Spondias mombin : medicinal properties in alcoholic extraction

Spondias mombin (Mouben, Mombinn) — family Anacardiacées.

Scientific synonyms : Myrobolan Lutea-Macfad, Spondias ciroulella-A non Tussac, S. lutea-L, S. lutea-Salisb.

Recognised external sources linked to this monograph: TRAMIL.

This database documents alcoholic (ethanol) extractions of active substances. Our monograph currently lists 29 indications in alcoholic extraction for this species. The Lapo v2 catalogue records 81 scientific references for this species (full detail in the application).

Important — scientific references on this public page: only a short excerpt of each cited source is shown (selected abstract sentences), kept in the original language of the publication (most often English), without translation. These excerpts are not the full article text and are not a complete bibliography. The full reference records and complete monographic detail are available in the Lapo v2 application (free 30-day trial).

1. 1

   Cancer: adjuvant treatment for hepatocellular carcinoma

   Plant part used: stem bark.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to Lawal R (2022)

     Excerpt The present study investigated the effect of the administration of Spondias mombin ethanolic stem-bark extract on tumor marker, cytokine mediators, protein, & albumin levels in DEN-induced liver cancer in male Wistar rats. Diethylnitrosamine (DEN) is a common rat model used in the study of the mechanism of chemical carcinogenesis & the response of Hepatocellular carcinoma (HCC) to anticancer drug therapy.

   • According to ASUQUO OR (2013)

     Excerpt The haematinic potential of ethanol extract of Spondias mombin leaves was investigated in female Wistar rats. The liver of experimental groups showed no significant change compared to control.

   • According to Asuquo OR (2012)

     Excerpt Conclusion: This result suggests that although the use of the leaf extracts of S mombin is relatively safe, hepatic & renal toxicity may occur with prolonged use. Spondias mombin is relied on for various herbal remedies for numerous conditions.

   • According to Iweala E (2011)

     Excerpt The aim of this study was to evaluate the individual and synergistic hypoglycaemic and biochemical effects of the ethanolic extracts of seeds of Parinari Polyandra & Spondias mombin in alloxan-induced diabetic rats. The histological changes showed the presence of fatty cells in the liver of alloxan-induced diabetic control & non diabetic rats administered both P Polyandra & S mombin extracts.

   • According to Almeida CORP (2024)

     Excerpt In vitro & in vivo studies indicate that these bioactive compounds have several health benefits related to the prevention or treatment of diseases, including antioxidant effects; anti-inflammatory effects; & antidiabetic, antidepressant, neuroprotective, antiproliferative, anticancer, hypolipemic, cardioprotective, gastroprotective, hepatoprotective, & nephroprotective effects,& they are particularly related to the reduction of damage from oxidative stress. Murici (Byrsonima crassifolia) & Taperebá (Spondias mombin) are sources of vitamins, minerals, & phytochemicals with potential health benefits.

2. 2

   Type II diabetes mellitus

   Plant part used: stem bark.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to Akinlolu AA (2011)

     Excerpt A significant decrease (P<0.05) in alloxan-induced hyperglycemia attaining near normalization, as well as significant hypotriglyceridemia (P<0.05) after 4 weeks of extract therapy were observed. These data appear to justify the antihyperglycaemic, hypolipidemic & protective potential for most organs by Spondias mombin.

   • According to Iweala E (2011)

     Excerpt The aim of this study was to evaluate the individual and synergistic hypoglycaemic and biochemical effects of the ethanolic extracts of seeds of Parinari Polyandra & Spondias mombin in alloxan-induced diabetic rats. The ethanolic extracts of the seeds of P Polyandra & S mombin were obtained by Soxhlet extraction and administered to nondiabetic & alloxan-induced diabetic albino rats.

   • According to Akwu BP (2022)

     Excerpt This work aimed at investigating the effects of co-administration of Spondias mombin & metformin in STZ-induced hyperglycemia & hepatorenal injury in the Wistar rat model, specifically focusing on the morphological, biochemical, & immunohistochemical alterations in the liver & kidney. As a result of its many therapeutic properties, including its potent anti-hyperglycemic effect, the Spondias mombin plant is quickly gaining popularity as a local therapeutic agent for the treatment of many ailments.

   • According to Almeida CORP (2024)

     Excerpt Murici (Byrsonima crassifolia) & Taperebá (Spondias mombin) are sources of vitamins, minerals, & phytochemicals with potential health benefits. In vitro & in vivo studies indicate that these bioactive compounds have several health benefits related to the prevention or treatment of diseases, including antioxidant effects; anti-inflammatory effects; & antidiabetic, antidepressant, neuroprotective, antiproliferative, anticancer, hypolipemic, cardioprotective, gastroprotective, hepatoprotective, & nephroprotective effects,& they are particularly related to the reduction of damage from oxidative stress.

   • According to Gobinath R (2022)

     Excerpt Gobinath R et al, Antidiabetic & antihyperlipidemic effects of methanolic extract of leaves of Spondias mombin in streptozotocin-induced diabetic rats.

3. 3

   Wounds, erysipelas, erythema, psoriasis, candidiasis: traditional gel formulation

   Plant part used: leaf.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to Garcia de Oliveira KM (2020)

     Excerpt These results suggest that S.M stem has topical anti-inflammatory activity, which supports the traditional uses & may represent an alternative for the treatment of cutaneous inflammation. Spondias mombin is a medicinal plant traditionally used for the treatment of vomiting, diarrhea, hemorrhoids, wounds & inflammation.

   • According to TEMIDAYO A (2026)

     Excerpt However, treatment with Donepezil & ELESM 200 mg/kg, 400 mg/kg & 600 mg/kg produced significant anticholinesterase, antioxidant, & anti-inflammatory effects, restoring these protein levels to near normal. Previous studies have demonstrated that phytochemicals present in Spondias mombin leaves possess neuro-regenerative & neuroprotective potentials.

   • According to Almeida CORP (2024)

     Excerpt In vitro & in vivo studies indicate that these bioactive compounds have several health benefits related to the prevention or treatment of diseases, including antioxidant effects; anti-inflammatory effects; & antidiabetic, antidepressant, neuroprotective, antiproliferative, anticancer, hypolipemic, cardioprotective, gastroprotective, hepatoprotective, & nephroprotective effects,& they are particularly related to the reduction of damage from oxidative stress. Murici (Byrsonima crassifolia) & Taperebá (Spondias mombin) are sources of vitamins, minerals, & phytochemicals with potential health benefits.

   • According to Metibemu DS (2020)

     Excerpt Metibemu DS et al, Carotenoid isolates of Spondias mombin demonstrate anticancer effects in DMBA-induced breast cancer in Wistar rats through X-linked inhibitor of apoptosis protein (XIAP) antagonism & anti-inflammation.

   • According to Ogunro OB (2023)

     Excerpt this study was designed to investigate the redox-regulation capacity of Spondias mombin leaf fraction rich in Quercetin-3-O-β-D-glucopyranoside (Q3G-RF) in rat model of dichlorvos (DDVP) toxicity. Conclusion : Q3G-RF reversed the induced oxidative stress & inflammation as well as suppressed sperm function & reproductive parameters caused by dichlorvos, suggesting the exploration as a therapeutic agent in managing male fertility disorders.

Further indications (including other extraction modes where applicable), dosages, precautions for use, and the <strong>full scientific references</strong> (complete records, not only the short excerpts above) are available in the complete monographic record in the Lapo v2 application.