Myrtus communis (Myrte) : medicinal properties in alcoholic extraction

Myrtus communis (Myrte) — family Myrtacées.

Recognised external sources linked to this monograph: French Pharmacopoeia.

This database documents alcoholic (ethanol) extractions of active substances. Our monograph currently lists 17 indications in alcoholic extraction for this species. The Lapo v2 catalogue records 126 scientific references for this species (full detail in the application).

Important — scientific references on this public page: only a short excerpt of each cited source is shown (selected abstract sentences), kept in the original language of the publication (most often English), without translation. These excerpts are not the full article text and are not a complete bibliography. The full reference records and complete monographic detail are available in the Lapo v2 application (free 30-day trial).

1. 1

   Cancer: adjuvant treatment for colorectal, liver, breast and uterine cancer

   Plant part used: Sheet.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to -Sen A (2016)

     Excerpt The aim of our study was to investigate the antifibrotic & antioxidant effects of Myrtus communis subsp. communis (MC) extract against liver injury & fibrosis occurring in rats with biliary obstruction.

   • According to HUANG ZQ (1935)

     Excerpt HUANG ZQ et al, Discussion on traditional Chinese medicine properties of Myrtus communis leaves based on literature analysis & Chinese medicine theory, Zhongguo Zhong Yao Za Zhi, 46(8) :1935-42, 2021-Abtract: Myrtus communis is a traditional medicinal aromatic plant in the Mediterranean. The channel tropisms of MC leaves included lung, liver, & large intestine, with functions of detoxifying, resolving a mass, & insecticide.

   • According to Jabri MA (2018)

     Excerpt Myrtus communis L., known as common myrtle, is native to Southern Europe, North Africa, & Western Asia.

   • According to Mir MA (2024)

     Excerpt Additionally, the extract exhibited potent anticancer effects against diverse cancer cell lines of the breast (MCF-7), liver (HepG2), cervix (HeLa), & colon (HCT116) (IC50 for HCT116: 83 ± 2.5, HepG2: 53.3 ± 0.6, MCF-7: 41.5 ± 0.6, & HeLa: 33.3 ± 3.6) by apoptosis after arresting the cells in the G1 phase of the cell cycle. A well-known medicinal herb, Myrtus communis is an evergreen fragrant plant native to the Mediterranean region that has been used for ages in traditional medicine around the world.

   • According to Belhacene S (n.d.)

     Excerpt The pharmacokinetic profiles of the active molecules were determined using the SwissADME website, followed by virtual screening against anti-inflammatory targets including phospholipase A2 (PLA-2), cyclooxygenase-2 (COX-2), tumor necrosis factor alpha (TNF-α), interleukin-1β (IL-1β), & NF-κB.

2. 2

   Type II diabetes mellitus

   Plant part used: Fruit.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to Aggul AG (2022)

     Excerpt berries, which is a well-known medicinal plant due to its rich phenolic content & beneficial effects on health, against STZ-induced oxidative stress in the diabetic rats. The goal of the present study was to assess the protective effects of the ethanol extract of Myrtus communis L.

   • According to Tas S (2018)

     Excerpt These findings suggest that MC fruit hydroalcoholic extract has hypoglycemic, hypolipidemic & oxidative stress inhibitory activities in STZ-induced diabetic rats. fruits hydroalcoholic extract also pointed toward the assessment of its role in oxidative-antioxidative systems in Streptozotocin-induced (STZ) diabetic rats.

   • According to Jabri MA (2018)

     Excerpt Myrtus communis L., known as common myrtle, is native to Southern Europe, North Africa, & Western Asia. In order to emphasize the importance of MC berries seeds, this review has been established by discussing its botanical, morphological, phytochemical, ethnomedicinal studies as well as its effect on digestive tract diseases.

   • According to Ertik O (2024)

     Excerpt The present study aimed to examine the protective effects of an extract prepared from Myrtus communis leaves on kidney and small intestine tissues against experimentally created postmenopausal diabetes. Methods: For this purpose, experimental rats were randomly divided into six groups (Control; ovariectomy: OVX, diabetic, ovariectomy + diabetic + D, ovariectomy + diabetic + oestrogen + D+E2, ovariectomy + diabetic + MC: OVX + D+MC) & kidney and small intestine tissues were taken after the experimental procedure.

   • According to Elfellah M (1984)

     Excerpt Elfellah M et al, Anti-hyperglycaemic effect of an extract of Myrtus communis in streptozotocin-induced diabetes in mice.

3. 3

   Osteoarthritis, arthritis, rheumatism, oedema

   Plant part used: Aerial parts.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to Sisay M (2017)

     Excerpt Ethnobotanical information revealed that MC has been a folkloric repute for the treatment of several diseases like gastric ulcer, diarrhea, dysentery, cancer, rheumatism, hemorrhage, deep sinuses, leucorrhoea, hemorrhoid, inflammation, dyspepsia, anxiety, insomnia, diabetes, hypertension, pulmonary disorders, & skin diseases. Moreover, ethnopharmacological studies revealed that the plant is endowed with extensive pharmacological activities, including antimicrobial, antidiarrheal, antidiabetic, antispasmodic, vasodilator, antiulcer, antioxidant, anticancer, anxiolytic, sedative-hypnotic, & anti-inflammatory activities, among others.

   • According to Aslan D (2024)

     Excerpt Myrtus communis (MC) groups started to receive MC (100 mg/kg, oral) either four days before (R + preMC) or immediately after (R + MC) irradiation for four days. Conclusion MC has a potential neuroprotective effect on brain tissue, attributed to its antioxidative, anti-inflammatory, & anti-lipid peroxidative properties.

   • According to Kabatas GS (2024)

     Excerpt Our data indicate further investigation of MC extract as a therapeutic adjuvant for HFD-induced pancreatic injury, acting via anti-inflammatory & antioxidant mechanisms, is worth carrying out. We investigated the effects of an ethanolic extract of Myrtus communis subsp.

   • According to Belhacene S (n.d.)

     Excerpt MMEx showed a good anti-inflammatory effect in vivo by limiting the development of carrageenan-induced paw edema. In this study, we aimed to systematically unravel the chemical profile & antioxidant & anti-inflammatory activities of myrtle methanolic extract (MMEx) using in vitro, in vivo, & in silico approaches.

   • According to Nassar M (2010)

     Excerpt The tested materials (volatile oil, alcoholic & aqueous extracts, myricetin 3-O-β-glucopyranoside, myricetin 3-O-∝-rhamnopyranoside & gallic acid) showed significant antihyperglycemic, anti-inflammatory & antinociceptive effects as compared with control groups & reference drugs. Myrtus species are characterized by the presence of phenolic acids, flavonoids, tannins, volatile oils & fatty acids.

Further indications (including other extraction modes where applicable), dosages, precautions for use, and the <strong>full scientific references</strong> (complete records, not only the short excerpts above) are available in the complete monographic record in the Lapo v2 application.