Vetiveria zizanioides (Vetiver) : medicinal properties in alcoholic extraction

Vetiveria zizanioides (Vetiver, Vétivè) — family Poacées.

Scientific synonyms : andropogon zizanioïdes-Urb, A. squarrosus-L.f, A. Muricata-Retz, Anethum ziznioides-Hictch & Chase, Chrysopogon zizanioïdes-(L)-Roberty, Phalaris zizanioïdes-L..

Recognised external sources linked to this monograph: TRAMIL.

This database documents alcoholic (ethanol) extractions of active substances. Our monograph currently lists 15 indications in alcoholic extraction for this species. The Lapo v2 catalogue records 49 scientific references for this species (full detail in the application).

Important — scientific references on this public page: only a short excerpt of each cited source is shown (selected abstract sentences), kept in the original language of the publication (most often English), without translation. These excerpts are not the full article text and are not a complete bibliography. The full reference records and complete monographic detail are available in the Lapo v2 application (free 30-day trial).

1. 1

   Type II diabetes mellitus

   Plant part used: leaf.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to KUMAR KS (2013)

     Excerpt To evaluate the antihyperglycaemic activity of the ethanol extract of roots of Vetiveria zizanioïdes in alloxan induced diabetic rats. zizanioïdes (100, 250, 500 & 750 mg/kg p.w.o) significantly reduced the blood-glucose level at the end of 28th days in alloxan induced diabetes rats.

   • According to Kandsi F (2024)

     Excerpt Vetiveria zizanioides, known as vetiver grass, is renowned for its ecological significance in soil erosion control & the restoration of lands polluted by heavy metals. This study underscores the prominent attributes of EoVZ, particularly its antimicrobial & antidiabetic properties, suggesting its potential as a natural and effective agent ensuring high safety standards for public health.

2. 2

   Adjuvant treatment for breast cancer

   Plant part used: leaf.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to Chou ST (2012)

     Excerpt VZ-EO may suppress the inflammatory responses of LPS-stimulated RAW 264.7 macrophages, including nitric oxide production and cell apoptosis, by regulating the expression of the inflammation-related enzymes heme oxygenase-1, inducible nitric oxide synthase & cyclo-oxygenase-2 (inducible cyclooxygenase) & the inflammatory cytokines tumour necrosis factor-α, interleukin-1β & interferon-β.

   • According to HAN X (2017)

     Excerpt VEO exhibited strong antiproliferative activity in these cells and significantly inhibited the production of collagen III, an important molecule for skin & tissue remodeling processes. Vetiver (Vetiveria zizanioïdes) essential oil (VEO) has a long history of use.

   • According to Prehandini A (2018)

     Excerpt The fragrant root (Vetiveria zizanioïdes Linn) is known to have anticancer activity.

   • According to Seshadri VD (2020)

     Excerpt Plants such as, Vetiveria zizanoides, Trichosanthes cucumerina, & Mollugo cerviana were collected from Western Ghats, Tamilnadu, India.

   • According to GLORY JL (2015)

     Excerpt Both Vetiveria zizanioïdes & Foeniculum vulgare are the common source of the well known oil, particularly used in aromatherapy and regarded as a tonic to the nervous system. Vetiveria zizanioïdes (100mg/kg) & Foeniculum vulgare (200mg/kg) produced significant antidepressant effect by reduction in immobility period as compared to control.

3. 3

   Gastric ulcer

   Plant part used: leaf.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to SURALKAR A (2015)

     Excerpt The ethanolic extract of roots of Vetiveria zizanioïdes (VZ) was screened for gastroprotective activity by using Aspirin + pylorus ligation induced peptic ulcers in rats in which ulcer index, gastric wall mucus, antioxidant enzyme level like SOD, GSH, Catalase, & LPO in stomach were determined. It was found that animals belonging to VZ group reduced the ulcer index, increased mucus content as well as restored the antioxidant parameters in stomach and increased PH of gastric juice, decreased gastric volume and total acidity significantly as compared to ulcerated group of animals.

Further indications (including other extraction modes where applicable), dosages, precautions for use, and the <strong>full scientific references</strong> (complete records, not only the short excerpts above) are available in the complete monographic record in the Lapo v2 application.