Youngia japonica (Ti-Magrit-jôn-savann) : medicinal properties in alcoholic extraction

Youngia japonica (Ti-Magrit-jôn-savann, little yellow savannah daisy, petite marguerite-jaune-à-savane, pequeña margarita amarilla de la sabana) — family Asteracées.

Scientific synonyms : Youngia japonica subsp. longiflora.

This database documents alcoholic (ethanol) extractions of active substances. Our monograph currently lists 3 indications in alcoholic extraction for this species. The Lapo v2 catalogue records 16 scientific references for this species (full detail in the application).

Important — scientific references on this public page: only a short excerpt of each cited source is shown (selected abstract sentences), kept in the original language of the publication (most often English), without translation. These excerpts are not the full article text and are not a complete bibliography. The full reference records and complete monographic detail are available in the Lapo v2 application (free 30-day trial).

1. 1

   Cancer: adjuvant treatment of sarcoma, and of chronic and promyelocytic leukaemia

   Plant part used: Whole plant.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to MO Liya et al (n.d.)

     Excerpt The methanol extract of Youngia japonica was separated by column chromatography techniques （silica gel， ODS， Sephadex LH?20） & preparative HPLC. Hoechst33342/PI staining results showed that grosheimin could induce the apoptosis of two kinds of cancer cells in a concentration dependent manner & the apoptosis rates of MDA-MB-231 & HCT?116 were 45% & 37.78% respectively by flow cytometry under 20 μmol/L grosheimin treatment of 24 h.

   • According to Lee W.B et al (n.d.)

     Excerpt A new cytotoxic triterpene hydroperoxide (3) was isolated from the methylene chloride extract of the aerial part of Youngia japonica together with four known triterpenes (1, 2, 4 & 5). Compounds 3 & 5 showed moderate cytotoxicity against five tumor cell lines.

   • According to OOI LS et al (n.d.)

     Excerpt Aqueous & ethanol extracts of Youngia japonica (also known as Oriental hawksbeard) were tested in vitro for anti-tumor activity against three cell lines, human promyelocytic leukaemia (HL-60), human myelogenous leukaemia (chronic K-562) & mouse Sarcoma 180 (S-180), & for antiviral activity against respiratory syncytial virus (RSV), influenza A virus (Flu A) & herpes simplex virus type 1 (HSV-1) by cytopathic effect (CPE) reduction assay. The ethanol extract of whole plant of Youngia japonica exhibited antiviral activity against RSV cultured in HEp-2 cells, but did not have any activity against Flu A & HSV-1.

   • According to Ooi LS et al (n.d.)

     Excerpt Aqueous & ethanol extracts of Youngia Japonica (also known as Oriental hawksbeard) were tested in vitro for antitumor activity against three cell lines, human promyelocytic leukaemia (HL-60), human myelogenous leukaemia (chronic K-562) & mouse Sarcoma 180 (S-180), & for antiviral activity against respiratory syncytial virus (RSV), influenza A virus (Flu A) & herpès simplex virus type 1 (HSV-1) by cytopathic effect (CPE) reduction assay. The ethanol extract of whole plant of YJ exhibited antiviral activity against RSV cultured in HEp-2 cells, but did not have any activity against Flu A & HSV-1.

2. 2

   Viral infection caused by: RSV (Respiratory Syncytial Virus)

   Plant part used: Whole plant.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to OOI LS et al (n.d.)

     Excerpt Aqueous & ethanol extracts of Youngia japonica (also known as Oriental hawksbeard) were tested in vitro for anti-tumor activity against three cell lines, human promyelocytic leukaemia (HL-60), human myelogenous leukaemia (chronic K-562) & mouse Sarcoma 180 (S-180), & for antiviral activity against respiratory syncytial virus (RSV), influenza A virus (Flu A) & herpes simplex virus type 1 (HSV-1) by cytopathic effect (CPE) reduction assay. The ethanol extract of whole plant of Youngia japonica exhibited antiviral activity against RSV cultured in HEp-2 cells, but did not have any activity against Flu A & HSV-1.

   • According to Ooi LS et al (n.d.)

     Excerpt The ethanol extract of a biannual medicinal herb, Youngia Japonica (commonly known as Oriental hawk's Beard) was reported previously to have potent antiviral activity against respiratory syncytial virus (RSV) cultured in HEp-2 cells.

   • According to Ooi LS et al (n.d.)

     Excerpt Aqueous & ethanol extracts of Youngia Japonica (also known as Oriental hawksbeard) were tested in vitro for antitumor activity against three cell lines, human promyelocytic leukaemia (HL-60), human myelogenous leukaemia (chronic K-562) & mouse Sarcoma 180 (S-180), & for antiviral activity against respiratory syncytial virus (RSV), influenza A virus (Flu A) & herpès simplex virus type 1 (HSV-1) by cytopathic effect (CPE) reduction assay. The ethanol extract of whole plant of YJ exhibited antiviral activity against RSV cultured in HEp-2 cells, but did not have any activity against Flu A & HSV-1.

Further indications (including other extraction modes where applicable), dosages, precautions for use, and the <strong>full scientific references</strong> (complete records, not only the short excerpts above) are available in the complete monographic record in the Lapo v2 application.