Imperata cylindrica (Payôt) : medicinal properties in alcoholic extraction

Imperata cylindrica (Payôt) — family Poacées.

Scientific synonyms : IImperata angolensis-Fritsch, I arundinacea var. koenigii (Retz.) Benth, I thunbergia-(Retz)-Nees, Lagurus cylindricus-L, Saccharum cylindricum -L.) Lam., S koenigii-Retz., S laguroides-Pourr., S thunbergii-Retz..

This database documents alcoholic (ethanol) extractions of active substances. Our monograph currently lists 9 indications in alcoholic extraction for this species. The Lapo v2 catalogue records 60 scientific references for this species (full detail in the application).

Important — scientific references on this public page: only a short excerpt of each cited source is shown (selected abstract sentences), kept in the original language of the publication (most often English), without translation. These excerpts are not the full article text and are not a complete bibliography. The full reference records and complete monographic detail are available in the Lapo v2 application (free 30-day trial).

1. 1

   Type II diabetes mellitus

   Plant part used: Sheet.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to Suraya AA (2012)

     Excerpt The present study was carried out to determine the effect of ethanolic extract of commonly available Imperata cylindrica leaves on alloxan induced diabetic rats. The male Wistar rats (100-110gm) were fasted overnight before the intraperitoneal injection of alloxan monohydrate (100 mg/kg, i.p) prepared in the citrate buffer (0.1M, pH 4.5) for three consecutive days to produce diabetes.

   • According to Cui J (2012)

     Excerpt To study the effects of Imperata cylindrica polysaccharides on blood glucose & lipid in diabetic mice. Method: Diabetes was induced by intraperitoneal injection of streptozotocin in mice.

2. 2

   Cancer: adjuvant treatment of oral squamous cell carcinoma

   Plant part used: Sheet.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to Keshava R. (2016)

     Excerpt cylindrica using an oral squamous cell carcinoma cell line SCC-9 as an in vitro model system.

   • According to Orliando Roeslan M (2021)

     Excerpt Squamous cell carcinoma (SCC) is classified as the most common type of oral cancer up to 90% of all malignant neoplasm in the oral cavity. Purpose: The study aims to determine the effect of IC leaf extract on the proliferation & migration of human oral squamous carcinoma-3 (HSC-3) cell lines.

   • According to Paul N (2021)

     Excerpt Imperata cylindrica is traditionally used to cure several diseases including cancer, wounds, & hypertension. In conclusion, IC-MeOH is a rich source of cytotoxic metabolites that inhibits human cervical cancer proliferation via apoptosis & cell cycle arrest.

   • According to Paul N (2020)

     Excerpt The aim of this study was to assess the acute & sub-chronic oral toxicity of methanol root extract of Imperata cylindrica. the cytotoxicity of the root's methanol extract of Imperata cylindrica (ICR).

   • According to Paul N (2021)

     Excerpt Imperata cylindrica is a medicinal spice traditionally used in the treatment of hypertension & cancer. After the genome-wide transcriptome analysis, we found that important genes involved in cancer progression & metastasis of cervical cancer, that is, CD24 and TIMP-4 were significantly downregulated & upregulated, respectively.

3. 3

   Hypercholesterolaemia

   Plant part used: Root.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to Khaerunnisa S (2020)

     Excerpt The in vivo tests showed that the ethyl acetate fraction of IC reduced total cholesterol & LDL levels more effectively than the ethanol extract, but did not affect HDL levels in rats with hypercholesterolemia. The fraction of ethyl acetate administered at 15 mg/200 g BW was capable of lowering the total cholesterol levels significantly (P=0.002) & lowered LDL levels (P=0.006) but was unable to increase HDL levels (P=0.190).

   • According to Maryati M (2021)

     Excerpt Imperata cylindrica is a well-known species of perennial rhizomatous grass native to tropical South East Asia, which possesses extensive medicinal value. PubMed & Scopus databases were used to search for suitable keywords such as IC cogongrass, hypolipidemic, triglyceride, cholesterol, low-density lipoprotein (LDL), & very-low-density lipoprotein (VLDL).

   • According to Robianto S (2019)

     Excerpt The results showed a significant shortening of the estrus phase in 90 & 115 mg/BW but not significant in glucose & cholesterol serum level during pre & post CGG treatment (p<0.05).

   • According to Paul N (2020)

     Excerpt The aim of this study was to assess the acute & sub-chronic oral toxicity of methanol root extract of Imperata cylindrica. the cytotoxicity of the root's methanol extract of Imperata cylindrica (ICR).

   • According to Anggraeni N (2017)

     Excerpt Pretreated group was further divided into two groups that received different dose of Imperata cylindrica L. Imperata cylindrica L.

Further indications (including other extraction modes where applicable), dosages, precautions for use, and the <strong>full scientific references</strong> (complete records, not only the short excerpts above) are available in the complete monographic record in the Lapo v2 application.