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Spirulina platensis : medicinal properties in alcoholic extraction

Spirulina platensis (Spiruline) — family Cyanophycées.

Scientific synonyms : Arthrospira laxíssima-Set, A máxima, A miniata-G, A patensis-GBD, pellucida-CW, A spirulinoides-(R)-D.., A tenuis-B & B..

This database documents alcoholic (ethanol) extractions of active substances. Our monograph currently lists 4 indications in alcoholic extraction for this species. The Lapo v2 catalogue records 138 scientific references for this species (full detail in the application).

Therapeutic indications in alcoholic extraction:

Important — scientific references on this public page: only a short excerpt of each cited source is shown (selected abstract sentences), kept in the original language of the publication (most often English), without translation. These excerpts are not the full article text and are not a complete bibliography. The full reference records and complete monographic detail are available in the Lapo v2 application (free 30-day trial).

  1. Cancer: adjuvant treatment for colorectal and liver cancer

    Plant part used: leaf.

    Scientific references (short excerpts)

    Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

    • According to Al-Saily HMN (2024)

      Excerpt The aim of current study to evaluate the cytotoxicity of SP extracts on colon cancer (CaCo-2), hepatic cancer (HepG2) cell lines, normal fibroblast cells line (HdFn) & also antioxidant activity. Spirulina platensis is blue-green algae received significant attention for its high nutritional value, it is a source of powerful antioxidants.

    • According to Intikhab A (2023)

      Excerpt This makes Spirulina a promising functional food for the treatment of ailments like diabetes, cancer, cardiovascular disorders (CVDs), COVID-19, neuro-inflammatory conditions & gut dysbiosis. Studies included in this review have suggested spirulina to be a rich source of complete proteins, essential fatty acids (EFAs), vitamins, minerals & various bioactive compounds like carotenoids, chlorophyll, & xanthophylls.

    • According to Zaid A.A.A (2015)

      Excerpt Therefore, the aim of the present study is to determine antioxidant activity of Spirulina platensis water extracts and their cytotoxicity against cell lines {colon carcinoma cells (HCT116) and hepatocellular carcinoma cells (HEPG2)}. One of its species Spirulina platensis or its extract showed therapeutic properties, such as the ability to prevent cancers, decrease blood cholesterol level, reduce nephrotoxicity of pharmaceuticals and toxic metals & provide protection against the harmful effect of radiation.

    • According to Wu LC (2005)

      Excerpt The growth inhibitory effects of aqueous spirulina and chlorella extract on human liver cancer cells, HepG2, were also studied and compared in pairs. A potential treatment for liver fibrosis is to inhibit activated hepatic stellate cell (HSC) proliferation &, subsequently, to induce HSC apoptosis.

    • According to Wan XZ (2019)

      Excerpt The contributions to hypoglycemic function & gut microbiota regulation by water & ethanol extracts of the microalgae Chlorella pyrenoidosa & Spirulina platensis were determined. platensis supplementation increased the abundance of Oscillibacter, Pasteurella, & Alloprevotella & decreased the abundance of Turicibacter.

  2. Type II diabetes mellitus

    Plant part used: leaf.

    Scientific references (short excerpts)

    Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

    • According to Wan XZ (2019)

      Excerpt The contributions to hypoglycemic function & gut microbiota regulation by water & ethanol extracts of the microalgae Chlorella pyrenoidosa & Spirulina platensis were determined. Thus, CP55 & SP55 may be developed as effective natural food materials for preventing diabetes, & Ruminococcus may play a vital role in the treatment of diabetes.

    • According to Intikhab A (2023)

      Excerpt This makes Spirulina a promising functional food for the treatment of ailments like diabetes, cancer, cardiovascular disorders (CVDs), COVID-19, neuro-inflammatory conditions & gut dysbiosis. Studies included in this review have suggested spirulina to be a rich source of complete proteins, essential fatty acids (EFAs), vitamins, minerals & various bioactive compounds like carotenoids, chlorophyll, & xanthophylls.

    • According to Mazo VK (2022)

      Excerpt Hypoglycemic effects are shown in particular in experiments on rats with hyperlipidemia & alloxan diabetes fed a diet enriched with AP biomass & on KKAy mice, treated with C-phycocyanin extract. Search keywords: Arthrospira platensis, phycobiliprotein, C-phycocyanin, allo-phycocyanin, hypoglycemic effect, hypolipidemic effect, antioxidant activity, in vitro &in vivo studies.

    • According to Ansari R (2023)

      Excerpt Moreover, Spirulina's positive influence on several organs, including hair, skin, liver, CNS, lung, & genitourinary tract, are ascribed to different components of various species of Spirulina such as Spirulina platensis, S fusiformis, & S maxima.

    • Excerpt According to this review, antioxidative, anti-inflammatory, anti-neoplastic, hypolipidemic, antiviral, immunomodulatory, antimicrobial, anti-atherogenic, anti-diabetic, & radio-protective functions are attributed to Spirulina.

    • According to Ramzi G.A (2015)

      Excerpt To determine the composition of flaxseed oil and Spirulina platensis oil and to evaluate their biological activities either alone or in combination by in-vitro studies. platensis oil & flaxseed oil does not have any synergistic properties, indeed the combination of oils induced antagonistic effects on their biological properties.

Further indications (including other extraction modes where applicable), dosages, precautions for use, and the <strong>full scientific references</strong> (complete records, not only the short excerpts above) are available in the complete monographic record in the Lapo v2 application.

Evolution of this plant record

Under the CTA · public change history

Content

+3 references · ~1 reference corrected · −3 references

Counts and domains only: indication labels and synergy names are not listed here (open the in-app plant file). Bibliographic texts for new, corrected, or removed references expand below.

+3 references~1 reference corrected−3 references
+3 references — show text
Chaudhary K et al, Ultrasound assisted natural deep eutectic solvents based sustainable extraction of Spirulina platensis & orange peel extracts for the development of strawberry-cantaloupe based noveChaudhary K · 2025

Chaudhary K et al, Ultrasound assisted natural deep eutectic solvents based sustainable extraction of Spirulina platensis & orange peel extracts for the development of strawberry-cantaloupe based novel clean-label functional drink, Ultrason Sono Chem, 118:107357, 2025-Abstract: The objective of the research was to develop novel ready-to-serve clean-label functional drink formulations by blending strawberry & cantaloupe juices (35 % each), with the addition of Spirulina platensis and orange peel extracts as clean-label functional ingredients, either alone or in combination, at concentrations…

Added
SHEHAB NG et al, Phytochemical Evaluation of Lepidium meyenii, Trigonella foenum-graecum, Spirulina platensis, & Tribulus arabica, & Their Potential Effect on Monosodium Glutamate Induced Male ReproduSHEHAB NG · 2024

SHEHAB NG et al, Phytochemical Evaluation of Lepidium meyenii, Trigonella foenum-graecum, Spirulina platensis, & Tribulus arabica, & Their Potential Effect on Monosodium Glutamate Induced Male Reproductive Dysfunction in Adult Wistar Rats, Antioxidants (Basel), 13(8):939. 2024-Abstract: Monosodium glutamate (MSG), a sodium salt derived from glutamic acid, is widely used in commercial food products to improve taste, quality, & preservation. However, its consumption may have detrimental effects on male reproductive function. Nevertheless, plant extracts, such as Lepidium meyenii (Maca), Trigo…

Added
TAITI C et al, Addition of Spirulina to Craft Beer: Evaluation of the Effects on Volatile Flavor Profile & Cytoprotective Properties, Antioxidants (Basel), 12(5) :1021, 2023-Abstract: SPME-GC-MS & PTRTAITI C · 2023

TAITI C et al, Addition of Spirulina to Craft Beer: Evaluation of the Effects on Volatile Flavor Profile & Cytoprotective Properties, Antioxidants (Basel), 12(5) :1021, 2023-Abstract: SPME-GC-MS & PTR-ToF-MS techniques were applied to describe the content of volatile flavor compounds in a craft beer before & after adding spirulina. The obtained results showed that the volatile profile of the two beer samples differed. Furthermore, to chemically characterize biomass spirulina, a derivatization reaction followed by GC-MS analysis was performed, highlighting a high content of molecules belongi…

Added
Machowiec P et al, Effect of Spirulina Supplementation on Systolic & Diastolic Blood Pressure: Systematic Review & Meta-Analysis of Randomized Controlled Trials. Nutr, 13(9):3054, 2021-Machowiec P · 2021

Machowiec P et al, Effect of Spirulina Supplementation on Systolic & Diastolic Blood Pressure: Systematic Review & Meta-Analysis of Randomized Controlled Trials. Nutr, 13(9):3054, 2021-

Corrected
Andrica FM et al, acute oral & dermal effects of Spirulina in lice, Phytother, 2018ABSTRACT: Spirulina (SP) is a spiral-shaped, blue-green microalga included in bacteria kingdom. SP has a rich contentAndrica FM · 2000

Andrica FM et al, acute oral & dermal effects of Spirulina in lice, Phytother, 2018ABSTRACT: Spirulina (SP) is a spiral-shaped, blue-green microalga included in bacteria kingdom. SP has a rich content in essential amino acids, phycobiliproteins (phycoerythrin, phycocyanin), minerals, vitamins, carotenoids, polyphenols & essential fatty acids. The aim of this study consists in a safety evaluation of SP treatment using oral & dermal toxicity studies. SP has revealed no significant changes in skin parameters, behavior or other locomotion problems when was administered at limited doses of 2000 …

Removed
Arguelles-Velazquez et al, Amelioration of cadmium-produced teratogenicity & genotoxicity in mice given Arthrospira maxima (Spirulina) treatment. Evid Based Complement Alternat Med. 2013:1–8-Abstract:Arguelles-Velazquez · 2013

Arguelles-Velazquez et al, Amelioration of cadmium-produced teratogenicity & genotoxicity in mice given Arthrospira maxima (Spirulina) treatment. Evid Based Complement Alternat Med. 2013:1–8-Abstract: Evaluation of the effects of Arthrospira maxima (AM) was made, otherwise known as Spirulina, on the teratogenicity, genotoxicity, & DNA oxidation processes induced by cadmium (Cd). Pregnant ICR mice were divided into groups & administered water, Cd only, AM only, or AM plus Cd. AM was administered orally at doses of 200, 400, & 800 mg/kg from gestational day 0 (GD0) to GD17, and at GD7 there w…

Removed
Mohammadi M et al, Encapsulation of Spirulina protein hydrolysates in liposomes: Impact on antioxidant activity & gastrointestinal behavior. Food Chem.2023, 400, 133973-Abstract:Mohammadi M · 2023

Mohammadi M et al, Encapsulation of Spirulina protein hydrolysates in liposomes: Impact on antioxidant activity & gastrointestinal behavior. Food Chem.2023, 400, 133973-Abstract:

Removed

By Emmanuel Nossin · ethnopharmacologist

Content

First public publication

New planttop 3 · ref count

By Emmanuel Nossin · ethnopharmacologist