Tylophora indica (Lépika -mawon) : vertus médicinales en extraction alcoolique

Tylophora indica (Lépika -mawon, Ipéca marron, Brown ipéca) — famille Asclépiadacées.

Synonymes scientifiques : Cynanchum indicum-Burm f., Asclepias athsmatica-L.f., Tylophora asthmatica-(L.f.)-Wright & Arn.

Cette base documente les extractions alcooliques (éthanol) des substances actives. Notre monographie recense actuellement 14 indications en extraction alcoolique pour cette espèce. Le catalogue Lapo v2 enregistre 58 références scientifiques pour cette espèce (détail intégral dans l’application).

Important — références scientifiques sur cette page publique : seuls de courts extraits de chaque source citée sont présentés (phrases d’abstract sélectionnées), conservés dans leur langue d’origine (le plus souvent l’anglais), sans traduction. Ces extraits ne constituent pas le texte intégral de l’article ni une bibliographie complète. Les fiches de référence complètes et le détail monographique sont disponibles dans l’application Lapo v2 (essai gratuit 30 jours).

1. 1

   Diabète mellitus de type II

   Partie usitée : Feuille.

   Références scientifiques (courts extraits)

   Courts extraits uniquement (pas le texte intégral de l’article). Fiches de référence complètes dans l’application Lapo v2.

   • Selon Swathi P (2020)

     Extrait The objective of the study is to evaluate the ethanolic leaf extract of Tylophora indica (ELTI) on pancreatic & hepatic oxidative stress in streptozotocin (STZ) induced diabetic rats. The activities of antioxidant enzymes superoxide dismutase (SOD), catalase (CAT), glutathione peroxidase (GPx), glutathione-S- transferase (GST) & the levels of reduced glutathione (GSH) were also decreased, while an increase in the levels of thiobarbituric acid reactive substances (TBARS) were observed in pancreas & liver with ELTI treatment in STZ induced diabetic rats.

   • Selon Swathi P (2012)

     Extrait This study was undertaken to investigate the effect of ethanolic extract of Tylophora indica (Asclepiadaceae) leafs on blood glucose levels & other biochemical parameters in alloxone (120 mg/kg. Simultaneously, the alteration in lipid metabolism was partially attenuated as evidenced by decreased serum total cholesterol (TC), triglyceride (TG) & low-density lipoprotein cholesterol (LDL) levels & by increased high-density lipoprotein cholesterol (HDL) concentration in diabetic rat (p < 0.001).

   • Selon Nazar S (2020)

     Extrait Tylophora indica, a threatened medicinal plant of family Asclepiadaceae, grows profoundly in Asia, Africa, Australia, Oceanic Islands, Ceylon, Malay Island, & Borneo. Antidiabetic, hepatoprotective, antiangiogenic, anti-tumor, antioxidant, anticonvulsant, anti-rheumatic, & diuretic activities are also attributed to the magnificent medicinal plant owing to the occurrence of various active phytochemicals such as alkaloids, saponins, phytosterols, tannins, & primary metabolites.

2. 2

   Troubles hépatiques : cirrhose, hépatite, stéatose hépatique

   Partie usitée : Feuille.

   Références scientifiques (courts extraits)

   Courts extraits uniquement (pas le texte intégral de l’article). Fiches de référence complètes dans l’application Lapo v2.

   • Selon Jahas J (2014)

     Extrait : The hepatoprotective role of Tylophora indica ethanolic extract was studied on artesunate induced liver injury in wistar albino rats. Conclusions: The present study proves that the ethanolic extract of Tylophora indica has a significant protective action against artesunate induced hepatic injury.

   • Selon Gujrati V (2018)

     Extrait To investigate the hepatoprotective activity of alcoholic (ALLT) & aqueous (AQLT) extracts of leaves of Tylophora indica (asclepiadaceae) against ethanol-induced hepatotoxicity. Materials & Methods: Leaf powder of Tylophora indica was successively extracted with alcohol & water.

   • Selon Dikshith T (1990)

     Extrait Activities of glutamic oxaloacetic transaminase, glutamic pyruvic transaminase and alkaline phosphatase were significant and associated with morphological changes in liver.

   • Selon Cyriac A (2020)

     Extrait Tylophora indica, a medicinal climber, belongs to the family, Asclepiadaceae. The major alkaloid, tylophorine found in TI possesses several properties, such as immunosuppressive, antitumour, antifeedant, antibacterial, antifungal, antiamoebic, diuretic & hepatoprotective activities.

   • Selon Khurana S (2019)

     Extrait Antmool (Tylophora indica (Burm.

3. 3

   HTA, rétention hydrique, œdème

   Partie usitée : Feuille.

   Références scientifiques (courts extraits)

   Courts extraits uniquement (pas le texte intégral de l’article). Fiches de référence complètes dans l’application Lapo v2.

   • Selon Vivean P (2015)

     Extrait It has been used for the treatment of bronchial asthma, jaundice, inflammation, smooth muscle relaxant, antihistaminic, hypotensive, anti-rheumatic activities which were scientifically proven. Our aim of the present review is to explore the traditional use of Tylophora indica.

   • Selon Ganguly T (2001)

     Extrait Crude extract of the leaves of Tylophora indica inhibited delayed hypersensitivity reaction to sheep red blood cells in rats when the alkaloid mixture was administered before & after immunization with these cells. Tylophora alkaloids have been shown to have antiasthmatic, antiinflammatory & antianaphylactic properties.

   • Selon Balasubramanian B (2010)

     Extrait Tylophora indica is an extensively used Indian traditional medicine to cure various human ailments, & acts as a folk remedy for the treatment of bronchial asthma, inflammation, bronchitis, allergies, rheumatism & dermatitis. Methanolic leaf extract of Tylophora indica showed highest inhibitory activity when compared with all treatments.

   • Selon Raj CD (2006)

     Extrait The objective of present study is to investigate the anti-inflammatory effect of Tylophora indica on Carrageenin induced hind paw oedema & cotton pellet granuloma in Albino rats. Tylophora indica produced significant anti-inflammatory effect in both acute & sub-acute models of inflammation was more effective when compared to Indomethacin.

   • Selon Gururani R (2020)

     Extrait Material & methods: Comprehensive information regarding TI was collected using the keywords Tylophora indica or Indian ipecac or ananthamool in various electronic databases ACS, Google Scholar, PubMed, Science Direct, SciFinder, Web of Science, Springer Link & Wiley. Tylophora indica (Burm.

D’autres indications (y compris d’autres modes d’extraction le cas échéant), posologies, précautions d’emploi et les <strong>références scientifiques complètes</strong> (fiches intégrales, pas seulement les courts extraits ci-dessus) sont disponibles dans la fiche monographique de l’application Lapo v2.