Orthosiphon aristatus : medicinal properties in alcoholic extraction

Orthosiphon aristatus (Babin ’chat, Moustache-à-chat, Thé de java) — family Lamiacées.

Scientific synonyms : Clerodendranthus spicatus (Thunb.) C.Y. Wu, C spicatum Thunb, C stamineus (Benth.) Kud, Ocimum aristatum Blume, O grandiflorum Blume, Orthosiphon stamineus Benth., O spiralis (Lour.) Merr., O velteri Doan, O spicatus (Thunb.) Backer, O tagawae Murat..

Recognised external sources linked to this monograph: French Pharmacopoeia.

This database documents alcoholic (ethanol) extractions of active substances. Our monograph currently lists 13 indications in alcoholic extraction for this species. The Lapo v2 catalogue records 74 scientific references for this species (full detail in the application).

Important — scientific references on this public page: only a short excerpt of each cited source is shown (selected abstract sentences), kept in the original language of the publication (most often English), without translation. These excerpts are not the full article text and are not a complete bibliography. The full reference records and complete monographic detail are available in the Lapo v2 application (free 30-day trial).

1. 1

   Indication

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to Samidurai D (2020)

     Excerpt Orthosiphon aristatus is a traditional folk medicine extensively used in Southeast Asia because of its various pharmacological effects, including antioxidant, antitumor, & hypoglycemic activities. Orthosiphon extracts have been found to be cytotoxic to hepatocellular carcinoma (HCC) cells, which is attributed to their phytochemical content.

   • According to AL-Shehade SA (2023)

     Excerpt Orthosiphon aristatus (Blume) Miq, a traditional plant in South Asia, has previously been shown to attenuate obesity and hyperglycaemic conditions. Liver enzymes including alanine aminotransferase & aspartate transaminase were significantly reduced in treated mice by 74.2% ± 7.69 & 52.8% ± 7.83, respectively.

   • According to Han CJ (2008)

     Excerpt Han CJ et al, Effect of methanol leaf extract of Orthosiphon stamineus Benth on hepatic drug metabolizing enzymes in Sprague Dawley (SD) rats, J of Biosci, 19(1) :21–3, 2008.

   • According to Alshawsh, M.A (2011)

     Excerpt Alshawsh, M.A et al, Hepatoprotective effects of Orthosiphon stamineus extract on thioacetamide-induced liver cirrhosis in rats.

   • According to Yam MF (2007)

     Excerpt Yam MF et al, Antioxidant & hepatoprotective effects of Orthosiphon stamineus Benth.

2. 2

   Indication

   Plant part used: Parties aériennes. Mentioned synergistic association: Andrographis paniculata.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to Mohamed EA (2015)

     Excerpt In streptozotocin-induced diabetic rats, only the group treated with 1000 mg/kg of the extract showed significantly (P < 0.05) lower plasma glucose levels after starch loading. stamineus can be considered as a potential agent for the management of diabetes mellitus.

   • According to PAN Y (2011)

     Excerpt Andrographis paniculata (AP), Centella asiatica (CA) & Orthosiphon stamineus (OS) are three popular herbs traditionally used worldwide. AP is known for the treatment of infections & diabetes & CA is good for wound healing & healthy skin while OS is usually consumed as tea to treat kidney & urinary disorders.

   • According to Sriplang K (2007)

     Excerpt Sriplang K et al, Effects of Orthosiphon stamineus aqueous extract on plasma glucose concentration & lipid profile in normal & streptozotocin-induced diabetic rats, J of Ethnopharm, 109(3) :510–4, 2007.

   • According to HARTANI D (2022)

     Excerpt This study evaluated the selected pharmacognostic characters, antioxidant activities, total phenolic content, & the hepatic safety of a polyherbal formulation containing seven plant constituents used by Klinik Wisata Kesehatan Jamu Kalibakung, Tegal, Indonesia, to treat diabetes patients. This study set the pharmacognostic standards for an antidiabetic polyherbal formulation with excellent antioxidant activities, in which its traditional use as a decoction was safe for the hepatic cells.

   • According to Pan Y (2011)

     Excerpt orthosiphon stamineus (OS) has been traditionally used to treat diabetes, kidney & urinary disorders, high blood pressure & bone or muscular pain.

3. 3

   Indication

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to Mohamed EA (2015)

     Excerpt In streptozotocin-induced diabetic rats, only the group treated with 1000 mg/kg of the extract showed significantly (P < 0.05) lower plasma glucose levels after starch loading. stamineus can be considered as a potential agent for the management of diabetes mellitus.

   • According to Sriplang K (2007)

     Excerpt Sriplang K et al, Effects of Orthosiphon stamineus aqueous extract on plasma glucose concentration & lipid profile in normal & streptozotocin-induced diabetic rats, J of Ethnopharm, 109(3) :510–4, 2007.

   • According to HARTANI D (2022)

     Excerpt This study evaluated the selected pharmacognostic characters, antioxidant activities, total phenolic content, & the hepatic safety of a polyherbal formulation containing seven plant constituents used by Klinik Wisata Kesehatan Jamu Kalibakung, Tegal, Indonesia, to treat diabetes patients. This study set the pharmacognostic standards for an antidiabetic polyherbal formulation with excellent antioxidant activities, in which its traditional use as a decoction was safe for the hepatic cells.

   • According to Pan Y (2011)

     Excerpt orthosiphon stamineus (OS) has been traditionally used to treat diabetes, kidney & urinary disorders, high blood pressure & bone or muscular pain.

   • According to PAN Y (2011)

     Excerpt AP is known for the treatment of infections & diabetes & CA is good for wound healing & healthy skin while OS is usually consumed as tea to treat kidney & urinary disorders. Andrographis paniculata (AP), Centella asiatica (CA) & Orthosiphon stamineus (OS) are three popular herbs traditionally used worldwide.

Further indications (including other extraction modes where applicable), dosages, precautions for use, and the <strong>full scientific references</strong> (complete records, not only the short excerpts above) are available in the complete monographic record in the Lapo v2 application.