Newbouldia laevis (Lizôp-péyi) : medicinal properties in alcoholic extraction

Newbouldia laevis (Lizôp-péyi, Local hyssop, Hysope du pays) — family Bignoniacées.

This database documents alcoholic (ethanol) extractions of active substances. Our monograph currently lists 14 indications in alcoholic extraction for this species. The Lapo v2 catalogue records 32 scientific references for this species (full detail in the application).

Important — scientific references on this public page: only a short excerpt of each cited source is shown (selected abstract sentences), kept in the original language of the publication (most often English), without translation. These excerpts are not the full article text and are not a complete bibliography. The full reference records and complete monographic detail are available in the Lapo v2 application (free 30-day trial).

1. 1

   Type II diabetes mellitus

   Plant part used: Flower.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to Tanko Y (2008)

     Excerpt This study was undertaken to evaluate the hypoglycemic effect of ethanolic flower extract of Newbouldia laevis on blood glucose levels of streptozocin-induced diabetes rats. The ethanolic flower extract of N laevis possess anti-diabetic effect in streptozocin induced in diabetic rats.

   • According to Owolabi OJ (2011)

     Excerpt To investigate anti-diabetic effect of the ethanol leaf extract of Newbouldia laevis (P. The first group was untreated, the next three groups received, each day, 100, 200 and 400 mg/kg body weight of the ethanol extract N laevis and the fifth group received a reference standard, Glibenclamide (5 mg/kg).

   • According to Kolawole OT (2013)

     Excerpt The results of this study suggest that the ethanolic leaf extract of N laevis has low toxicity profile regarding haematological, blood biochemical & histological parameters. Newbouldia laevis (P.

   • According to Anaduaka EG (2014)

     Excerpt This study evaluated the effects of extracts from Newbouldia laevis leaves & stem on liver marker enzymes & antioxidant enzymes in rat model. The ethanol extracts of NL leaves & stem possessed antioxidant activity as shown by increased activities of superoxide dismutase & catalase, & glutathione levels of the diabetic rats after treatment.

   • According to Akerele JO (2011)

     Excerpt Conclusion: The study has established that the stem bark of Newbouldia laevis has antibacterial activities against bacterial isolates from infected wounds & eyes as claimed in ethnomedicinal practice. To examine the phytochemical constituents and verify the ethnomedical claim of Newbouldia laevis in treating septic wounds and eye problems.

2. 2

   Hepatitis, fatty liver, cirrhosis

   Plant part used: Sheet.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to Ebong OO (2018)

     Excerpt This study investigated the efficacy of Newbouldia laevis & Commelina benghalensis as female pro-fertility plants. The heart, liver, kidneys, ovaries, fallopian tubes & the uterus were harvested and examined for defects.

   • According to Hassan SW (2010)

     Excerpt Hepatoprotective effect & antioxidant properties of leaf extracts of Newbouldia laevis (NL) were investigated against carbon tetrachloride (CCl4)-induced acute hepatic injury in rats. The study suggests that CCl4-induced damage in rats can be ameliorated by treatment with the leaf extracts of Newbouldia laevis.

   • According to Murtala AA (2024)

     Excerpt To investigate the safety profile of subchronic oral administration of Hydroethanol leaf extract of Newbouldia laevis (NL) in rats. However, it could cause anemia at lower doses, infertility (both sexes), liver & kidney injuries at high doses.

   • According to Kolawole OT (2013)

     Excerpt The results of this study suggest that the ethanolic leaf extract of N laevis has low toxicity profile regarding haematological, blood biochemical & histological parameters. Newbouldia laevis (P.

   • According to Anaduaka EG (2014)

     Excerpt This study evaluated the effects of extracts from Newbouldia laevis leaves & stem on liver marker enzymes & antioxidant enzymes in rat model. The results confirmed that the untreated diabetic rats were subjected to oxidative stress as indicated by significantly abnormal activities of their scavenging enzymes (low superoxide dismutase, catalase & glutathione activities) to the extent of liver enzymes leakage from the hepatocytes when compared with apparently healthy rats.

3. 3

   Osteoarthritis, rheumatoid arthritis, rheumatism

   Plant part used: Stem bark.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to Woode E (2008)

     Excerpt laevis (10 - 100 mg kg-1) exhibited antiarthritic activity by inhibiting the polyarthritic phase edema by 25.30 ± 2.53 - 28.11 ± 2.02 % with no significant inhibition of the acute phase response of the rat adjuvant-induced arthritis. laevis stem bark extracts in African traditional medicine for the management of inflammatory conditions such as arthritis.

   • According to Boakye-Gyasi E (2013)

     Excerpt This study was therefore aimed at evaluating the scientific basis for the traditional use of N laevis leaves as an anti-inflammatory agent & analgesic using animal models. Various parts of Newbouldia laevis (Bignoniaceae) including the leaves have been used to relieve stomach pains, pelvic pain, Haemorrhoids & rheumatic swellings in Ghanaian & West African folk medicine with little or no scientific evidence.

   • According to Usman H (2008)

     Excerpt Analgesic & anti-inflammatory effects of the ethanolic flower extract of Newbouldia laevis were studied in rodents. The results showed that the ethanol extract possessed significant (p< 0.001) anti-nociceptive activity between 50 & 200 mg kg-1 intraperitoneally (i.p.) in mice & also dose dependent anti-inflammatory activity between 50 & 200 mg kg-1 (i.p.) in rats.

   • According to Umeyor C (2016)

     Excerpt Beauv.) is a tropical rainforest plant used in traditional folk medicine for the treatment of malaria, cough, joint pains, stomach ache, oedema & inflammation. laevis-loaded solid lipid microdispersions also produced good analgesic/anti-nociceptive property comparable with the standard diclofenac potassium.

   • According to Kolawole OT (2013)

     Excerpt The results of this study suggest that the ethanolic leaf extract of N laevis has low toxicity profile regarding haematological, blood biochemical & histological parameters. Newbouldia laevis (P.

Further indications (including other extraction modes where applicable), dosages, precautions for use, and the <strong>full scientific references</strong> (complete records, not only the short excerpts above) are available in the complete monographic record in the Lapo v2 application.