Pogostemon cablin (Patjouli) : medicinal properties in alcoholic extraction

Pogostemon cablin (Patjouli, Patchouli, Patchouly) — family Lamiacées.

Scientific synonyms : Mentha auricularia-Blanco, Pogostemon battakianus-Ridl., P comosus-Miq., P javanicus-Backer ex Adelb., P mollis-Hassk, P patchouly-Pellet.

This database documents alcoholic (ethanol) extractions of active substances. Our monograph currently lists 8 indications in alcoholic extraction for this species. The Lapo v2 catalogue records 70 scientific references for this species (full detail in the application).

Important — scientific references on this public page: only a short excerpt of each cited source is shown (selected abstract sentences), kept in the original language of the publication (most often English), without translation. These excerpts are not the full article text and are not a complete bibliography. The full reference records and complete monographic detail are available in the Lapo v2 application (free 30-day trial).

1. 1

   Pulmonary inflammation, acute lung injury, pulmonary oedema

   Plant part used: Aerial parts.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to Su Zuqing (2015)

     Excerpt Patchouli alcohol (PA) is a tricyclic sesquiterpene isolated from Pogostemon cablin, which exerts anti-inflammatory, anti-influenza & cognitive-enhancing bioactivities. The results of the present study demonstrated that pretreatment with PA significantly increased survival rate, attenuated histopathologic damage & lung edema, & decreased the protein content in the bronchoalveolar lavage fluid (BALF) of mice with ALI.

   • According to Pandey SK (2022)

     Excerpt The purpose of this study was to examine & compare the chemical composition, antimicrobial activity, & various biological activities of Pogostemon cablin flower & leaf essential oils. Highest anti-inflammatory activity was exhibited by PCLEO (IC50 = 4.49 µg/mL).

   • According to Lu TS (2011)

     Excerpt Lu TS et al, Analgesic & Anti-Inflammatory Activities of the Methanol Extract from Pogostemon cablin, eCAM, 2011-doi:10.1093/ecam/nep183,.

   • According to Yoon SC (2016)

     Excerpt Yoon SC et al, Anti-allergic & anti-inflammatory effects of aqueous extract of Pogostemon cablin, Inter J of Molecular Med, 3(1): 217–24, 2016,.

   • According to LI CW (2013)

     Excerpt the aim of this study was to investigate the anti-inflammatory property of the ethanol extract of the root & rhizome of Pogostemon cablin (ERP). The anti-inflammatory effect was evaluated using four animal models including xylene-induced mouse ear edema, acetic acid-induced mouse vascular permeability, carrageenan-induced mouse pleurisy, & carrageenan-induced mouse hind paw edema.

2. 2

   Bacterial infection: Methicillin-resistant Staphylococcus aureus, Methicillin-sensitive S. aureus, Streptococcus pyogenes

   Plant part used: Sheet.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to Dechayont B (2017)

     Excerpt The ethanolic extract had the greatest activity against methicillin resistant Staphylococcus aureus , methicillin sensitive S. aureus , & Streptococcus pyogenes with zone diameters of 11.67±1.53 , 10.33±2.52 , & 10.33±1.15 mm, respectively.

   • According to Pandey SK (2022)

     Excerpt The purpose of this study was to examine & compare the chemical composition, antimicrobial activity, & various biological activities of Pogostemon cablin flower & leaf essential oils. Apart from their antimicrobial activity, the PCLEO was found to outperform both PCFEO as well as the standards in their respective assays.

   • According to Pullagummi, C (2014)

     Excerpt Pullagummi, C et al, Comparative studies on antibacterial activity of Patchouli [Pogostemon cablin (Blanco) Benth] & Geranium (Pelargonium graveolens) aromatic medicinal plants, Afri J of Biotechnol, 2014; 13(23): 2379-84-DOI: 10.5897/AJB12.1369,.

   • According to Krithika S (2022)

     Excerpt Leaf Ethyl acetate extract showed significantly better antimicrobial activity against both Staphylococcus aureus 6538 (Gram-positive) (SA) & Klebsiella pneumonia ATCC 27,736 (Gram-negative) bacteria compared to the Hexane extract & was subjected to phytochemical analysis & chromatographic seperation. cablin were extracted using Hexane & ethyl acetate.

   • According to Kim K (2015)

     Excerpt Compounds 1-3 displayed weak antibacterial activity against two gram-positive bacteria, Bacillus subtilis & Staphylococcus aureus. A new octaketide, named cytosporone V (1), & two other known phenylethanoid glycosides (2-3), were isolated from the aerial parts of Pogostemon cablin (Blanco) Benth.

3. 3

   Osteoarthritis, arthritis, rheumatism, oedema

   Plant part used: Root.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to LI CW (2013)

     Excerpt the aim of this study was to investigate the anti-inflammatory property of the ethanol extract of the root & rhizome of Pogostemon cablin (ERP). The anti-inflammatory effect was evaluated using four animal models including xylene-induced mouse ear edema, acetic acid-induced mouse vascular permeability, carrageenan-induced mouse pleurisy, & carrageenan-induced mouse hind paw edema.

   • According to Su Zuqing (2015)

     Excerpt Patchouli alcohol (PA) is a tricyclic sesquiterpene isolated from Pogostemon cablin, which exerts anti-inflammatory, anti-influenza & cognitive-enhancing bioactivities. These results indicated that PA may exert potent protective effects against LPS-induced ALI in mice, the mechanisms of which are possibly associated with the anti-inflammatory & antioxidative activities of PA.

   • According to Pandey SK (2022)

     Excerpt The purpose of this study was to examine & compare the chemical composition, antimicrobial activity, & various biological activities of Pogostemon cablin flower & leaf essential oils. Highest anti-inflammatory activity was exhibited by PCLEO (IC50 = 4.49 µg/mL).

   • According to Lu TS (2011)

     Excerpt Lu TS et al, Analgesic & Anti-Inflammatory Activities of the Methanol Extract from Pogostemon cablin, eCAM, 2011-doi:10.1093/ecam/nep183,.

   • According to Yoon SC (2016)

     Excerpt Yoon SC et al, Anti-allergic & anti-inflammatory effects of aqueous extract of Pogostemon cablin, Inter J of Molecular Med, 3(1): 217–24, 2016,.

Further indications (including other extraction modes where applicable), dosages, precautions for use, and the <strong>full scientific references</strong> (complete records, not only the short excerpts above) are available in the complete monographic record in the Lapo v2 application.