Mentha piperata (Spiced lanmant) : medicinal properties in alcoholic extraction

Mentha piperata (Spiced lanmant, Peppermint, Lanmant pwavré, Menthe poivrée) — family Lamiacées.

Scientific synonyms : Mentha citrata-Ehrh.

Recognised external sources linked to this monograph: TRAMIL and French Pharmacopoeia.

This database documents alcoholic (ethanol) extractions of active substances. Our monograph currently lists 16 indications in alcoholic extraction for this species. The Lapo v2 catalogue records 134 scientific references for this species (full detail in the application).

Important — scientific references on this public page: only a short excerpt of each cited source is shown (selected abstract sentences), kept in the original language of the publication (most often English), without translation. These excerpts are not the full article text and are not a complete bibliography. The full reference records and complete monographic detail are available in the Lapo v2 application (free 30-day trial).

1. 1

   Cancer: adjuvant treatment for squamous cell carcinoma of the larynx

   Plant part used: leaf.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to Gangai-Abirami SK (2014)

     Excerpt Ethanolic extracts of Mentha Piperata, Ocimum basilicum & Coleus aromaticus were studied for the in-vitro cytotoxicity against Human Laryngeal epidermoid carcinoma (Hep-2 cell lines). The findings of the present investigation demonstrated that M Piperata significantly suppresses growth & induces apoptosis in Hep-2 cell lines.

   • According to Mahendran G (2020)

     Excerpt × piperita for biological effects such as anti‐oxidant, anti‐microbial, anti‐viral, anti‐inflammatory, biopesticidal, larvicidal, anticancer, radioprotective effect, genotoxicity & anti‐diabetic activity have been ascribed. Peppermint (Mentha × piperita L) is a perennial, glabrous & strongly scented herb belongs to the family Lamiaceae.

   • According to Abedinpour N (2021)

     Excerpt The EO anticancer activity was evaluated at various incubation periods (24, 48, and 72 h) against three human breast cancer cell lines. In this study, constituents of Mentha piperita essential oil were identified using GC-MS analysis with five major ingredients of menthol (31.0%), menthone (22.1%), camphane (7.0%), menthofuran (6.0%), & iso-menthone (5.8%).

   • According to Dolghi A (2022)

     Excerpt The aim of the present study was to investigate the M_EO & R_EO in terms of chemical composition, antioxidant, antimicrobial, & cytotoxic effects in a colorectal cancer cell line-HCT 116. (R_EO) essential oils are well-known for their biological effects (antimicrobial, antioxidant, anti-inflammatory & cytotoxic in different cancer cells), but their potential as complementary treatment in colorectal cancer is underexplored. (2017) — excerpt: The objective of this study is to investigate the antiviral, anti-inflammatory, & antioxidant effects of the ethanol extract of Mentha piperita L. The levels of key pre-inflammatory mediators & cytokines including nitric oxide (NO), tumor necrosis factor alpha (TNF-α), interleukin (IL)-6, & prostaglandin E2 (PGE2) were determined.

2. 2

   Bacterial infection: Klebsiella pneumoniae, Staphylococcus aureus and Escherichia coli

   Plant part used: leaf.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to Qomariyah M (2021)

     Excerpt The purpose of this study was to determine the combined effect of the ethanolic extract of MP & amikacin against Klebsiella pneumonia, Staphylococcus aureus, & Escherichia coli as well as the compounds contained in the ethanolic extract of MP lleaves. The results showed a synergistic effect with the largest inhibition zone diameter at a ratio of 25:75 at a concentration of 200 mg/mL, which was 36.25±2.5 mm on K pneumonia bacteria.

   • According to Sujana P (2013)

     Excerpt The antibacterial potential of six extracts from leaf, stem & root of MP against pathogenic bacteria such as Bacillus subtilis, Streptococcus pneumonia, Staphylococcus aureus, Escherichia coli, Proteus vulgaris & Klebsiella pneumonia were evaluated by agar well diffusion method. The leaf extract activity being more on B subtilis, S aureus & P vulgaris than E coli, S pneumonia & K pneumonia.

   • According to Ertuk O (2011)

     Excerpt Eleven ethanolic extracts from spices of Melissa officinalis(FR:FE), Mentha piperita((Se), Laurus nobilis(Fe), Rhus coriaria, Dianthus coryophyllum, Piper nigrum(Se), Capsicum annum (Fr), Juniperus oxycedrus, Erica arborea, Colutea arborescens, & Cuminum cyminum(Fr) collected from various regions of Turkey & local markets were assayed for the in vitro antibacterial activity against 3 Gram-positive (Bacillus subtilis, Staphylococcus aureus & S. epidermidis) & 2 Gram-negative bacteria (Escherichia coli & Pseudomonas aeruginosa), using agar dilution methods.

   • According to Andogan BC (2002)

     Excerpt Escherichia coli (ATTC 25922), Staphylococcus aureus (ATCC 25923) & Pseudomonas aeruginosa (ATTC 27853 were used as standard test bacterial strains. Or onites recorded antimicrobial activity against all test bacteria, & was strongest against Staphylococcus aureus.

   • According to Sanei-Dekordi A (2022)

     Excerpt Moreover, the growth of Escherichia coli é Staphylococcus aureus after treatment with 5000 µg/mL of nanogel containing M. piperita essential oil could be introduced for further investigation against other mosquitoes & bacterial species.

3. 3

   Fungal infection: Aspergillus niger, Candida albicans

   Plant part used: seed.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to Ertuk O (2011)

     Excerpt In addition, their possible toxicity to Candida albicans & Aspergillus niger was determined, using both agar dilution & disc-diffusion methods. Eleven ethanolic extracts from spices of Melissa officinalis(FR:FE), Mentha piperita((Se), Laurus nobilis(Fe), Rhus coriaria, Dianthus coryophyllum, Piper nigrum(Se), Capsicum annum (Fr), Juniperus oxycedrus, Erica arborea, Colutea arborescens, & Cuminum cyminum(Fr) collected from various regions of Turkey & local markets were assayed for the in vitro antibacterial activity against 3 Gram-positive (Bacillus subtilis, Staphylococcus aureus & S.

   • According to Raghavan R (2018)

     Excerpt The three microbial strains, i.e., Streptococcus mutans, Aggregatibacter actinomycetemcomitans, & Candida albicans were used as microbiological materials. The study aims to assess the Mentha piperita aqueous leaf extract’s effectiveness against oral pathogens.

   • According to Yadegarinia D (2006)

     Excerpt The oils had good to excellent antimicrobial activities against Escherichia coli, Staphylococcus aureus & Candida albicans with the oil of M. GC-MS analysis of essential oils of Iranian Mentha piperita & Myrtus communis extracted by hydrodistillation lead to identification of 26 & 32 compounds, respectively.

   • According to Tampieri MP (2005)

     Excerpt By studying the efficacy of essential oils against different pathogenic mycetes, we have evaluated the in-vitro inhibiting activity of some EOs & their main constituents against a strain of Candida albicans. The essential oils of Origanum vulgare, Satureja montana, Mentha piperita, Cinnamomum verum, Cymbopogon flexuosus showed maximum inhibitory activity (MIC = 500 ppm) after 7 days.

   • According to Reddy DN (2019)

     Excerpt E shows significant antibacterial (S aureus, Micrococcus flavus, Bacillis subtilis, Salmonella Enteridis) & antifungal activity(Alternantaria Alternaria, Aspergillus fumigates, Fusarium tabacinum, F oxysporum, penicillium sp,.

Further indications (including other extraction modes where applicable), dosages, precautions for use, and the <strong>full scientific references</strong> (complete records, not only the short excerpts above) are available in the complete monographic record in the Lapo v2 application.