Salvia hispanica (Chia) : medicinal properties in alcoholic extraction

Salvia hispanica (Chia) — family Lamiacées.

Scientific synonyms : Kiosmina hispanica (L.) Raf., Salvia chia Colla, Salvia prysmatica Cav., Salvia schiedeana Stapf, Salvia tetragona Moench.

This database documents alcoholic (ethanol) extractions of active substances. Our monograph currently lists 7 indications in alcoholic extraction for this species. The Lapo v2 catalogue records 163 scientific references for this species (full detail in the application).

Important — scientific references on this public page: only a short excerpt of each cited source is shown (selected abstract sentences), kept in the original language of the publication (most often English), without translation. These excerpts are not the full article text and are not a complete bibliography. The full reference records and complete monographic detail are available in the Lapo v2 application (free 30-day trial).

1. 1

   Type II diabetes mellitus

   Plant part used: seed.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to AHMAD N (2025)

     Excerpt This study investigated the antioxidant & antidiabetic properties of an ethanolic extract of Salvia hispanica (chia) seeds in alloxan-induced diabetic mice. Diabetes mellitus (DM) is one of the most significant global health challenges, requiring urgent solutions to enhance its treatment efficacy & affordability.

   • According to RIVIERI-SALGADO GM (2024)

     Excerpt Interestingly, in the NL rats, the provision of the functional food produced some of the expected improvements in health, such as significant decreases in body weight gain & liver cholesterol&d non-significant decreases in adipose tissue & leptin & insulin serum levels.

   • According to Briceño-Islas G (2024)

     Excerpt CMPH represents an alternative to add value to the agri-food co-product of the chia seed oil industry, generating food ingredients with outstanding antidiabetic & antioxidant potential. This work investigated the biochemical, antidiabetic, antioxidant potential, & physicochemical properties of chia meal protein hydrolysate (CMPH).

   • According to Selma-Garcia R (2021)

     Excerpt We analyze the effects of the products on glycaemia & insulin resistance (HOMA-IR), plasmatic triglycerides, intestinal and hepatic gene expression & variations of myeloid (MY), & lymphoid (LY) cells population in peripheral blood. This study compares the effects of immunonutritional bioactives from Chenopodium quinoa (WQ) or Salvia hispanica L.

   • According to Tavera-Hernández R (2023)

     Excerpt The antidiabetic effects of chia are effective in different mechanisms involved in the complex pathogenesis of DM, including hypoglycemic, antioxidant, & anti-inflammatory mechanisms, & the inhibition of the enzymes α-glucosidase & α-amylase, as well as in the prevention of the risk of cardiovascular disease. Recent approaches propose treatments for DM based on that; in addition to focusing on reducing hyperglycemia, they also consider multitargets, as in the case of plants.

2. 2

   Bacterial infection: Acinetobacter baumannii, Aeromonas hydrophila, Bacillus subtilis, Escherichia coli, Staphylococcus aureus

   Plant part used: seed.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to Güzel S. (2020)

     Excerpt Ethanol extract of Chia seeds were tested against Staphylococcus aureus (ATCC 25925), Bacillus subtilis (ATCC 6633), Escherichia coli (ATCC 25923), Acinetobacter baumannii (ATCC 02026), Aeromonas hydrophila (ATCC 95080), Candida albicans (ATCC 14053), Candida tropicalis (ATCC 1369), & Candida glabrata (ATCC 15126) using broth microdilution method.

   • According to Motyka S (2023)

     Excerpt The purpose of this study was to evaluate the phytochemical profiles of the seeds, sprouts, leaves, flowers, roots & herb of Salvia hispanica & to demonstrate their significant contribution to antioxidant & antimicrobial activities. hispanica plant raw materials in terms of the profile of biologically active metabolites & their contribution to antioxidant, antimicrobial & antifungal activity.

   • According to Knez Hrnčič M (2020)

     Excerpt Chia (Salvia hispanica L.) is a small seed that comes from an annual herbaceous plant, Salvia hispanica L. In the present study, an extensive overview of the chemical composition, nutritional properties, & antioxidant & antimicrobial activities, along with extraction methods used to produce chia oil, will be discussed.

   • According to Knez Hrnčič M (2020)

     Excerpt Chia (Salvia hispanica L.) is a small seed that comes from an annual herbaceous plant, Salvia hispanica L. In the present study, an extensive overview of the chemical composition, nutritional properties, & antioxidant & antimicrobial activities, along with extraction methods used to produce chia oil, will be discussed.

   • According to Poulios E. (2020)

     Excerpt Common sage (Salvia spp., with the most common species Salvia officinalis) is an important medicinal & aromatic plant due to its bioactive components, secondary products of its metabolism.

3. 3

   Fungal: Candida albicans, C. glabrata, C. tropicalis

   Plant part used: seed.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to Knez Hrnčič M (2020)

     Excerpt Chia (Salvia hispanica L.) is a small seed that comes from an annual herbaceous plant, Salvia hispanica L. In the present study, an extensive overview of the chemical composition, nutritional properties, & antioxidant & antimicrobial activities, along with extraction methods used to produce chia oil, will be discussed.

   • According to Motyka S (2023)

     Excerpt The purpose of this study was to evaluate the phytochemical profiles of the seeds, sprouts, leaves, flowers, roots & herb of Salvia hispanica & to demonstrate their significant contribution to antioxidant & antimicrobial activities. hispanica plant raw materials in terms of the profile of biologically active metabolites & their contribution to antioxidant, antimicrobial & antifungal activity.

   • According to Knez Hrnčič M (2020)

     Excerpt Chia (Salvia hispanica L.) is a small seed that comes from an annual herbaceous plant, Salvia hispanica L. In the present study, an extensive overview of the chemical composition, nutritional properties, & antioxidant & antimicrobial activities, along with extraction methods used to produce chia oil, will be discussed.

   • According to Poulios E. (2020)

     Excerpt Common sage (Salvia spp., with the most common species Salvia officinalis) is an important medicinal & aromatic plant due to its bioactive components, secondary products of its metabolism.

   • According to Güzel S. (2020)

     Excerpt Ethanol extract of Chia seeds were tested against Staphylococcus aureus (ATCC 25925), Bacillus subtilis (ATCC 6633), Escherichia coli (ATCC 25923), Acinetobacter baumannii (ATCC 02026), Aeromonas hydrophila (ATCC 95080), Candida albicans (ATCC 14053), Candida tropicalis (ATCC 1369), & Candida glabrata (ATCC 15126) using broth microdilution method.

Further indications (including other extraction modes where applicable), dosages, precautions for use, and the <strong>full scientific references</strong> (complete records, not only the short excerpts above) are available in the complete monographic record in the Lapo v2 application.