Ocimum micranthum (Ti-fonbazen) : medicinal properties in alcoholic extraction

Ocimum micranthum (Ti-fonbazen, Little Framboisin, Petit Framboisin) — family Lamiacées.

Scientific synonyms : Ocimum americanum-L, O canum-Sims, O frutescens Siebold, O micranthum Willd..

Recognised external sources linked to this monograph: TRAMIL.

This database documents alcoholic (ethanol) extractions of active substances. Our monograph currently lists 8 indications in alcoholic extraction for this species. The Lapo v2 catalogue records 43 scientific references for this species (full detail in the application).

Important — scientific references on this public page: only a short excerpt of each cited source is shown (selected abstract sentences), kept in the original language of the publication (most often English), without translation. These excerpts are not the full article text and are not a complete bibliography. The full reference records and complete monographic detail are available in the Lapo v2 application (free 30-day trial).

1. 1

   Cancer: adjuvant treatment for basal cell adenocarcinoma

   Plant part used: Aerial parts.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to Anu-Smitha K.M (2021)

     Excerpt The genus Ocimum belonging to the family Lamiaceae, have been widely used in traditional medicines for the management of inflammation, dysentery, & chronic diarrhea as well as insect bites. The study identified the antioxidant, anti-inflammatory, anti-genotoxic & anticancer properties of ultrasound-assisted extracted Ocimumplants, with higher activity in OB & OG species.

   • According to Salles Trevisan M.T (2006)

     Excerpt The data generated with Ocimum species indicates that essential oils obtained from various herbs and spices may have an important role to play in cancer chemoprevention, functional foods, & in the preservation of pharmacologic products. purpurascens, Ocimum basilicum, Ocimum gratissimum, Ocimum micranthum, & Ocimum tenuiflorum, were evaluated using a high-performance liquid chromatography-based hypoxanthine/xanthine oxidase & the DPPH assays.

   • According to Ricarte L (2020)

     Excerpt The in vitro cytotoxic activities of the essential oils have been evaluated on breast adenocarcinoma (MCF-7), lung carcinoma (NCI-H292), pro-myelocytic leukemia (HL-60), & cervical adenocarcinoma (HEP-2) human cell lines, & pro-myelocytic leukemia cells lines (HL-60) were found to be the most sensitive to all the EO tested than the others. The essential oils obtained by hydrodistillation from fresh leaves of Vitex agnus-castus & Ocimum campechianum, & from fresh inflorescences of Ocimum carnosum were analysed by GC-FID and GC-MS.

   • According to Caamal-Herrera IO (2018)

     Excerpt The aqueous extract showed a significant (p < 0.05) antiproliferative effect on hFB cells at a concentration of 4%, with cell proliferation percentage values of 73.56% & 20.59% by MTT method & Trypan Blue assay, respectively; the same effect was observed for the ethanolic extract at concentration from 0.06% to 0.25% using MTT method & at a concentration from 0.125% to 0.25% using Trypan Blue assay. Conclusion: These assays showed that low concentrations of essential oil & extracts of OM leaves are sufficient to cause an antiproliferative effect on the hFB cell line but do not produce an antimicrobial effect against the microorganisms evaluated.

   • According to Guardado-Yordi E (2022)

     Excerpt It is suggested to promote studies on multiple herbal remedies, & the antiproliferative & cytotoxic activities of the compounds, as well as new strategies that relate phytochemistry with bioactivity, toxicological evaluations on acute & long-term toxicity, mechanisms of action, pharmacodynamic, & pharmacokinetic studies. There is extensive ethnobotanical information on Ocimum campechianum as it is widely used by the natives of Central & South America & the Amazon.

2. 2

   Bacterial infection: Staphylococcus aureus, Bacillus subtilis and Pseudomonas aeruginosa

   Plant part used: Sheet.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to Hendra Dian (2022)

     Excerpt There have been many studies reporting the potential antibacterial activity of the Ocimum plant. The five species are known to contain many chemical constituents & have good antibacterial activity against several pathogenic bacteria.

   • According to Parida R (2014)

     Excerpt The essential oil composition, In vitro antioxidant & antimicrobial activity of the EO of OA were evaluated in this research to explore its potential for future use. Conclusion: Both the antimicrobial & anti-oxidant activity of OA showed its potential for further use as natural antioxidant & preservative.

   • According to Blessy-Jacob BP (2022)

     Excerpt This shampoo proved to give antibacterial property against Staphylococcus aureus. Accordingly in present work, we tracked down great properties for polyherbal shampoo.The main ingredients used in the formulation are Ocimum americanum oil, aloe vera gel, sodium lauryl sulphate, glycerine, gelatin, sodium chloride & bentonite.

   • According to Caamal-Herrera IO (2018)

     Excerpt Methods: The minimal inhibitory concentration (MIC) of essential oil & aqueous & ethanolic extracts of OM leaves against Staphylococcus aureus, Bacillus subtilis, Pseudomonas aeruginosa & Candida albicans was determined using the microdilution technique. In the case of S aureus, B subtilis, & P aeruginosa, the MIC of the aqueous & ethanolic extract was 125 μL/mL.

   • According to Zaidi K.U (2018)

     Excerpt Synergistic antimicrobial activity was found when methanolic extract of leaves of OS was used in combination with fluconazole against C. Aqueous extract of leaves of OS in combination with fluconazole showed partial synergistic antimicrobial activity against catheter tip (CT) & high vaginal swab (HVS) & urine (U) (FIC=0.5-1.0).

3. 3

   Fungal infection: Candida albicans

   Plant part used: Sheet.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to Hendra Dian (2022)

     Excerpt There have been many studies reporting the potential antibacterial activity of the Ocimum plant. The five species are known to contain many chemical constituents & have good antibacterial activity against several pathogenic bacteria.

   • According to Parida R (2014)

     Excerpt The essential oil composition, In vitro antioxidant & antimicrobial activity of the EO of OA were evaluated in this research to explore its potential for future use. Conclusion: Both the antimicrobial & anti-oxidant activity of OA showed its potential for further use as natural antioxidant & preservative.

   • According to Zaidi K.U (2018)

     Excerpt Candida albicans is the most prevalent fungal pathogen in humans. It is the causative agent & most associated with serious fungal infection, accounting for more than 90% of cases.

   • According to Caamal-Herrera IO (2018)

     Excerpt Methods: The minimal inhibitory concentration (MIC) of essential oil & aqueous & ethanolic extracts of OM leaves against Staphylococcus aureus, Bacillus subtilis, Pseudomonas aeruginosa & Candida albicans was determined using the microdilution technique. Results: Candida albicans was more susceptible to the ethanolic extract & the aqueous extract (MIC value of 5 μL/mL & 80 μL/mL respectively).

   • According to Amber K (2010)

     Excerpt Holy basil, Ocimum sanctum (L.) is time-honored for its medicinal properties; however, its antimicrobial characteristics are used only in 'Ayurvedic medicines'. To put forward this approach, antifungal activity has been assessed in seventy-four fluconazole-sensitive & sixteen fluconazole-resistant Candida isolates.

Further indications (including other extraction modes where applicable), dosages, precautions for use, and the <strong>full scientific references</strong> (complete records, not only the short excerpts above) are available in the complete monographic record in the Lapo v2 application.