Piper auritum (Malenmbé) : medicinal properties in alcoholic extraction

Piper auritum (Malenmbé, Latjérat, Rat-tailed, Queue-à-rat) — family Pipéracées.

Scientific synonyms : Artante aurita-(K)-M, Piper alstonii-T, P aurutilaminium-T, P heraldi-T, P perfongipes-T, Schilleria aurita-(K)-K.

Recognised external sources linked to this monograph: TRAMIL.

This database documents alcoholic (ethanol) extractions of active substances. Our monograph currently lists 4 indications in alcoholic extraction for this species. The Lapo v2 catalogue records 24 scientific references for this species (full detail in the application).

Important — scientific references on this public page: only a short excerpt of each cited source is shown (selected abstract sentences), kept in the original language of the publication (most often English), without translation. These excerpts are not the full article text and are not a complete bibliography. The full reference records and complete monographic detail are available in the Lapo v2 application (free 30-day trial).

1. 1

   Fungal infection: Fusarium oxysporum f. sp. Vanillae

   Plant part used: Pest control and veterinary products.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to del Socorro Fernandes M (2021)

     Excerpt The effect of chitosan addition on the production of secondary metabolites of Piper auritum ethanolic extracts was tested, as well as the in vitro fungicidal activity against Fusarium oxysporum f. vanillae was lower with chitosan treatment (1.5 mg mL-1) compared to control (5.1 mg mL-1).

   • According to Chacon C (2021)

     Excerpt Chacon C et al, In Vitro Antifungal Activity & Chemical Composition of Piper auritum Kunth Essential Oil against Fusarium oxysporum & Fusarium equiseti, Agronomy, 11(6):1098, 2021-Abtract: The essential oils of plants of the genus Piper have secondary metabolites that have antimicrobial activity related to their chemical composition. The objective of our work was to determine the chemical composition & evaluate the antifungal activity of the aerial part essential oil of PA obtained by hydrodistillation on Fusarium oxysporum & Fusarium equiseti isolated from Capsicum chinense.

   • According to Valdès-Perez O (2016)

     Excerpt Evaluate the antifungal activity of Piper auritum & Cymbopogon citratus essential oils against four fungal strains isolated from indoor air of repositories of the National Archives of Cuba. RESULTS: Both essential oils showed positive antifungal activity against all strains at the concentration of 50%, except in A flavus in the first case & A niger for the last.

   • According to Trujillo-Santiago E (2021)

     Excerpt The antioxidant & antimicrobial effects of Hierba Santa (Piper auritum Kunth) ethanolic extracts (HSEE) from plant powder of particle sizes 425 μm (EPA) & 850 μm (EPB) were evaluated in raw & raw-cooked beef burgers stored for 9 days at 4 °C, as well as raw-frozen & raw-frozen-cooked beef burgers stored for 90 days at –20 °C. Four treatments were prepared, including control (without extract), solution of sodium ascorbate (NaASC at 500 mg/Kg), MEPA (meat with HSEE from EPA at 750 mg/kg) & MEPB (meat with HSEE from EPB at 750 mg/kg).

2. 2

   Bacterial infection: Escherichia coli serotype O2

   Plant part used: Pest control and veterinary products.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to del Socorro Fernandes M (2021)

     Excerpt The effect of chitosan addition on the production of secondary metabolites of Piper auritum ethanolic extracts was tested, as well as the in vitro fungicidal activity against Fusarium oxysporum f. The concentrations of flavonoids, phenols, terpenes, alkaloids & salicylic acid were measured in PA ethanolic extracts & the antifungal activity was measured with the median effective concentration (EC50).

   • According to Aguilar-Urquizo E (2020)

     Excerpt The objective of this study was to evaluate the phytobiotic activity, in vitro & in vivo, of an extract & an essential oil of Piper auritum & Ocimum basilicum on avian Escherichia coli serotype O2 in broiler chickens experimentally infected. A concentration of 1×108 CFU mL-1 of bacteria was seeded & on each sense disc, 25 µL of the extract or essential oil were poured, except on the positive or negative control.

   • According to Trujillo-Santiago E (2021)

     Excerpt The antioxidant & antimicrobial effects of Hierba Santa (Piper auritum Kunth) ethanolic extracts (HSEE) from plant powder of particle sizes 425 μm (EPA) & 850 μm (EPB) were evaluated in raw & raw-cooked beef burgers stored for 9 days at 4 °C, as well as raw-frozen & raw-frozen-cooked beef burgers stored for 90 days at –20 °C. Four treatments were prepared, including control (without extract), solution of sodium ascorbate (NaASC at 500 mg/Kg), MEPA (meat with HSEE from EPA at 750 mg/kg) & MEPB (meat with HSEE from EPB at 750 mg/kg).

   • According to Chacon C (2021)

     Excerpt Chacon C et al, In Vitro Antifungal Activity & Chemical Composition of Piper auritum Kunth Essential Oil against Fusarium oxysporum & Fusarium equiseti, Agronomy, 11(6):1098, 2021-Abtract: The essential oils of plants of the genus Piper have secondary metabolites that have antimicrobial activity related to their chemical composition. The objective of our work was to determine the chemical composition & evaluate the antifungal activity of the aerial part essential oil of PA obtained by hydrodistillation on Fusarium oxysporum & Fusarium equiseti isolated from Capsicum chinense.

   • According to Valdès-Perez O (2016)

     Excerpt Evaluate the antifungal activity of Piper auritum & Cymbopogon citratus essential oils against four fungal strains isolated from indoor air of repositories of the National Archives of Cuba. RESULTS: Both essential oils showed positive antifungal activity against all strains at the concentration of 50%, except in A flavus in the first case & A niger for the last.

3. 3

   Oxidative stress

   Plant part used: Sheet.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to Gutiérrez RMP (2016)

     Excerpt Bioactivity-guided fractionation of methanol extracts from leaves of Piper auritum produced four triterpenoid saponin compounds 1-4. The effects of lipid peroxidation & oxidative stress in the liver, pancreas, & kidney were reversed, with reductions insulin resistance & stimulation of insulin production.

   • According to Neira Gonzalez Am (2014)

     Excerpt To investigate the effect of hypoglycaemic, hypolipidemic, oxidative stress, insulin resistance & advanced glycation end products (AGEs) formation of hexane extract from Piper auritum. Conclusion: The hexane extract from PA leaves can efficiently inhibit insulin resistance, AGEs formation, improvement of renal function, lipid abnormalities & oxidative stress, indicating that its therapeutic properties may be due to the interaction of hexane extract components with multiple targets involved in diabetes pathogenesis,.

   • According to Pérez Gutiérrez RM (2012)

     Excerpt Pérez Gutiérrez RM et al, Effect of the hexane extract of Piper auritum on insulin release from -cell & oxidative stress in streptozotocin-induced diabetic rat.

   • According to Pérez Gutierrez RM (2016)

     Excerpt Bioactivity-guided fractionation of methanol extracts from leaves of Piper auritum produced four triterpenoid saponin compounds 1-4. The effects of lipid peroxidation & oxidative stress in the liver, pancreas, & kidney were reversed, with reductions insulin resistance & stimulation of insulin production.

   • According to Conde-Hernandez LA (2014)

     Excerpt Extracts from fresh & dried samples of Mexican pepper leaf (Piper auritum Kunth) & "papalo" (Porophyllum ruderale) were obtained using a stirring or an ultrasound extraction system with five types of solvents (water, 50:50% v/v ethanol: water, 70:30% v/v ethanol: water, 85:15% v/v ethanol:1.5N HCl, & ethanol). Total phenolic compounds & antioxidant activity were evaluated with the phenol Folin Ciocalteu reagent & the ABTS method, respectively.

Further indications (including other extraction modes where applicable), dosages, precautions for use, and the <strong>full scientific references</strong> (complete records, not only the short excerpts above) are available in the complete monographic record in the Lapo v2 application.