Hyptis suaveolens (Lamélis) : medicinal properties in alcoholic extraction

Hyptis suaveolens (Lamélis, Lemon balm, Melisse) — family Lamiacées.

Scientific synonyms : Ballota suaveolens-L., Gnoteris cordata-Raf, Hyptis congesta-L, H graveolens-S, Marrubium indicum-Blanco, Mesosphaerum suaveolens-(L) Ktze, Schaueria suaveolens-(L.) Hassk.

Recognised external sources linked to this monograph: TRAMIL.

This database documents alcoholic (ethanol) extractions of active substances. Our monograph currently lists 20 indications in alcoholic extraction for this species. The Lapo v2 catalogue records 105 scientific references for this species (full detail in the application).

Important — scientific references on this public page: only a short excerpt of each cited source is shown (selected abstract sentences), kept in the original language of the publication (most often English), without translation. These excerpts are not the full article text and are not a complete bibliography. The full reference records and complete monographic detail are available in the Lapo v2 application (free 30-day trial).

1. 1

   Type II diabetes mellitus

   Plant part used: Sheet.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to Mishra SB (2011)

     Excerpt Methods: Hyptis suaveolens extract (HSE) 250 & 500 mg/kg body weight was administered orally to streptozotocin induced diabetes, once daily for 21 days. To evaluate the antihyperglycemic activity of leaves of Hyptis suaveolens using streptozotocin model.

   • According to Danmalam UH (2009)

     Excerpt Danmalam UH et al, ACUTE TOXICITY STUDIES & HYPOGLYCEMIC ACTIVITY OF THE METHANOL EXTRACT OF THE LEAVES OF HYPTIS SUAVEOLENS POIT.

   • According to Li R (2020)

     Excerpt This review aimed to provide a comprehensive overview of ethnobotanical uses, chemical constituents, posology, & toxicology of Hyptis suaveolens, & to address the significant medicinal benefits in order to promote its application. To date, pharmacological studies have demonstrated the significant activities of this plant that support uses such as antimicrobial, antidiabetic, antiulcer, & antiinflammatory.

   • According to Mishra P (2021)

     Excerpt Short conclusion: Hyptis suaveolens contains unique terpenoid metabolites like suaveolic acid, suaveolol, methyl suaveolate, beta-sitosterol, ursolic acid, & phenolic compound like rosamarinic acid, methyl rosamarinate that have potentiality to substitute the traditional drugs as therapeutic agent against the resistant & newly emerged bacterial and viral pathogens. The aim of the present study is to review the existence of medicinally important secondary metabolites and possible pharmacological and pharmacognostic importance of under-explored weed plant species Hyptis suaveolens (L.) Poit., to explore the potentiality of the plant for developing & designing the drugs for future.

2. 2

   Ulcerative colitis

   Plant part used: Aerial parts.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to Frota-Machado FD (2021)

     Excerpt In folk medicine Hyptis suaveolens (Lamiaceae) has been reported to relieve respiratory & gastrointestinal infections, indigestion, cold, pain, fever, cramps, skin diseases, gastric ulcer & inflammatory disorders. Nevertheless, only Hs-HexF was able to reduce colonic wall thickness, edema & diffuse inflammatory cell infiltration & to prevent GSH depletion in the acute model of ulcerative colitis.

   • According to Grassi P (2006)

     Excerpt The anti-inflammatory properties of these compounds could contribute to the antiphlogistic activity of extracts of Hyptis species & confirm the rational use of HS extracts in dermatological diseases. Separation & isolation of the two main compounds suaveolol & methyl suaveolate from leaves of chichinguaste (Hyptis suaveolens Poit., Lamiaceae) could be achieved by means ofrepeated column chromatography & repeated preparative thin layer chromatography.

   • According to Nayak PS (2001)

     Excerpt Particular attention has been given to antioxidant & anti-inflammatory, antibacterial & wound healing properties, insecticidal effects presented in this review such that the potential use of this plant either in pharmaceutics or as an agricultural resource can be evaluated. They are used as tonics, emmenagogues, diaphoretics, antispasmodics, burns & wounds, antimicrobial, antibacterial, antispasmodic, analgesic, anti-inflammatory, headaches, anticatarrhal, anticutaneous.

   • According to Bayata B (2020)

     Excerpt Hyptis suaveolens is an aromatic plant used in traditional medicine in Burkina Faso for management of various diseases including wounds & inflammatory diseases. suaveolens of which the major compounds identified are Sabinene 14.03%, β-Pinene 5.92%, Limonene 4.40%, Eucalyptol 12.78%, Trans-Oxide of Linalol 5.43%, β-Caryophyllene 11.27%, Germacrene-D 3.04% & Bicyclogermacrene 8.08%.

   • According to Li R (2020)

     Excerpt The extracts and phytochemicals isolated from the plants show considerable potential for medicinal exploitation & utilization, including antimitotic, antiproliferative, cytotoxic, antioxidant, anti-inflammatory, antibacterial, antifungal, antiviral, anti-secretory, hepatoprotective, insecticidal, and acaricidal activities. This review aimed to provide a comprehensive overview of ethnobotanical uses, chemical constituents, posology, & toxicology of Hyptis suaveolens, & to address the significant medicinal benefits in order to promote its application.

3. 3

   Fungal infection: Aspergillus niger & Micrococcus luteus

   Plant part used: Sheet.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to Mandal SM (2007)

     Excerpt It showed highest antifungal & antibacterial activity against Aspergillus niger & Micrococcus luteus, respectively. Steam distillation, petroleum ether, & ethanol extracts from Hyptis suaveolens leaves were evaluated for their antimicrobial activity in vitro.

   • According to Sanchez-Aguirre O (2020)

     Excerpt Hyptis suaveolens(L.) is a medicinally plant available in the south & southeast region of Mexico, Latin America & the south & west region of Africa. The results confirm the great potential of this species as an antioxidant & antibacterial representing the first contribution to the chemical & biological knowledge of HS from Mexican mountain range.

   • According to Kothandan S (2014)

     Excerpt Results: Aqueous & aqueous ethanolic extracts of Hyptis suaveolens exhibited partial inhibition to Asian strain of chikungunya virus. Methods: In vitro cytotoxicity assay of the lyophilized extracts was assessed in Vero cells for the determination of maximum nontoxic concentration and in vitro antiviral assay was evaluated by the inhibition of virus induced cytopathic effect.

   • According to Okonogi S (2005)

     Excerpt Volatile oil distilled from the overground part of Hyptis suaveolens was preliminary quality controlled by GC. The creams containing 30% w/w of oil in four selected bases were tested for their stability, antimicrobial activity & primary irritation test using Garamycin® cream (0.1% gentamicin) as a positive control.

   • According to Xu DH (2013)

     Excerpt To characterize chemical compositions of the oils from three Hyptis species & evaluate their potential antimicrobial, radical scavenging activities & toxicities against brine shrimp. Discussion & conclusions: The three Hyptis species oils possess strong antimicrobial activities & toxicities.

Further indications (including other extraction modes where applicable), dosages, precautions for use, and the <strong>full scientific references</strong> (complete records, not only the short excerpts above) are available in the complete monographic record in the Lapo v2 application.