Senna simaea (The Siamese Break-up) : medicinal properties in alcoholic extraction

Senna simaea (The Siamese Break-up, Casse de Siam) — family Fabacées.

Scientific synonyms : Cassia arayatensis "sensu Naves, Cassia arborea Mcfad, C Florida Vahl, C gigantea DC, C siamea Lam, C sumatrana Roxb, Cassia sumatrana DC, Chamaefistula gigantea C.Don, Sciacassia siamea (Lam.) Britton & Rose, Senna sumatrana (DC.) Roxb.

This database documents alcoholic (ethanol) extractions of active substances. Our monograph currently lists 12 indications in alcoholic extraction for this species. The Lapo v2 catalogue records 151 scientific references for this species (full detail in the application).

Important — scientific references on this public page: only a short excerpt of each cited source is shown (selected abstract sentences), kept in the original language of the publication (most often English), without translation. These excerpts are not the full article text and are not a complete bibliography. The full reference records and complete monographic detail are available in the Lapo v2 application (free 30-day trial).

1. 1

   Type II diabetes mellitus

   Plant part used: Sheet.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to Luangpirom A (2006)

     Excerpt This study concludes that SS leaf extract exhibits a hypoglycemic effect and antihyperglycemic effect in non-diabetic rats after induction of hyperglycemia with 2 g/kg bw. orally had significantly decreased blood glucose by 50.32 and 47.29 % per hour when compared with rats treated with insulin stimulating substance, glibenclamide (10 mg/kg bw.; P< 0.05).

   • According to Hassan IA (2015)

     Excerpt Hassan IA et al, Phytochemical studies & thin layer chromatography of leaves & flower extracts of Senna siamea Lam for possible biomedical applications, J of Pharmacogn & Phytother, 7(3):18-26, 2015-Abstact: Senna siamea is a medium-size, evergreen plant which has been utilized as a source of food, medicine & other agricultural purposes in different communities. From our findings, it can be concluded that SS contains some significant phytochemicals that can exhibit desired therapeutic activities such as hypoglycemia, anti-arrythmia & antimicrobial.

   • According to Abdulrasheed M (2015)

     Excerpt Findings therefore, recommend the use of SS leaf in the treatment of enteric fever in traditional medicine. This study was aimed at investigating the phytochemical constituents of ethanolic extract of Senna siamea leaf & also to determine its antimicrobial activity on some Enterobacteriaceae which include Escherichia coli, Proteus mirabilis & Klebsiella pneumonia, using agar disc diffusion method.

   • According to Dahiru D (2013)

     Excerpt The study confirms the use of SS leaf in the treatment of enteric fever in traditional medicine in different parts of the world. This study evaluated the antimicrobial activity of different extracts (acetone, ethanol & water) & ethanol fractions (chloroform, ethyl acetate & n-butanol) of Senna siamea leaf on selected microorganisms, Escherichia coli,Staphylococcus aureus, Klebsiella pneumonia, Pseudomonas aeruginosa & Salmonella typhi using the agar well diffusion method.

   • According to Author (2009)

     Excerpt Morales M.A., Is Senna laxative use associated to cathartic colon, genotoxicity, or carcinogenicity?

2. 2

   Vascular disorders associated with type II diabetes, endothelial dysfunction,

   Plant part used: Sheet.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to Luangpirom A (2006)

     Excerpt This study concludes that SS leaf extract exhibits a hypoglycemic effect and antihyperglycemic effect in non-diabetic rats after induction of hyperglycemia with 2 g/kg bw. orally had significantly decreased blood glucose by 50.32 and 47.29 % per hour when compared with rats treated with insulin stimulating substance, glibenclamide (10 mg/kg bw.; P< 0.05).

   • According to Hassan IA (2015)

     Excerpt Hassan IA et al, Phytochemical studies & thin layer chromatography of leaves & flower extracts of Senna siamea Lam for possible biomedical applications, J of Pharmacogn & Phytother, 7(3):18-26, 2015-Abstact: Senna siamea is a medium-size, evergreen plant which has been utilized as a source of food, medicine & other agricultural purposes in different communities. From our findings, it can be concluded that SS contains some significant phytochemicals that can exhibit desired therapeutic activities such as hypoglycemia, anti-arrythmia & antimicrobial.

   • According to Author (2009)

     Excerpt Morales M.A., Is Senna laxative use associated to cathartic colon, genotoxicity, or carcinogenicity?

3. 3

   Bacterial infection: Escherichia coli, Staphylococcus aureus, Klebsiella pneumoniae, Proteus mirabilis, Pseudomonas aeruginosa

   Plant part used: Sheet.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to Dahiru D (2013)

     Excerpt This study evaluated the antimicrobial activity of different extracts (acetone, ethanol & water) & ethanol fractions (chloroform, ethyl acetate & n-butanol) of Senna siamea leaf on selected microorganisms, Escherichia coli,Staphylococcus aureus, Klebsiella pneumonia, Pseudomonas aeruginosa & Salmonella typhi using the agar well diffusion method.

   • According to Abdulrasheed M (2015)

     Excerpt This study was aimed at investigating the phytochemical constituents of ethanolic extract of Senna siamea leaf & also to determine its antimicrobial activity on some Enterobacteriaceae which include Escherichia coli, Proteus mirabilis & Klebsiella pneumonia, using agar disc diffusion method. Microorganisms are known to cause different types of infection in both humans and animals.

   • According to Bukar A (2009)

     Excerpt Bukar A et al, Phytochemical screening & antibacterial activity of leaf extracts of Senna siamea (Lam) on Pseudomonas aeruginosa.

Further indications (including other extraction modes where applicable), dosages, precautions for use, and the <strong>full scientific references</strong> (complete records, not only the short excerpts above) are available in the complete monographic record in the Lapo v2 application.