Jatropha curcas (White doctor) : medicinal properties in alcoholic extraction

Jatropha curcas (White doctor, Green Ortolan, Ortolan seed, Mèdsiyen-blan, Grenn-Zôtolan, Medeciner blanc, Graine-à-Ortolan) — family Euphorbiacées.

Scientific synonyms : Castiglionia lobata-R &P, Curcas indica-R, Jatropha curcas var, rufa McVaugh, J edulis- S, J Yucatensis-B, Manihot curcas-(L)-Crantz..

Recognised external sources linked to this monograph: TRAMIL and French Pharmacopoeia.

This database documents alcoholic (ethanol) extractions of active substances. Our monograph currently lists 12 indications in alcoholic extraction for this species. The Lapo v2 catalogue records 94 scientific references for this species (full detail in the application).

Important — scientific references on this public page: only a short excerpt of each cited source is shown (selected abstract sentences), kept in the original language of the publication (most often English), without translation. These excerpts are not the full article text and are not a complete bibliography. The full reference records and complete monographic detail are available in the Lapo v2 application (free 30-day trial).

1. 1

   Type 2 diabetes mellitus

   Plant part used: Sheet.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to Ogunjinmi OE (2023)

     Excerpt Vernonia amygdalina, Senna alata, Jatropha curcas, & Grewia pubescens are important plants with immense value. While the least content of all was found in the extracts of Jatropha curcas.

2. 2

   Cirrhosis, hepatitis, fatty liver disease

   Plant part used: Sheet.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to Ochekuwu U (2015)

     Excerpt this study, ethanol leaf extract of Jatropha curcas were selected for their hepatoprotective activity on experimentally induced hepatotoxicity in rats. Wistar strain albino rats were used for assessment of hepatoprotective activity & hepatotoxicity was induced by the administration of chloroform.

   • According to Nwala (2013)

     Excerpt The safety of the use of leaf extract of Jatropha curcas plant in different groups of Wistar albino rats at different doses was investigated. The animals were sacrificed & the effect of the leaf extract on blood biochemistry & histopathological examination of the kidney & liver tissues were assessed using standard techniques.

   • According to Abdu-Aguye I (1985)

     Excerpt The seeds of Jatropha curcas L. Post-mortem studies in this case showed widespread haemorrhages involving the colon, lungs as well as infarction of the liver.

   • According to Shuit SH (2010)

     Excerpt Biodiesel from Jatropha curcas L.

   • According to Ugbogu AE (2013)

     Excerpt This study investigated the nutritional and chemical properties of Jatropha curcas seed oil from Abia State, Nigeria using standard analytical methods. These results suggest that J curcas seed oil may not be suitable for human consumption except it is subjected to detoxification & purification before use, but may be suitable for Industrial purposes such as production of soaps, paints & lubricants.

3. 3

   Fungal infection: Fusarium oxysporum, Pythium aphanidermatum, Lasiodiplodia theobromae, Curvularia lunata, Fusarium semitectum, Colletotrichum capsici, Colletotrichum gloeosporioides

   Plant part used: Seed.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to Saetae D (2010)

     Excerpt curcas seed cake showed antifungal activities against important phytofungal pathogens: Fusarium oxysporum, Pythium aphanidermatum, Lasiodiplodia theobromae, Curvularia lunata, Fusarium semitectum, Colletotrichum capsici & Colletotrichum gloeosporioides. Phorbol ester extraction was carried out from Jatropha curcas seed cake, a Byproduct from the biodiesel fuel Industry.

   • According to El Din Gomaa E (2016)

     Excerpt Phytochemical screening (saponins, tannins, steroids, alkaloids, flavonoids, phenols & glycosides) of four medicinal plant seeds (Jatropha curcas, Simmondsia chinensis, Moringa oleifera & Datura metel) extracted by aqueous, ethanol & Folch solvents, were examined for their antimicrobial activity against three types of plant pathogenic fungi namely; Botrytis cinerea, Fusarium oxysporum & Rhizoctonia solani, in addition to four types of bacteria, namely; Bacillus cereus, Staphylococcus aureus, Ralstonia solanacearum & Pseudomonas aeruginosa using disc diffusion paper. Results revealed that different concentrations of aqueous extracts were more effective against bacterial activity compared to fungal activity, except for D.

   • According to Dahake R (2013)

     Excerpt In the current study, potentially drug-resistant HIV was isolated & previously unreported anti-viral activity of Jatropha curcas leaf extracts was assessed. Post-infection (4 isolates) interaction studies showed IC50 values ranging from 0.0255-0.4137 mg/mL & 0.00073-0.1278 mg/mL for Aqueous & Methanolic Extracts respectively & pre- infection (1 isolate) interaction studies showed 100% inhibition by Methanolic & 97.19% inhibition by Aqueous Extract at 25 mg/mL each.

   • According to Author (n.d.)

     Excerpt Our results provide the information which shows the potential of Jatropha extracts in the treatment of influenza A (H1N1) virus infection. Jatropha curcas is known for various medicinal uses.

   • According to Dakpogan HB (2019)

     Excerpt The anticoccidial activity of Phyllanthus amarus (Hurricane weed), Jatropha curcas (purging nut) & Piliostigma thonningii (monkey bread) was tested on seventy-five Eimeria tenella infected Isa-brown male day-old chicks in a completely randomized design as an alternative measure of controlling coccidiosis. The first, second & third groups received, the decoction of Phyllanthus amarus, Jatropha curcas & Piliostigma thonningii, ad libitum respectively for five days post-inoculation as drinking beverage.

Further indications (including other extraction modes where applicable), dosages, precautions for use, and the <strong>full scientific references</strong> (complete records, not only the short excerpts above) are available in the complete monographic record in the Lapo v2 application.