Youngia japonica (Ti-Magrit-jôn-savann) : propiedades medicinales en extracción alcohólica

Youngia japonica (Ti-Magrit-jôn-savann, pequeña margarita amarilla de la sabana, petite marguerite-jaune-à-savane, little yellow savannah daisy) — familia Asteracées.

Sinónimos científicos : Youngia japonica subsp. longiflora.

Esta base documenta las extracciones alcohólicas (etanol) de las sustancias activas. Nuestra monografía recoge actualmente 3 indicaciones en extracción alcohólica para esta especie. El catálogo Lapo v2 registra 16 referencias científicas para esta especie (detalle completo en la aplicación).

Indicaciones terapéuticas en extracción alcohólica:

Importante — referencias científicas en esta página pública: solo se muestra un breve extracto de cada fuente citada (frases de resumen seleccionadas), conservado en el idioma original de la publicación (casi siempre el inglés), sin traducir. Estos extractos no constituyen el texto íntegro del artículo ni una bibliografía completa. Las fichas de referencia completas y el detalle monográfico están disponibles en la aplicación Lapo v2 (prueba gratuita de 30 días).

1. 1

   Cáncer: tratamiento adyuvante del sarcoma, así como de la leucemia crónica y la leucemia promielocítica

   Parte usada: Planta entera.

   Références scientifiques (courts extraits)

   Courts extraits uniquement (pas le texte intégral de l’article). Fiches de référence complètes dans l’application Lapo v2.

   • Selon MO Liya et al (s.d.)

     Extrait The methanol extract of Youngia japonica was separated by column chromatography techniques （silica gel， ODS， Sephadex LH?20） & preparative HPLC. Hoechst33342/PI staining results showed that grosheimin could induce the apoptosis of two kinds of cancer cells in a concentration dependent manner & the apoptosis rates of MDA-MB-231 & HCT?116 were 45% & 37.78% respectively by flow cytometry under 20 μmol/L grosheimin treatment of 24 h.

   • Selon Lee W.B et al (s.d.)

     Extrait A new cytotoxic triterpene hydroperoxide (3) was isolated from the methylene chloride extract of the aerial part of Youngia japonica together with four known triterpenes (1, 2, 4 & 5). Compounds 3 & 5 showed moderate cytotoxicity against five tumor cell lines.

   • Selon OOI LS et al (s.d.)

     Extrait Aqueous & ethanol extracts of Youngia japonica (also known as Oriental hawksbeard) were tested in vitro for anti-tumor activity against three cell lines, human promyelocytic leukaemia (HL-60), human myelogenous leukaemia (chronic K-562) & mouse Sarcoma 180 (S-180), & for antiviral activity against respiratory syncytial virus (RSV), influenza A virus (Flu A) & herpes simplex virus type 1 (HSV-1) by cytopathic effect (CPE) reduction assay. Hot water extract of Youngia japonica inhibited cell proliferation & growth of all cancer cell lines to various extent.

   • Selon Ooi LS et al (s.d.)

     Extrait Aqueous & ethanol extracts of Youngia Japonica (also known as Oriental hawksbeard) were tested in vitro for antitumor activity against three cell lines, human promyelocytic leukaemia (HL-60), human myelogenous leukaemia (chronic K-562) & mouse Sarcoma 180 (S-180), & for antiviral activity against respiratory syncytial virus (RSV), influenza A virus (Flu A) & herpès simplex virus type 1 (HSV-1) by cytopathic effect (CPE) reduction assay. Hot water extract of YJ inhibited cell proliferation & growth of all cancer cell lines to various extent.

2. 2

   Infección viral por: VSR (virus sincitial respiratorio)

   Parte usada: Planta entera.

   Références scientifiques (courts extraits)

   Courts extraits uniquement (pas le texte intégral de l’article). Fiches de référence complètes dans l’application Lapo v2.

   • Selon OOI LS et al (s.d.)

     Extrait Aqueous & ethanol extracts of Youngia japonica (also known as Oriental hawksbeard) were tested in vitro for anti-tumor activity against three cell lines, human promyelocytic leukaemia (HL-60), human myelogenous leukaemia (chronic K-562) & mouse Sarcoma 180 (S-180), & for antiviral activity against respiratory syncytial virus (RSV), influenza A virus (Flu A) & herpes simplex virus type 1 (HSV-1) by cytopathic effect (CPE) reduction assay. The ethanol extract of whole plant of Youngia japonica exhibited antiviral activity against RSV cultured in HEp-2 cells, but did not have any activity against Flu A & HSV-1.

   • Selon Ooi LS et al (s.d.)

     Extrait The ethanol extract of a biannual medicinal herb, Youngia Japonica (commonly known as Oriental hawk's Beard) was reported previously to have potent antiviral activity against respiratory syncytial virus (RSV) cultured in HEp-2 cells.

   • Selon Ooi LS et al (s.d.)

     Extrait Aqueous & ethanol extracts of Youngia Japonica (also known as Oriental hawksbeard) were tested in vitro for antitumor activity against three cell lines, human promyelocytic leukaemia (HL-60), human myelogenous leukaemia (chronic K-562) & mouse Sarcoma 180 (S-180), & for antiviral activity against respiratory syncytial virus (RSV), influenza A virus (Flu A) & herpès simplex virus type 1 (HSV-1) by cytopathic effect (CPE) reduction assay. The ratio of the viral titer reduction in the absence (viral control) & presence of the maximal non-cytotoxic concentration (MNCC) of the Fr.10 & Fr.11 was both estimated to be 1 x 10(4) (RF, viral titer reduction factors), indicating that their anti-RSV activity was high enough to justify for further analysis.

Otras indicaciones (incluidos otros modos de extracción si procede), posologías, precauciones de uso y las <strong>referencias científicas completas</strong> (fichas íntegras, no solo los extractos cortos anteriores) están disponibles en la ficha monográfica de la aplicación Lapo v2.