Ipomea batatas (Sweet potato) : medicinal properties in alcoholic extraction

Ipomea batatas (Sweet potato, sweet potato (yellow and purple varieties), Patat dous, patate douce (variété jaune & pourpre)) — family Convolvulacées.

Recognised external sources linked to this monograph: TRAMIL.

This database documents alcoholic (ethanol) extractions of active substances. Our monograph currently lists 14 indications in alcoholic extraction for this species. The Lapo v2 catalogue records 145 scientific references for this species (full detail in the application).

Important — scientific references on this public page: only a short excerpt of each cited source is shown (selected abstract sentences), kept in the original language of the publication (most often English), without translation. These excerpts are not the full article text and are not a complete bibliography. The full reference records and complete monographic detail are available in the Lapo v2 application (free 30-day trial).

1. 1

   Cancer: adjuvant treatment of colorectal, neck, breast and lung cancer

   Plant part used: Tuber.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to Wayan S (2010)

     Excerpt The activities of the anticancer are evaluated from cytotoxic & antiproliferative effects on cell line breast cancer T47D. Ethanol extracts purple sweet potatoes showed antiproliferative activitiesonT47D breast cancer cells in 2 4,48,72 hours incubation in concentrations 500;1,000; &2,000 􏰀g/ml; thoseare35,700;29,800;25,500 cells (24 hours);72,500;60,300; 52,600 cells (48 hours);149,500;122,600;107,300 cells (72 hours).

   • According to Sugata M (2015)

     Excerpt Anticancer activities of these extracts were displayed through their ability to inhibit the growth of cancer cell lines, such as MCF-7 (breast cancer), SNU-1 (gastric cancer), & WiDr (colon adenocarcinoma), in concentration- & time-dependent manner. Further studies also revealed that SP extracts could induce apoptosis in MCF-7 & SNU-1 cancer cells through extrinsic & intrinsic pathway.

   • According to Huang D (2004)

     Excerpt The aim of this study is to examine possible antioxidant & antiproliferative activities of the different extracts from sweet potato (Ipomoea batatas [L.] Lam ‘Tainong 57’) organs. The antiproliferative activities of sweet potato were studied in vitro using human lymphoma NB4 cells, & the following results were found: water extract of vein had the highest antiproliferative activity with an EC50 of 449.6 ± 27.73 μg/mL, followed by water extract of storage root, water extract of leaf, ethanol extract of storage root, & ethanol extract of leaf.

   • According to Oluyori AP (2019)

     Excerpt The study highlights the peel of I batatas as a rich dietary source of natural anticancer molecules which may be developed into nutraceuticals or serve as new leads in anticancer therapy. 25 liters of 95% ethanol percolated the pulverized I batatas to give 112 g of the ethanolic extract (IB A001) after concentration using rotary evaporator at 50°C.

   • According to Dewijanti D (1904)

     Excerpt Antioxidant activity, phenolic & total flavonoids from sweet potato ethanol extract (Ipomea batatas L.) of different varieties (white, yellow, orange & purple) were studied. Sweet potato leaves have been used for numerous oxidative-associated diseases such as cancer, allergy, aging, HIV & cardiovascular.

2. 2

   Osteoarthritis, arthritis, rheumatism, oedema

   Plant part used: Sheet.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to Sugata M (2015)

     Excerpt They even exhibited anti-inflammatory activities by suppressing the production of NO & proinflammatory cytokines, such as NF-κβ, TNF-α, & IL-6, in LPS-induced macrophage cells. However, a few reports are available concerning its anti-inflammatory & anticancer properties.

   • According to Tasya SC (2023)

     Excerpt NSAID (Non-Steroid Anti-Inflammatory Drugs) & AIS (Antiinflammatory Steroids) have been used in Indonesia to treat inflammation but have side effects on the body. IB) leaves are scientifically proven to have anti-inflammatory activity as evidenced by the presence of compounds that have anti-inflammatory effects and can be developed into products for inflammation.

   • According to Shrivastava AK (2023)

     Excerpt This study aimed to evaluate the antioxidant, antiarthritic, & anti-inflammatory properties of extracts from the leaves of twelve different medicinal plants in Nepal. In conclusion, this study demonstrated the twelve leaf extracts' significant antioxidant, antiarthritic, & anti-inflammatory activities.

   • According to Ludvik B (2008)

     Excerpt The present study was designed to further evaluate its mode of action on insulin sensitivity over an extended period of time as well as the effects on fibrinogen and other markers of low-grade inflammation. The extract of the white-skinned sweet potato Ipomoea batatas (Caiapo) has been shown to ameliorate glucose control by improving insulin sensitivity in patients with type 2 diabetes mellitus.

   • According to Kang H (2014)

     Excerpt Increased production of inflammatory mediators such as iNOS, COX-2 & TNF-α (p < 0.01 & p < 0.001 at 100 & 200 μg/ml, respectively) was attenuated by IBE concentration-dependently. To evaluate the protective effects of purple sweet potato (Ipomoea batatas Linn, Convolvulaceae) extract (IBE) in stimulated BV-2 microglial cells & its antioxidant properties.

3. 3

   Peptic ulcer

   Plant part used: Tuber.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to Sathish R (2012)

     Excerpt The I batatas roots possess anti-ulcer activity as evidenced by its significant inhibitory effects on PL & CRS induced ulcers. Peptic ulcer is one of the most prévalent gastrointestinal disorder, commonly occurs in developed countries.

   • According to Panda V (2012)

     Excerpt Panda V et al, Antiulcer activity of Ipomoea batatas tubers (sweet potato), Functional Foods in Health & Disease 2012, 2(3):48-61-.

   • According to Rezeki S (2017)

     Excerpt Leaves Extract on Percentage Healing of Traumatic Ulcer in Oral Mucosa (Rattus Norvegicus Strain Wistar).

   • According to Hermès D (2013)

     Excerpt Hermès D et al, In vivo wound healing & antiulcer properties of white sweet potato (Ipomoea batatas) Jl of Advanced Res, 4 (4) :411–5, 2013,.

   • According to Sugata M (2015)

     Excerpt Anticancer activities of these extracts were displayed through their ability to inhibit the growth of cancer cell lines, such as MCF-7 (breast cancer), SNU-1 (gastric cancer), & WiDr (colon adenocarcinoma), in concentration- & time-dependent manner. They even exhibited anti-inflammatory activities by suppressing the production of NO & proinflammatory cytokines, such as NF-κβ, TNF-α, & IL-6, in LPS-induced macrophage cells.

Further indications (including other extraction modes where applicable), dosages, precautions for use, and the <strong>full scientific references</strong> (complete records, not only the short excerpts above) are available in the complete monographic record in the Lapo v2 application.