Voacanga africana (Voacanga) : medicinal properties in alcoholic extraction

Voacanga africana (Voacanga) — family Apocynacées.

Scientific synonyms : Voacanga africana var glabra-(KS), V angolensis-S ex H, V klainei-P ex S, V glaberrima-W, V magnifolia-W, V puberula-KS, V scweinfurthii -S, V talbotii-W.

This database documents alcoholic (ethanol) extractions of active substances. Our monograph currently lists 6 indications in alcoholic extraction for this species. The Lapo v2 catalogue records 49 scientific references for this species (full detail in the application).

Important — scientific references on this public page: only a short excerpt of each cited source is shown (selected abstract sentences), kept in the original language of the publication (most often English), without translation. These excerpts are not the full article text and are not a complete bibliography. The full reference records and complete monographic detail are available in the Lapo v2 application (free 30-day trial).

1. 1

   Bacterial infection: Staphylococcus aureus, Klebsiella pneumoniae, Escherichia coli

   Plant part used: Fruit.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to Ndouguet Cliton (2021)

     Excerpt The polyphenols & flavonoids content of the crude extracts & the fractions have been determined by colorimetric methods & the antibacterial activity by the macro-dilution using Staphylococcus aureus, Klebsiella pneumoniae & Escherichia coli strains. The objective of this study was to carry out a comparative of the antibacterial activity of flavonoids of crude extracts & fractions of the fruit of Voacanga africana & Tabernaemontana contorta on the germs responsible for diarrhea.

   • According to Duru CM (2010)

     Excerpt The crude extracts exhibited antimicrobial activity against Escherichia coli (34.61 & 25%), Serratia marcescens (45.08 & 29.16%) & Staphylococcus aureus (42.10 & 34.21%). Dried & pulverized seeds of Voacanga africana were extracted with hot & cold absolute ethanol.

   • According to Ding CF (2018)

     Excerpt Both compounds exhibited potent activity against Staphylococcus aureus & Salmonella typhi, & their activities were superior to those of the well-known antibacterial drugs berberine & fibrauretine. Voacafricine A & B, two unique monoterpenoid indole alkaloids each bearing five fused heterocycles, were obtained from the fruits of Voacanga africana.

   • According to Maduaburi-DUCHU C (2010)

     Excerpt The crude extracts exhibited antimicrobial activity against Escherichia coli (34.61 & 25%), Serratia marcescens (45.08 & 29.16%) & Staphylococcus aureus (42.10 & 34.21%). Dried & pulverized seeds of Voacanga africana were extracted with hot & cold absolute ethanol.

2. 2

   Fungal infection: Alternaria solani, Aspergillus flavus, Candida albicans, Rhizopus stolonifer

   Plant part used: Seed.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to Duru CM (2010)

     Excerpt niger (25 & 00%) Candida albicans (29.62 & 25.92 %) & Rhizopus stolonifer (22.58 & 19.35 %); relative to the standard antibiotics, Gentamicin & Clotrimazole; in the Agar Well. Others are Alternaria solani (33.33 & 25%), Aspergillus flavus (33.33 & 22%), A.

   • According to Maduaburi-DUCHU C (2010)

     Excerpt niger (25 & 00%) Candida albicans (29.62 and 25.92 %) & Rhizopus stolonifer (22.58 and 19.35 %); relative to the standard antibiotics, Gentamicin & Clotrimazole; in the Agar Well. Others are Alternaria solani (33.33 & 25%), Aspergillus flavus (33.33 & 22%), A.

3. 3

   Memory disorder: adjunctive treatment for Alzheimer’s disease

   Plant part used: Fruit.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to Currais A (2014)

     Excerpt The goal of this study was to determine whether a phenotypic, cell-based screening approach can be applied to selected plants from STP (Voacanga africana, Tarenna nitiduloides, Sacosperma paniculatum, Psychotria principensis, Psychotria subobliqua) in order to identify natural compounds with multiple biological activities of interest for AD therapeutics. Results: An extract from the bark of Voacanga africana was more protective than any other plant extract in all of the assays (EC50sr2.4 mg/mL).

Further indications (including other extraction modes where applicable), dosages, precautions for use, and the <strong>full scientific references</strong> (complete records, not only the short excerpts above) are available in the complete monographic record in the Lapo v2 application.