, family: amaryllidaceae. The macroscopic study of leaf showed smooth leaf surface with entire margin while venation was parallel, acute at apex & flower was white in Color with six petals & 6 seamen with dorsifixed anther, while stigma was minute & trilocular & superior ovary.

   • According to Duan ZW (2021)

     Excerpt Perennial herb Hymenocallis littoralis(Amaryllidaceae) boasts anti-tumor, anti-virus, & anti-inflammatory activities. littoralis & their contribution to the various pharmacological activities of the herb.

   • According to Zhang J (2022)

     Excerpt Aim of the study : The aim of this paper is to investigate the anti-inflammatory potential & molecular mechanism of HL against lipopolysaccharide (LPS)-induced macrophages & in vivo HCl/EtOH-induced gastritis mucosal injury models. Conclusions: Cumulatively, these results demonstrated that HL exerts eminently anti-inflammatory activities in LPS-stimulated RAW264.7 cells in vitro & in HCl/EtOH-induced gastritis mice models in vivo.

   • According to Karthikeyan R (2016)

     Excerpt In our previous studies, a mixture of major three alkaloid components (5, 6-dihydro-bicolorine, 7-deoxy-trans-dihydronarciclasine, littoraline) from Hymenocallis littoralis were extracted, analyzed & designated as AHL. Alkaloids are the most extensively featured compounds of natural anti-tumor herbs, which have attracted much attention in pharmaceutical research.

2. 2

   Cancer: adjuvant treatment of gastric, liver and breast cancer

   Plant part used: Sheet.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to Karthikeyan R (2016)

     Excerpt In this paper, AHL extracts were added to human liver hepatocellular cells HepG-2, human gastric cancer cell SGC-7901, human breast adenocarcinoma cell MCF-7 & human umbilical vein endothelial cell EVC-304, to screen one or more AHL-sensitive tumor cell. In our previous studies, a mixture of major three alkaloid components (5, 6-dihydro-bicolorine, 7-deoxy-trans-dihydronarciclasine, littoraline) from Hymenocallis littoralis were extracted, analyzed & designated as AHL.

   • According to JI YB (2014)

     Excerpt In this paper, AHL extracts were added to human liver hepatocellular cells HepG-2, human gastric cancer cell SGC-7901, human breast adenocarcinoma cell MCF-7 & human umbilical vein endothelial cell EVC-304, to screen one or more AHL-sensitive tumor cell. In our previous studies, a mixture of major three alkaloid components (5, 6-dihydrobicolorine, 7-deoxy-trans-dihydro-narciclasine, littoraline) from Hymenocallis littoralis were extracted, analyzed & designated as AHL.

   • According to Sahgat G (2017)

     Excerpt Spider lily or scientifically known as Hymenocallis littoralis is an ornamental plant which widely used as folk medicine among Malaysians. This study was conducted to achieve the correlation between brine shrimp lethality test (BSL test) & the anticancer activity in various parts of the HL methanol extracts (HLM extract).

   • According to Idso SB (2000)

     Excerpt Two 2-yr crops of tropical spider lily (Hymenocallis littoralis) plants were grown in field soil in clear-plastic-wall open-top enclosures in the Sonoran Desert environment of central Arizona. It also increased the concentrations of five bulb constituents that have been demonstrated to possess anticancer and antiviral activities.

   • According to Ma W (2022)

     Excerpt Seven undescribed Amaryllidaceae alkaloids classified into four types, including the plicamine-type, secoplicamine-type, belladine-type & pretazettine-type, along with another three alkaloids that have not been isolated from plant material & seven known alkaloids, were isolated from the bulbs of Hymenocallis littoralis (Jacq.) Salisb. The isolated alkaloids were screened for antiproliferative activity against four human tumour cell lines (HepG2, HeLa, SPC-A-1, FaDu) through MTT assay, & some alkaloids exhibited potent cytotoxicity.

3. 3

   Bacterial infection: Escherichia coli, Staphylococcus aureus, Pseudomonas aeruginosa, Salmonella typhimurium

   Plant part used: Stem.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to SINGH G (2016)

     Excerpt The present study reports that the screening of antimicrobial activity of Tinospora cordifolia & Hymenocallis littoralis, medicinal plant’s extracts with various different plant parts such as bulb, root, leaves & stem against the opportunistic organisms such as Staphylococcus aureus, Escherichia coli, Pseudomonas aeruginosa, Salmonella Typhimurium & fungi Candida albicans using agar well diffusion method & Minimum inhibitory concentration (MIC). littoralis against Escherichia coli followed Staphylococcus aureus, Pseudomonas aeruginosa, Salmonella Typhimurium, Candida albicans produced highest zone of inhibition at 24mm followed by 21mm, 18 mm, 17mm & 17mm respectively.

   • According to Rosli (2014)

     Excerpt Study was carried out to determine the effect of HL leaf extract on the growth & morphogenesis of two pathogenic microbes, Candida albicans & Escherichia coli. Hymenocallis littoralis (Jacq.) Salisb (Melong kecil) commonly known as 'Spider Lily' is an herbaceous plant from the family Amaryllidaceae.

   • According to Idso SB (2000)

     Excerpt Two 2-yr crops of tropical spider lily (Hymenocallis littoralis) plants were grown in field soil in clear-plastic-wall open-top enclosures in the Sonoran Desert environment of central Arizona. It also increased the concentrations of five bulb constituents that have been demonstrated to possess anticancer and antiviral activities.

   • According to Noormi R (2012)

     Excerpt Gram positive bacteria (Micrococcus spp, Bacillus subtilis, Bacillus thuringiensis, Staphylococcus aureus), Gram negative bacteria Escherichia coli (normal), Escherichia coli (hospital strain) Pseudomonas aeruginosa, Salmonella spp, Proteus mirabilis, Klebsiella pneumoniae), & fungal strains (Candida albicans, Aspergillus niger). The screening of antimicrobial activity namely disk diffusion & minimum inhibitory concentration (MIC) were carried out using Hymenocallis littoralis (Jacq.) Salisb plant’s extracts with twelve (12) different parts of juvenile & flowering stages against twelve (12) microbes.

   • According to Anusha H (2016)

     Excerpt Hymenocallis littoralis (Jacq.) Salisb.

Further indications (including other extraction modes where applicable), dosages, precautions for use, and the <strong>full scientific references</strong> (complete records, not only the short excerpts above) are available in the complete monographic record in the Lapo v2 application.