Tylophora indica (Lépika -mawon) : medicinal properties in alcoholic extraction

Tylophora indica (Lépika -mawon, Brown ipéca, Ipéca marron) — family Asclépiadacées.

Scientific synonyms : Cynanchum indicum-Burm f., Asclepias athsmatica-L.f., Tylophora asthmatica-(L.f.)-Wright & Arn.

This database documents alcoholic (ethanol) extractions of active substances. Our monograph currently lists 14 indications in alcoholic extraction for this species. The Lapo v2 catalogue records 58 scientific references for this species (full detail in the application).

Important — scientific references on this public page: only a short excerpt of each cited source is shown (selected abstract sentences), kept in the original language of the publication (most often English), without translation. These excerpts are not the full article text and are not a complete bibliography. The full reference records and complete monographic detail are available in the Lapo v2 application (free 30-day trial).

1. 1

   Type II diabetes mellitus

   Plant part used: Sheet.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to Swathi P (2020)

     Excerpt The objective of the study is to evaluate the ethanolic leaf extract of Tylophora indica (ELTI) on pancreatic & hepatic oxidative stress in streptozotocin (STZ) induced diabetic rats. The activities of antioxidant enzymes superoxide dismutase (SOD), catalase (CAT), glutathione peroxidase (GPx), glutathione-S- transferase (GST) & the levels of reduced glutathione (GSH) were also decreased, while an increase in the levels of thiobarbituric acid reactive substances (TBARS) were observed in pancreas & liver with ELTI treatment in STZ induced diabetic rats.

   • According to Swathi P (2012)

     Excerpt This study was undertaken to investigate the effect of ethanolic extract of Tylophora indica (Asclepiadaceae) leafs on blood glucose levels & other biochemical parameters in alloxone (120 mg/kg. Simultaneously, the alteration in lipid metabolism was partially attenuated as evidenced by decreased serum total cholesterol (TC), triglyceride (TG) & low-density lipoprotein cholesterol (LDL) levels & by increased high-density lipoprotein cholesterol (HDL) concentration in diabetic rat (p < 0.001).

   • According to Nazar S (2020)

     Excerpt Tylophora indica, a threatened medicinal plant of family Asclepiadaceae, grows profoundly in Asia, Africa, Australia, Oceanic Islands, Ceylon, Malay Island, & Borneo. Antidiabetic, hepatoprotective, antiangiogenic, anti-tumor, antioxidant, anticonvulsant, anti-rheumatic, & diuretic activities are also attributed to the magnificent medicinal plant owing to the occurrence of various active phytochemicals such as alkaloids, saponins, phytosterols, tannins, & primary metabolites.

2. 2

   Liver disorders: cirrhosis, hepatitis, fatty liver disease

   Plant part used: Sheet.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to Jahas J (2014)

     Excerpt : The hepatoprotective role of Tylophora indica ethanolic extract was studied on artesunate induced liver injury in wistar albino rats. Conclusions: The present study proves that the ethanolic extract of Tylophora indica has a significant protective action against artesunate induced hepatic injury.

   • According to Gujrati V (2018)

     Excerpt To investigate the hepatoprotective activity of alcoholic (ALLT) & aqueous (AQLT) extracts of leaves of Tylophora indica (asclepiadaceae) against ethanol-induced hepatotoxicity. Materials & Methods: Leaf powder of Tylophora indica was successively extracted with alcohol & water.

   • According to Dikshith T (1990)

     Excerpt Activities of glutamic oxaloacetic transaminase, glutamic pyruvic transaminase and alkaline phosphatase were significant and associated with morphological changes in liver.

   • According to Cyriac A (2020)

     Excerpt Tylophora indica, a medicinal climber, belongs to the family, Asclepiadaceae. The major alkaloid, tylophorine found in TI possesses several properties, such as immunosuppressive, antitumour, antifeedant, antibacterial, antifungal, antiamoebic, diuretic & hepatoprotective activities.

   • According to Khurana S (2019)

     Excerpt Antmool (Tylophora indica (Burm.

3. 3

   High blood pressure, fluid retention, oedema

   Plant part used: Sheet.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to Vivean P (2015)

     Excerpt It has been used for the treatment of bronchial asthma, jaundice, inflammation, smooth muscle relaxant, antihistaminic, hypotensive, anti-rheumatic activities which were scientifically proven. Our aim of the present review is to explore the traditional use of Tylophora indica.

   • According to Ganguly T (2001)

     Excerpt Crude extract of the leaves of Tylophora indica inhibited delayed hypersensitivity reaction to sheep red blood cells in rats when the alkaloid mixture was administered before & after immunization with these cells. Tylophora alkaloids have been shown to have antiasthmatic, antiinflammatory & antianaphylactic properties.

   • According to Balasubramanian B (2010)

     Excerpt Tylophora indica is an extensively used Indian traditional medicine to cure various human ailments, & acts as a folk remedy for the treatment of bronchial asthma, inflammation, bronchitis, allergies, rheumatism & dermatitis. Methanolic leaf extract of Tylophora indica showed highest inhibitory activity when compared with all treatments.

   • According to Raj CD (2006)

     Excerpt The objective of present study is to investigate the anti-inflammatory effect of Tylophora indica on Carrageenin induced hind paw oedema & cotton pellet granuloma in Albino rats. Tylophora indica produced significant anti-inflammatory effect in both acute & sub-acute models of inflammation was more effective when compared to Indomethacin.

   • According to Gururani R (2020)

     Excerpt Material & methods: Comprehensive information regarding TI was collected using the keywords Tylophora indica or Indian ipecac or ananthamool in various electronic databases ACS, Google Scholar, PubMed, Science Direct, SciFinder, Web of Science, Springer Link & Wiley. Tylophora indica (Burm.

Further indications (including other extraction modes where applicable), dosages, precautions for use, and the <strong>full scientific references</strong> (complete records, not only the short excerpts above) are available in the complete monographic record in the Lapo v2 application.