Litchi sinensis (Lychee) : medicinal properties in alcoholic extraction

Litchi sinensis (Lychee, Litchi) — family Sapindacées.

Scientific synonyms : Euphoria dydima-Blanco, Nephelium chinense-(Sonn)-D, N litchi-Steud.

This database documents alcoholic (ethanol) extractions of active substances. Our monograph currently lists 12 indications in alcoholic extraction for this species. The Lapo v2 catalogue records 96 scientific references for this species (full detail in the application).

Important — scientific references on this public page: only a short excerpt of each cited source is shown (selected abstract sentences), kept in the original language of the publication (most often English), without translation. These excerpts are not the full article text and are not a complete bibliography. The full reference records and complete monographic detail are available in the Lapo v2 application (free 30-day trial).

1. 1

   Cancer; adjuvant treatment of liver, breast, nasopharyngeal and lung cancer

   Plant part used: Flower.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to Punia S (2021)

     Excerpt The review also unfolds bioactivities (anticancer, neuro-protective, antioxidant, anti-viral, anti-microbial, hepato-protective, lipid lowering) of the litchi seed extract (LSE). Scope & approach: This review article firstly narrates the nutritional composition of the litchi seed which includes its phenolic compounds, bioactive & starchy polysaccharides (40.7%), proteins (4.93%), oil content (3.2%), & minerals.

   • According to Wang X (2006)

     Excerpt Our findings showed that LFP extract exhibited potential anticancer activity against hepatocellular carcinoma in vitro & in vivo through proliferating inhibition & apoptosis induction of cancer cells. The purpose of this study is to confirm the anticancer activity of LFP extract against hepatocellular carcinoma in vitro & in vivo, and to elucidate the mechanism of its activity.

   • According to Lin N (2008)

     Excerpt CONCLUSION: Semen Litchi can inhibit the growth of S180 & EAC tumor cells in vitro & in vivo, & its antitumor effect is related to its ability to promote apoptotic of tumor cells. EAC, S180 & hepatic carcinoma suspensions were diluted respectively with normal saline in a ratio of 1∶1 for the preparation of tumor-bearing ascites suspension.

   • According to Xiao L (2007)

     Excerpt CONCLUSION: The anti-tumor activity of Semen Litchi is possibly associated to the elevated bcl-2 expression level in rats & its promotion on the apoptosis of carcinoma cells,. To establish hepatic carcinoma-bearing mouse model & to study the effect of the aqueous extract of Semen Litchi on the growth of solid tumor in mouse model.

   • According to Thiesen LC (2018)

     Excerpt Further, CCl4evokes an increase in serum alanine aminotransferase (ALT), tumor necrosis factor (TNF) & interleukin-6 (IL-6) levels in hepatic tissue. chinensis extract were able to restore the viability of cells treated with CCl4 at all concentrations evaluated, reduced the inflammatory parameters, TNF & IL-6, reestablished hepatic tissue morphology & did not induce acute toxicological alterations.

2. 2

   Hepatitis, fatty liver, cirrhosis

   Plant part used: Sheet.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to Punia S (2021)

     Excerpt The review also unfolds bioactivities (anticancer, neuro-protective, antioxidant, anti-viral, anti-microbial, hepato-protective, lipid lowering) of the litchi seed extract (LSE). Scope & approach: This review article firstly narrates the nutritional composition of the litchi seed which includes its phenolic compounds, bioactive & starchy polysaccharides (40.7%), proteins (4.93%), oil content (3.2%), & minerals.

   • According to Xiao J (2017)

     Excerpt The ethanol-induced hepatic steatosis & increases of triglyceride levels in the serum & liver were ameliorated by L-LPPE supplementation but aggravated by H-LPPE supplementation. Collectively, LPPE showed biphasic effects on ethanol-induced liver injury in mice, indicating that a moderate intake of LPPE or Litchi pulp could be useful for the prevention & control of alcoholic liver disease,.

   • According to Xiao J (2017)

     Excerpt LPPE supplementation significantly alleviated hepatic steatosis, suppressed serum aspartate aminotransferase activity,& decreased triglyceride levels in serum & liver. Our previous studies found lychee pulp phenolic extract (LPPE) exerted protective effect against ALD partly by inhibiting fatty acid β-oxidation, & phenolic-rich lychee pulp extract improved restraint stress-induced liver injury by inhibiting mitochondrial dysfunction.

   • According to Souza MG (2007)

     Excerpt Souza MG et al, Hepatoprotective Activity of Fruit Pulp Extract of Litchi chinensis Sonner on Carbon tetrachloride Induced Hepatotoxicity in albino Rats the Internet Journal of Alter Med, 4: 1, 2007,.

   • According to Basu S (2012)

     Excerpt In the present study, the chloroform & methanol extracts from Litchi chinensis leaf were evaluated for their protective effects on paracetamol-induced liver damage in Wistar albino rats. All biochemical observations indicated that both the test extracts exerted significant hepatoprotective efficacy against paracetamol-induced hepatic damage in rats.

3. 3

   Bacterial infection: Escherichia coli

   Plant part used: Trunk bark.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to Deshwal VK (2012)

     Excerpt Main focus of present study was to screen the UTI patients, classification of patient on the basis of sex, age and antimicrobial activity of different ethanol, aqueous extracts of bark of Litchi chinensis against Escherichia coli. Result suggested that Ethanol extract of Litchi chinensis showes more antibacterial activity as compared to aqueous extract, & norfloxacin against E.

   • According to SHAHWAR D (2010)

     Excerpt SHAHWAR D et al, Comparative study on the antioxidant&d antimicrobial activities of stem-bark extract of Litchi chinensis & its organic fractions, J of the Chem Society of Pakistan, 32 :3 (2010),.

   • According to Shafi Bhat R (2014)

     Excerpt Shafi Bhat R et al, antimicrobial activity of Litchi chinensis & Nephelium lappaceum aqueous seed extracts against some pathogenic bacterial strains, J of King Saud Univ – Sci, 26(1) :79–8, 2014,.

   • According to Upadhyaya DC (2017)

     Excerpt Crude extracts and pure compounds isolated from L C exhibited noteworthy anti-oxidant, anti-cancer, anti-inflammatory, antimicrobial, anti-viral, anti-diabetic, anti-obesity, hepato-protective & immunomodulatory activities. Litchi chinensis has been widely used as anti-cancer, antiseptic, hypoglycemic, antihyperlipidemic, antiplatelet, antitussive, analgesic, anti-pyretic, diuretic, anti-viral, and hemostatic activities.

   • According to Emanuele S (2017)

     Excerpt Due to its biological activities, the fruit is becoming increasingly known & deserves attention not only for its edible part, the pulp, but also for its peel & seed that contain beneficial substances with antioxidant, cancer preventive, antimicrobial, & anti-inflammatory functions. Although literature demonstrates the biological activity of Litchi components in reducing tumor cell viability in in vitro or in vivo models, data about the biochemical mechanisms responsible for these effects are quite fragmentary.

Further indications (including other extraction modes where applicable), dosages, precautions for use, and the <strong>full scientific references</strong> (complete records, not only the short excerpts above) are available in the complete monographic record in the Lapo v2 application.