Murraya koenigii (Kaloupilé) : medicinal properties in alcoholic extraction

Murraya koenigii (Kaloupilé, karouvalpilaï) — family Rutacées.

Scientific synonyms : Bergera koenigii-L.

This database documents alcoholic (ethanol) extractions of active substances. Our monograph currently lists 27 indications in alcoholic extraction for this species. The Lapo v2 catalogue records 226 scientific references for this species (full detail in the application).

Important — scientific references on this public page: only a short excerpt of each cited source is shown (selected abstract sentences), kept in the original language of the publication (most often English), without translation. These excerpts are not the full article text and are not a complete bibliography. The full reference records and complete monographic detail are available in the Lapo v2 application (free 30-day trial).

1. 1

   Diabetic cardiomyopathy: prevention of cardiac fibrosis

   Plant part used: leaf.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to Zou J (2021)

     Excerpt However, no study has determined whether the total flavonoids of MK (TFMP) has preventive effects on diabetic cardiomyopathy (DCM). Diabetic rats showed serious histological changes & increased levels of cardiac function markers.

   • According to Zou J (2014)

     Excerpt This study was designed to evaluate the effects of total flavonoids extracted from the leaves of Murraya paniculata (L.) Jack (TFMP) on diabetic nephropathy. High fat diet & streptozotocin-induced diabetic rats were treated with the TFMP (35 or 70 mg/kg) for 13 weeks.

   • According to VINUTHAN M. (2004)

     Excerpt The effect of daily oral administration of aqueous extract (600 mg/kg b.wt.) and methanol extract (200 mg/kg b.wt.) of Murraya koenigii Spreng leaves for a period of eight weeks was studied on blood glucose & plasma insulin level in alloxan-induced diabetic rats.

   • According to -Husna F (2018)

     Excerpt The present study aims to investigate whether the antihyperglycemic effect of Murraya koenigii is mediated by antioxidant properties & insulin mimetic effect. Methods: Thirty Spraque-Dawley rats were induced hyperglycemia by streptozotocin & nicotinamide (STZ-NA).

   • According to Paul S (n.d.)

     Excerpt To delineate whether aqueous (AEM) & 50% methanol (MEM) leaf extracts have immunomodulatory properties to regulate oxidative stress metabolism & fight against the adverse effect of diabetes in diabetic mice. Materials & methods: Alloxan-induced diabetic mice were received oral doses of extract (≥ 200 mg/kg body weight).

2. 2

   Type II diabetes mellitus

   Plant part used: leaf.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to VINUTHAN M. (2004)

     Excerpt The effect of daily oral administration of aqueous extract (600 mg/kg b.wt.) and methanol extract (200 mg/kg b.wt.) of Murraya koenigii Spreng leaves for a period of eight weeks was studied on blood glucose & plasma insulin level in alloxan-induced diabetic rats.

   • According to Zou J (2021)

     Excerpt However, no study has determined whether the total flavonoids of MK (TFMP) has preventive effects on diabetic cardiomyopathy (DCM). Diabetic rats showed serious histological changes & increased levels of cardiac function markers.

   • According to -Husna F (2018)

     Excerpt The present study aims to investigate whether the antihyperglycemic effect of Murraya koenigii is mediated by antioxidant properties & insulin mimetic effect. Methods: Thirty Spraque-Dawley rats were induced hyperglycemia by streptozotocin & nicotinamide (STZ-NA).

   • According to Paul S (n.d.)

     Excerpt To delineate whether aqueous (AEM) & 50% methanol (MEM) leaf extracts have immunomodulatory properties to regulate oxidative stress metabolism & fight against the adverse effect of diabetes in diabetic mice. Materials & methods: Alloxan-induced diabetic mice were received oral doses of extract (≥ 200 mg/kg body weight).

   • According to Tembhurne SV (2012)

     Excerpt To evaluate the hypoglycemic & anti-obesity activities of of Murraya koenigii leaves. This fact could support their use by the diabetes patient for controlling body weight as well as maintains the glycemic level.

3. 3

   Cirrhosis, hepatitis, fatty liver disease

   Plant part used: leaf. Mentioned synergistic association: Phyllanthus niruri-feuille.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to Shah P (2015)

     Excerpt The present study is an attempt to determine the combined hepatoprotective potential of hydroethanolic leaf extracts of Murraya koenigii & Phyllanthus niruri against paracetamol (PCM) & ethanol-induced toxicity in human hepatoma HepG2 cell line. niruri, & silymarin during both prophylactic and curative studies.

   • According to Debosree G (2012)

     Excerpt Protective effect of aqueous leaf extract of Murraya koenigii against lead induced oxidative stress in rat liver, heart & kidney: A dose response study.

   • According to Parimi BN (2014)

     Excerpt Parimi BN et al, the protective effect of Murraya koenigii leaves against carbon tetra chloride-induced hepatic damage in rats J of Coastal Life Med, 2014; 2(4): 313-318,.

   • According to -Tan MA (2022)

     Excerpt Murraya koenigii (Rutaceae) is utilized in Ayurvedic medicine for various ailments. Pharmacological studies evidenced its potential antioxidant, anti-inflammatory, anticancer, hepatoprotective, immunomod-ulatory, antimicrobial, & neuroprotective activities, among others.

   • According to Pande MS (2009)

     Excerpt Pande MS et al, Hepatoprotective activity of Murraya koenigii Linn bark.

Further indications (including other extraction modes where applicable), dosages, precautions for use, and the <strong>full scientific references</strong> (complete records, not only the short excerpts above) are available in the complete monographic record in the Lapo v2 application.