Xanthium strumarium (Zédjoui-kochon) : medicinal properties in alcoholic extraction

Xanthium strumarium (Zédjoui-kochon, Pig’s needle, Lampourde, Aiguille-à-cochon) — family Astéracées.

Scientific synonyms : Xanthium canadense Mill, X. chinense Mill., X. glabratum, X. orientale L, X. pennsylvanicum Gand, X. sibiricum P. ex-W.

Recognised external sources linked to this monograph: TRAMIL.

This database documents alcoholic (ethanol) extractions of active substances. Our monograph currently lists 17 indications in alcoholic extraction for this species. The Lapo v2 catalogue records 71 scientific references for this species (full detail in the application).

Important — scientific references on this public page: only a short excerpt of each cited source is shown (selected abstract sentences), kept in the original language of the publication (most often English), without translation. These excerpts are not the full article text and are not a complete bibliography. The full reference records and complete monographic detail are available in the Lapo v2 application (free 30-day trial).

1. 1

   Cancer: adjuvant treatment for ascites carcinoma

   Plant part used: Root.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to Sridharamurthy NB (2011)

     Excerpt A mixture of Xanthine, Xanthone & Xanthosine isolated from the root of Xanthium strumarium exhibited antitumor activities against Ehrlich Ascites Carcinoma in Swiss albino mice. strumarium lignans in tumor bearing mice.

   • According to Sahebi-Asghar R (2014)

     Excerpt This study was exerted to determine the effects of Xanthium strumarium extract on viability of L929 cell lines. The studies indicate that there is association between herbal extracts & cancer treatment.

   • According to Tao L (2016)

     Excerpt We examined the effects of xanthatin on signaling pathways in A459 lung cancer cells & mouse embryonic fibroblasts to ascertain requirements for xanthatin-induced cell death & tumor growth in xenografts. Xanthatin, a xanthanolide sesquiterpene lactone isolated from Xanthium strumariumL.

   • According to Ramırez-Erosa Y (2007)

     Excerpt Ramırez-Erosa Y et al, Xanthatin & xanthinosin from the burs of Xanthium strumarium L. as potential anticancer agents, Canadian J of Physiol & Pharmacol, 85(11) :1160-72, 2007.

   • According to Aranjani JM (2013)

     Excerpt Preliminary evaluation of in vitro cytotoxicity & in vivo antitumor activity of Xanthium strumarium in transplantable tumors in mice.

2. 2

   Bacterial infection: Bacillus subtilis, Escherichia coli, Klebsiella pneumoniae, Klebsiella pneumoniae, Pseudomonas aeruginosa, Staphylococcus aureus

   Plant part used: Root.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to SRIDHARAMURTHY NB (2010)

     Excerpt The main objective of this study is to evaluate the antibacterial & antioxidant activity of ethanol extract of Xanthium strumarium Disc diffusion & broth serial dilution tests were used to determine the antibacterial activity of the ethanol extract on two Gram-positive strains (Bacillus subtilis NCIM 2718, Staphylococcus aureus ATCC25923) and three Gram-negative bacterial strains (Pseudomonas aeruginosa ATCC 27853, Klebsiella pneumoniae ATCC 70063 and Escherichia coli ATCC 25922).

   • According to CHANDEL (2012)

     Excerpt The present work was undertaken to evaluate the antiplasmodial activity of ethanolic leaves extract of traditional medicinal plant Xanthium strumarium in Plasmodium berghei-infected BALB/c mice along with phytochemical screening and acute toxicity test to support its traditional medicinal use as a malaria remedy. strumarium (ELEXS) 150, 250, 350 and 500 mg/kg/day demonstrated dose-dependent chemosuppression during early and established infection long with significant (p < 0.001) repository activity.

   • According to STUART BP (1981)

     Excerpt strumarium & Authentic carboxyatractyloside, when fed to pigs, caused signs and lesions typical of Cocklebur intoxication. Cocklebur (Xanthium strumarium) fed to feeder pigs was associated with acute to subacute hepato-toxicosis.

   • According to SHARMA SR (2003)

     Excerpt Anthelmintic activity of the fresh juice of Xanthium strumarium leaves at different concentration was evaluated in vitro, against Benzimidazole resistant Haemonchus contortus strain, using egg hatch assay (EHA) & larval paralysis test (LPT). No anthelmintic activity of the X strumarium juice was observed at 1: 100 dilutions, however, undiluted juice of the leaves showed a 100% inhibition in egg hatching by EHA.

   • According to Gharia A. K (2002)

     Excerpt Here Anthelmintic activity of essential oils of Bothriocloa pertusa, Abutilon indicum, Xanthium strumarium, Mentha spicata, Cinnamomum Zeylanicum, Santalum album, Parthenium hysterophorus were studied on earth worm, tape worm, hook worm and nodular worm and it was observed that essential oils from Xanthium strumarium possess superior anthelmintic activity against earth worm, tape worm, hook worm and nodular worm, as compared to standard substance.

3. 3

   High blood pressure, fluid retention, oedema, heavy legs

   Plant part used: Root.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to Patil MKV (2012)

     Excerpt Xanthium strumarium Linn. Theses extracts were tested against Carrageenan-induced paw edema and Freund's complete adjuvant (FCA) induced arthritic models in Wistar rats.

   • According to KIM IT (2005)

     Excerpt Methanol extract of Xanthium strumarium L. possesses anti-inflammatory & antinociceptive activities.

   • According to HAN T (2007)

     Excerpt Bioactivity-guided fractionation for antiinflammatory & analgesic properties & constituents of Xanthium strumarium L.

   • According to Kandhare AD (2012)

     Excerpt In view of antiinflammatory and antioxidant activity of Xanthium strumarium, the present investigation was designed to unravel its antiulcer potential in pylorus ligation induced gastric ulcer in Laboratory animals. The possible mechanism by which Xanthium strumarium exerts its gastroprotective action may be due to free radical quenching, DNA repair & down regulation of oxidative-nitrosative stress along with cytokines.

   • According to GUEMMAZ (2018)

     Excerpt the present study was undertaken to evaluate the in vitro & in vivo antioxidant effects of different extracts prepared from the leaves of Xanthium strumarium. However, the anti-hemolytic test demonstrated that the ChE was the most effective in protecting red blood cells, followed by the EAE, AqE & the CrE.

Further indications (including other extraction modes where applicable), dosages, precautions for use, and the <strong>full scientific references</strong> (complete records, not only the short excerpts above) are available in the complete monographic record in the Lapo v2 application.