Raphanus sativus (Radish) : medicinal properties in alcoholic extraction

Raphanus sativus (Radish, Radi, Radis) — family Brassicacées.

Scientific synonyms : Raphanus acanthiformis J.M. Morel ex Sasaki, R candidus-Vor, R raphanistrum var sativus-(L)-Beck, R taquéti-H Lév.

Recognised external sources linked to this monograph: French Pharmacopoeia.

This database documents alcoholic (ethanol) extractions of active substances. Our monograph currently lists 23 indications in alcoholic extraction for this species. The Lapo v2 catalogue records 125 scientific references for this species (full detail in the application).

Important — scientific references on this public page: only a short excerpt of each cited source is shown (selected abstract sentences), kept in the original language of the publication (most often English), without translation. These excerpts are not the full article text and are not a complete bibliography. The full reference records and complete monographic detail are available in the Lapo v2 application (free 30-day trial).

1. 1

   Type II diabetes mellitus (Cv: Carmen/Jutrzenka/Saxa & Warta): through inhibition of alpha-amylase and glucosidase

   Plant part used: leaf.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to Riaz M (2023)

     Excerpt The alpha amylase inhibition was also done through a standard procedure cited in the literature. All of the plant extracts ( RS) inhibited alpha amylase, but the ethyl acetate extract (36.2% inhibition) was the most potent.

   • According to VADIVELAN R (2012)

     Excerpt The goal of the present study is to evaluate the Invitro antidiabetic activity of Raphanus sativus ethanolic extract & fractions by α-glucosidase & α -amylase inhibitory activity. R sativus ethanolic extract and fractions showed dose dependent inhibition of α-glucosidase & α -amylase enzyme & exhibited lower inhibitory activity than acarbose.

   • According to SAHA S (2025)

     Excerpt These findings suggest that RS leaf extract exerts antidiabetic effects through glucose regulation, oxidative stress reduction, & apoptosis inhibition, validating its therapeutic potential against type 2 diabetes mellitus. Though the antidiabetic effects of Raphanus sativus leaf have been identified, the mechanisms underlying its antihyperglycemic activity have not been thoroughly investigated.

   • According to Elnour RO (2022)

     Excerpt Thyroid hormone increases metabolic actions in almost every tissue, & the current study was an attempt to evaluate scientifically the effects of Raphanus satives (Radish) in the treatment of diabetes mellitus.Objectives: The main objective of this study is to evaluate the hypoglycemic effect of Raphanus sativus (Radish) on induced hyperglycemic rats. The effects of Raphanus satives (Radish) in the treatment of diabetes mellitus were evaluated scientifically in this study.

   • According to Roses C (2023)

     Excerpt Red radish (Raphanus sativus.) contains several secondary plant metabolites that can exert a protective effect on human health. The aim of this work is to evaluate the effects of glucosinolate (GSL)-enriched radish with elicitors on the intestinal microbiota & metabolic syndrome-related functionalities by using an in vitro dynamic gastrointestinal system & several cellular models developed to study the GSL impact on different health indicators such as blood pressure, cholesterol metabolism, insulin resistance, adipogenesis, & reactive oxygen species (ROS).

2. 2

   Liver disorders: abnormal serum parameters: SGOT, SGPT, SLDH, SAP, total serum bilirubin

   Plant part used: leaf.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to Anwar R (2006)

     Excerpt Raphanus sativus (Radish) leaves powder, its water & ethanol extracts significantly decreased the activity of SGOT, SGPT, SLDH, SAP & serum total bilirubin in paracetamol induced rabbits. Crude powder of RS also declined the SGOT, SGPT, SLDH, SAP & serum total bilirubin levels after the chornic administration of paracetamol.

   • According to Chaturvedi P (2007)

     Excerpt Degree of lipid peroxidation caused by paracetamol was measured in terms of thiobarbituric acid reactive substances (TBARS) & protection was measured in reference to serum glutamate oxaloacetate transaminase (SGOT), serum glutamate aspartate transaminase (SGPT), & blood & hepatic levels of antioxidants like glutathione & catalase. The methanol extract of Raphanus sativus root extract showed a protective effect on paracetamol-induced hepatotoxicity in a dose-dependent manner.

   • According to SYED SN (2014)

     Excerpt Biochemical parameters (AST, ALT, Alkaline phosphatase, Total Bilirubin), histopathological examination of liver & in vivo antioxidant tests [CAT, GSH & MDA] were done. Raphanus sativus is reported to have a variety of biological activities.

   • According to Hasan M (2014)

     Excerpt The effects of RSE on the hepatic enzymes, namely alanine aminotransferase (ALT), aspartate aminotransferase (AST) & alkaline phosphatase (ALP), the levels of lipid peroxide (LPO) & liver histology were also evaluated. The dietary RSE, however, significantly ameliorated the above atherogenic lipids & liver enzymes.

   • According to Roses C (2023)

     Excerpt Red radish (Raphanus sativus.) contains several secondary plant metabolites that can exert a protective effect on human health.

3. 3

   Bacterial infection: Escherichia coli, Klebsiella pneumoniae, Proteus vulgaris, Pseudomonas aeruginosa, Staphylococcus aureus, Shigella sonnei, Salmonella typhi, Salmonella paratyphi

   Plant part used: seed.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to Ahmad F (2012)

     Excerpt Objectives: The aim of the study is to test the potentiality of different solvent extracts (Ethanol, Methanol, Ethyl Acetate, Chloroform, Benzene, Aqueous hot & Aqueous cold) against various pathogenic bacterial strains E .coli (ATCC25922), Klebsiella pneumonia (ATCC-27736), Proteus vulgaris (AT CC - 6380), Pseudomonas aeruginosa (ATCC-27853), Staphylococcus aureus (ATCC-25923), Shigella sonnei (ATCC-25931), Salmonella typhi (ATCC-25241) & Salmonella paratyphi (ATCC-9150). Results : Among all the extracts Ethanolic & Methanolic extracts showed maximum antibacterial activity against all the bacterial strain used with a zone of inhibition ranges from 1221mm & the least activity was observed in Aqueous cold extract with zone of inhibition ranges from 7-9mm.

   • According to Aerts AM (2007)

     Excerpt The antifungal activity of RsAFP2, a plant defensin from Raphanus sativus, involves the induction of reactive oxygen species in Candida albicans.

   • According to Khan KI (1985)

     Excerpt The antimicrobial activity of Allium sativum (garlic) Allium cepa (Onion) & Raphanus sativus (radish) Jl of Pharm.

   • According to Abdou A (1972)

     Excerpt Abdou A et al, Antibacterial activity of Allium sativum, Allium cepa, Raphanus sativus, Capsicum frutescens, Fruca sativa & Allium kurrat on bacteria.

   • According to SHUKLA S (2011)

     Excerpt SHUKLA S et al, ANTIMICROBIAL EFFICACY OF RAPHANUS SATIVUS ROOT JUICE Inter Jl of Pharm & Pharmaceut Sci, 3, Suppl 5, 2011,.

Further indications (including other extraction modes where applicable), dosages, precautions for use, and the <strong>full scientific references</strong> (complete records, not only the short excerpts above) are available in the complete monographic record in the Lapo v2 application.