Newbouldia laevis (Lizôp-péyi) : vertus médicinales en extraction alcoolique

Newbouldia laevis (Lizôp-péyi, Hysope du pays, Local hyssop) — famille Bignoniacées.

Cette base documente les extractions alcooliques (éthanol) des substances actives. Notre monographie recense actuellement 14 indications en extraction alcoolique pour cette espèce. Le catalogue Lapo v2 enregistre 32 références scientifiques pour cette espèce (détail intégral dans l’application).

Important — références scientifiques sur cette page publique : seuls de courts extraits de chaque source citée sont présentés (phrases d’abstract sélectionnées), conservés dans leur langue d’origine (le plus souvent l’anglais), sans traduction. Ces extraits ne constituent pas le texte intégral de l’article ni une bibliographie complète. Les fiches de référence complètes et le détail monographique sont disponibles dans l’application Lapo v2 (essai gratuit 30 jours).

1. 1

   Diabète mellitus de type II

   Partie usitée : Fleur. Profil pharmacologique documenté : Glibenclamide-like.

   Références scientifiques (courts extraits)

   Courts extraits uniquement (pas le texte intégral de l’article). Fiches de référence complètes dans l’application Lapo v2.

   • Selon Tanko Y (2008)

     Extrait This study was undertaken to evaluate the hypoglycemic effect of ethanolic flower extract of Newbouldia laevis on blood glucose levels of streptozocin-induced diabetes rats. The ethanolic flower extract of N laevis possess anti-diabetic effect in streptozocin induced in diabetic rats.

   • Selon Owolabi OJ (2011)

     Extrait To investigate anti-diabetic effect of the ethanol leaf extract of Newbouldia laevis (P. The first group was untreated, the next three groups received, each day, 100, 200 and 400 mg/kg body weight of the ethanol extract N laevis and the fifth group received a reference standard, Glibenclamide (5 mg/kg).

   • Selon Kolawole OT (2013)

     Extrait The results of this study suggest that the ethanolic leaf extract of N laevis has low toxicity profile regarding haematological, blood biochemical & histological parameters. Newbouldia laevis (P.

   • Selon Anaduaka EG (2014)

     Extrait This study evaluated the effects of extracts from Newbouldia laevis leaves & stem on liver marker enzymes & antioxidant enzymes in rat model. The ethanol extracts of NL leaves & stem possessed antioxidant activity as shown by increased activities of superoxide dismutase & catalase, & glutathione levels of the diabetic rats after treatment.

   • Selon Akerele JO (2011)

     Extrait Conclusion: The study has established that the stem bark of Newbouldia laevis has antibacterial activities against bacterial isolates from infected wounds & eyes as claimed in ethnomedicinal practice. To examine the phytochemical constituents and verify the ethnomedical claim of Newbouldia laevis in treating septic wounds and eye problems.

2. 2

   Hépatite, stéatose hépatique, cirrhose

   Partie usitée : Feuille.

   Références scientifiques (courts extraits)

   Courts extraits uniquement (pas le texte intégral de l’article). Fiches de référence complètes dans l’application Lapo v2.

   • Selon Ebong OO (2018)

     Extrait This study investigated the efficacy of Newbouldia laevis & Commelina benghalensis as female pro-fertility plants. The heart, liver, kidneys, ovaries, fallopian tubes & the uterus were harvested and examined for defects.

   • Selon Hassan SW (2010)

     Extrait Hepatoprotective effect & antioxidant properties of leaf extracts of Newbouldia laevis (NL) were investigated against carbon tetrachloride (CCl4)-induced acute hepatic injury in rats. The study suggests that CCl4-induced damage in rats can be ameliorated by treatment with the leaf extracts of Newbouldia laevis.

   • Selon Murtala AA (2024)

     Extrait To investigate the safety profile of subchronic oral administration of Hydroethanol leaf extract of Newbouldia laevis (NL) in rats. However, it could cause anemia at lower doses, infertility (both sexes), liver & kidney injuries at high doses.

   • Selon Kolawole OT (2013)

     Extrait The results of this study suggest that the ethanolic leaf extract of N laevis has low toxicity profile regarding haematological, blood biochemical & histological parameters. Newbouldia laevis (P.

   • Selon Anaduaka EG (2014)

     Extrait This study evaluated the effects of extracts from Newbouldia laevis leaves & stem on liver marker enzymes & antioxidant enzymes in rat model. The results confirmed that the untreated diabetic rats were subjected to oxidative stress as indicated by significantly abnormal activities of their scavenging enzymes (low superoxide dismutase, catalase & glutathione activities) to the extent of liver enzymes leakage from the hepatocytes when compared with apparently healthy rats.

3. 3

   Arthrose, arthrite rhumatoide, rhumatisme

   Partie usitée : Écorce de Tige. Profil pharmacologique documenté : Dexaméthasone-like, Diclofenac-like.

   Références scientifiques (courts extraits)

   Courts extraits uniquement (pas le texte intégral de l’article). Fiches de référence complètes dans l’application Lapo v2.

   • Selon Woode E (2008)

     Extrait laevis (10 - 100 mg kg-1) exhibited antiarthritic activity by inhibiting the polyarthritic phase edema by 25.30 ± 2.53 - 28.11 ± 2.02 % with no significant inhibition of the acute phase response of the rat adjuvant-induced arthritis. laevis stem bark extracts in African traditional medicine for the management of inflammatory conditions such as arthritis.

   • Selon Boakye-Gyasi E (2013)

     Extrait This study was therefore aimed at evaluating the scientific basis for the traditional use of N laevis leaves as an anti-inflammatory agent & analgesic using animal models. Various parts of Newbouldia laevis (Bignoniaceae) including the leaves have been used to relieve stomach pains, pelvic pain, Haemorrhoids & rheumatic swellings in Ghanaian & West African folk medicine with little or no scientific evidence.

   • Selon Usman H (2008)

     Extrait Analgesic & anti-inflammatory effects of the ethanolic flower extract of Newbouldia laevis were studied in rodents. The results showed that the ethanol extract possessed significant (p< 0.001) anti-nociceptive activity between 50 & 200 mg kg-1 intraperitoneally (i.p.) in mice & also dose dependent anti-inflammatory activity between 50 & 200 mg kg-1 (i.p.) in rats.

   • Selon Umeyor C (2016)

     Extrait Beauv.) is a tropical rainforest plant used in traditional folk medicine for the treatment of malaria, cough, joint pains, stomach ache, oedema & inflammation. laevis-loaded solid lipid microdispersions also produced good analgesic/anti-nociceptive property comparable with the standard diclofenac potassium.

   • Selon Kolawole OT (2013)

     Extrait The results of this study suggest that the ethanolic leaf extract of N laevis has low toxicity profile regarding haematological, blood biochemical & histological parameters. Newbouldia laevis (P.

D’autres indications (y compris d’autres modes d’extraction le cas échéant), posologies, précautions d’emploi et les <strong>références scientifiques complètes</strong> (fiches intégrales, pas seulement les courts extraits ci-dessus) sont disponibles dans la fiche monographique de l’application Lapo v2.