Ravenala madasgascariensis (The Traveller’s Tree) : medicinal properties in alcoholic extraction

Ravenala madasgascariensis (The Traveller’s Tree, Arbre du voyageur) — family Strelitziaceae.

Scientific synonyms : Heliconia ravenala Willemet, Urania ravenala (Willemet) A.Rich.., Urania speciosa Willd...

Recognised external sources linked to this monograph: French Pharmacopoeia.

This database documents alcoholic (ethanol) extractions of active substances. Our monograph currently lists 6 indications in alcoholic extraction for this species. The Lapo v2 catalogue records 20 scientific references for this species (full detail in the application).

Important — scientific references on this public page: only a short excerpt of each cited source is shown (selected abstract sentences), kept in the original language of the publication (most often English), without translation. These excerpts are not the full article text and are not a complete bibliography. The full reference records and complete monographic detail are available in the Lapo v2 application (free 30-day trial).

1. 1

   Type II diabetes mellitus

   Plant part used: Sheet.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to Author (2017)

     Excerpt The objective of this work was to determine the effect of ethanolic extract of Ravenala madagascariensis on pregnant Wistar rats & their offspring. In rats, the treatment did not affect weight gain during pregnancy; normalized glycemia values & increased lipid profile; improved the response to the glucose tolerance test & maintained its effect days after administration; did not modify the water consumed, the urine excreted, the urinary biochemical parameters, nor the maternal reproductive parameters.

   • According to Priyadarshini S (2020)

     Excerpt Leaves of Ravenala madagascariensis have been traditionally used in the treatment of diabetes & was scientifically proven to be effective as an antidiabetic, hypolipidemic, renoprotective & antioxidant agent. Up to 80% of the patients with pancreatic cancer are found to be diabetic at the time of diagnosis.

   • According to Priyadarsini R (2010)

     Excerpt The ethanolic and aqueous extracts showed a significant inhibitory effect on glucose diffusion in vitro and accordingly were screened at 200 and 400mg/kg, b.w for the in vivo antidiabetic activity on alloxan induced diabetic rats. Ravenala madagascariensis Sonn., (Strelitziaceae) commonly known as Traveler’s palm has been widely used in traditional system of medicine for diabetes.

   • According to Rakotodramanana DA (2023)

     Excerpt Androsta-1,4-dien-3,16-dione was isolated for the first time from the plant kingdom of the ethanolic extract of the Ravenala madagascariensis' inflorescence by the bio-guided method. The pharmacological mechanism of its vaso-relaxing action was analysed on isolated rat aorta using free-endothelial vascular tissue, specific contracting reagents (CaCl2 & KCl), antagonist (propranolol), enzyme inhibitors (L-NAME, methylene blue) & channel blocker (glibenclamide).

   • According to Priyadarshini S (2019)

     Excerpt Conclusion: Thus, our results validate its traditional claim in the treatment of diabetes by stimulating the secretion of insulin, thereby suggesting a possible mechanism of its antidiabetic effect. The objective of this study was to establish the cytotoxicity profile & & to evaluate the insulin secretagogue effect of ethanolic root extract of Ravenala madagascariensis.

2. 2

   Cancer: adjuvant treatment of metastatic exocrine pancreatic carcinoma

   Plant part used: Sheet.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to Priyadarshini S (2020)

     Excerpt In the present study, the antitumor effect of successive ethanolic leaf extract over two human pancreatic cancer cell lines PANC1 & SW1990 was evaluated by MTT assay. Thus, the results validate the antitumor potential of RM leaf extract against pancreatic cancer a further study were aimed at the identification of active components responsible for the activity.

   • According to Sethuraman S (2020)

     Excerpt In the present study, the antitumor effect of successive ethanolic leaf extract over two human pancreatic cancer cell lines PANC1 & SW1990 was evaluated by MTT assay. madagascariensis , leaf extract against pancreatic cancer & further studies were aimed at the identification of active components responsible for the activity.

   • According to Beidokhti MN (2015)

     Excerpt The aim of this study was to assess whether inhibition of α-glucosidase [1] and α-amylase [2] by ethanol extracts of 40 Madagascarian plants is the scientific rationale behind their traditional anti-diabetic use.The ethanolic extracts were generally inactive against pancreatic α-amylase, & only bark extracts of Psidium guajava & Vangueria madagascariensis showed good activity with IC50 of 10.6 and 11.6 µg/mL, respectively. All active extracts had large amounts of tannins in the HPLC chromatogram, except aerial parts of Euphorbia hirta & leaves of Artocarpus heterophylla, Ravenala madagascariensis & Zanthoxylum tsihanimposa, which contained only low levels of tannins.

   • According to Priyadarshini S (2019)

     Excerpt The objective of this study was to establish the cytotoxicity profile & & to evaluate the insulin secretagogue effect of ethanolic root extract of Ravenala madagascariensis.

3. 3

   Fungal infection

   Plant part used: Sheet.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to Onifade AK (n.d.)

     Excerpt This study was done to investigate the antifungal & toxicological activities of extracts from the leaves of Ravenala madagascariensis.

Further indications (including other extraction modes where applicable), dosages, precautions for use, and the <strong>full scientific references</strong> (complete records, not only the short excerpts above) are available in the complete monographic record in the Lapo v2 application.