Alocasia macrorrhiza (Malanga mawon) : vertus médicinales en extraction alcoolique
Alocasia macrorrhiza (Malanga mawon, Chou mawon, Malanga marron, Chou marron, White taro, White cabbage, Brown taro, Brown cabbage) — famille Aracées.
Synonymes scientifiques : Arum indicum Lour., A macrorrhizon L., A macrorrhizum L., Caladium plumbeum K. Koch, Colocasia indica var. rubra Hassk., C indica (Lour.) Hassk., C macrorrhizos (L.) Schott, Alocasia indica var. metallica Schott ex Engl., A indica var. violacea Engl., A indica (Lour.) -Spach, Alocasia macrorrhizos var. rubra (Hassk.) Furtado, A macrorrhizos (L.) Schott, A metallica Schott.
Cette base documente les extractions alcooliques (éthanol) des substances actives. Notre monographie recense actuellement 22 indications en extraction alcoolique pour cette espèce. Le catalogue Lapo v2 enregistre 72 références scientifiques pour cette espèce (détail intégral dans l’application).
Indications thérapeutiques en extraction alcoolique :
Important — références scientifiques sur cette page publique : seuls de courts extraits de chaque source citée sont présentés (phrases d’abstract sélectionnées), conservés dans leur langue d’origine (le plus souvent l’anglais), sans traduction. Ces extraits ne constituent pas le texte intégral de l’article ni une bibliographie complète. Les fiches de référence complètes et le détail monographique sont disponibles dans l’application Lapo v2 (essai gratuit 30 jours).
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Cancer : traitement adjuvant du carcinome : épithélial nasopharyngé, oropharyngé (gorge), et hépatique
Références scientifiques (courts extraits)
Courts extraits uniquement (pas le texte intégral de l’article). Fiches de référence complètes dans l’application Lapo v2.
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Selon Arbain D (2022)
Extrait The numerous biological activities of Alocasia species were also presented, which include anti-cancer, antidiabetic & antihyperglycaemic, antioxidant, antidiarrhoeal, antimicrobial & antifungal, antiparasitic (antiprotozoal & anthelminthic), antinociceptive & anti-inflammatory, brine shrimp lethality, hepatoprotective, anti-hemagglutinin, anti-constipation & diuretic, & radioprotective activities as well as acute toxicity studies. The genus Alocasia was reported to be able to produce a strong & high-quality anti-cancer compound, namely alocasgenoside B, although information on this compound is currently limited.
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Selon Fang S (2012)
Extrait Fang S et al, Anticancer potential of aqueous extract of alocasia macrorrhiza against hepatic cancer in vitro & in vivo.
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Selon -Pal S (s.d.)
Extrait indica tuber (EEAIT) in hepatotoxicity and apoptosis of liver caused by alcohol in rats was investigated. Treatment of rats with alcohol (3 g ethanol per kg body weight per day for 15 days intraperitoneally) produced marked elevation of liver biomarkers such as serum alanine aminotransferase (ALT), aspartate aminotransferase (AST), -glutamyl transpeptidase (-GT), & total bilirubin levels which were reduced by EEAIT in a dose-dependent manner.
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Selon Mulla WA (s.d.)
Extrait Hepatic steatosis, fatty infiltration, hydropic degeneration & necrosis observed in CCl4 & paracetamol-treated groups were completely absent in histology of the liver sections of the animals treated with the extracts. The results suggests that the hydroalcoholic extract of leaves of AI possess significant potential as hepatoprotective agent.
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Selon Pal S (s.d.)
Extrait In-vitro analyses such as phenolic & flavonoid contents, antioxidant activity were done using standard spectrophotometric method & in-vivo antioxidant activity was evaluated by using carbon tetrachloride induced hepatic injuries in male Albino Wister rats. indica tuber were prepared to evaluate in-vitro antioxidant potential, in-vivo hepatoprotective activity & GCMS analysis of the extract.
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Selon Arbain D (2022)
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Diabète mellitus de type II
Références scientifiques (courts extraits)
Courts extraits uniquement (pas le texte intégral de l’article). Fiches de référence complètes dans l’application Lapo v2.
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Selon RAHMAN M (2012)
Extrait The extract was given at a single dose (250 & 500 mg/kg) in alloxan-induced hyperglycemic mice. Alocasia macrorrhizos (L.) (Araceae), a coarse & erect plant that is widely cultivated to be eaten as a vegetable throughout Bangladesh, has been reported to possess a number of medicinal properties.
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Selon Jawaid T (2015)
Extrait The investigate the antidiabetic & antihyperlipidemic effect of ethanolic extract of Alocasia indica (EEAI) rhizomes in high-fat diet/streptozotocin (HFD/STZ) & STZ/nicotinamide-induced Type 2 diabetic rats. Conclusion: The results suggest that the EEAI rhizomes possess a promising effect on the HFD/STZ & STZ/nicotinamide-induced Type 2 diabetes.
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Selon Yuliana Y (2018)
Extrait From the root part, aloceramide compounds have been isolated, whereas rhizome containing lignanamide, monoindole, indole & piperidin compounds & leaves have triglochinin & isotriglochinin components. Furthermore, the plant also has biological activities such as antidiuretic, anticancer, antioxidant, antimicrobial, antidiabetic, antihyperglycemia & others.
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Selon Karim R (2014)
Extrait The present study was aimed at evaluating the effect of Alocasia indica on blood glucose level in normal & Streptozotocin-induced diabetic rats with stress on evaluation of probable mechanism of antidiabetic action. Diabetes was induced by single intraperitoneal injection of Streptozotocin (60 mg/kg) and doses of test extracts 200 and 400mg/kg were studied in Streptozotocin induced diabetic rats for the period of 21 days.
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Selon Arbain D (2022)
Extrait The numerous biological activities of Alocasia species were also presented, which include anti-cancer, antidiabetic & antihyperglycaemic, antioxidant, antidiarrhoeal, antimicrobial & antifungal, antiparasitic (antiprotozoal & anthelminthic), antinociceptive & anti-inflammatory, brine shrimp lethality, hepatoprotective, anti-hemagglutinin, anti-constipation & diuretic, & radioprotective activities as well as acute toxicity studies. Featuring their large green heart-shaped or arrow-shaped ear leaves & occasionally red-orange fruit, they are very popular ornamental plants & are widely used as traditional medicines to treat various diseases such as jaundice, snake bite, boils, & diabetes.
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Selon RAHMAN M (2012)
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Hépatopathies: normalisation des paramètres sériques : ALT, AST, etc
Références scientifiques (courts extraits)
Courts extraits uniquement (pas le texte intégral de l’article). Fiches de référence complètes dans l’application Lapo v2.
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Selon -Pal S (s.d.)
Extrait Treatment of rats with alcohol (3 g ethanol per kg body weight per day for 15 days intraperitoneally) produced marked elevation of liver biomarkers such as serum alanine aminotransferase (ALT), aspartate aminotransferase (AST), -glutamyl transpeptidase (-GT), & total bilirubin levels which were reduced by EEAIT in a dose-dependent manner. indica tuber (EEAIT) in hepatotoxicity and apoptosis of liver caused by alcohol in rats was investigated.
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Selon Mulla WA (s.d.)
Extrait Hepatic steatosis, fatty infiltration, hydropic degeneration & necrosis observed in CCl4 & paracetamol-treated groups were completely absent in histology of the liver sections of the animals treated with the extracts. indica (250 & 500 mg/kg) effectively inhibited CCl4 & paracetamol induced changes in the serum marker enzymes, cholesterol, serum protein & albumin in a dose-dependent manner as compared to the normal & the standard drug silymarin-treated groups.
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Selon Pal S (s.d.)
Extrait In-vitro analyses such as phenolic & flavonoid contents, antioxidant activity were done using standard spectrophotometric method & in-vivo antioxidant activity was evaluated by using carbon tetrachloride induced hepatic injuries in male Albino Wister rats. indica tuber were prepared to evaluate in-vitro antioxidant potential, in-vivo hepatoprotective activity & GCMS analysis of the extract.
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Selon ACHARYA S (2014)
Extrait Alocasia macrorrhizos (AM) belongs to the family Araceae, different parts of this plant have shown hepatoprotective, anti-oxidant & anti-inflammatory action.
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Selon Basu S (2014)
Extrait To assess the complete nutritional profile and identification of bioactive components present in the hydro-ethanolic extract of Alocasia indica tuber.
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Selon -Pal S (s.d.)
D’autres indications (y compris d’autres modes d’extraction le cas échéant), posologies, précautions d’emploi et les <strong>références scientifiques complètes</strong> (fiches intégrales, pas seulement les courts extraits ci-dessus) sont disponibles dans la fiche monographique de l’application Lapo v2.
Évolution de cette fiche publique
Sous le CTA · journal des mises à jour
+11 références · −11 références
Compteurs et domaines uniquement : les libellés d’indications et les noms de synergies ne sont pas publiés ici (ouvrir la fiche dans l’application). Les textes complets des références ajoutées, corrigées ou retirées sont ci-dessous.
+11 références — afficher les textes
Ongpoy RC., Jr, The Medicinal Properties of the Alocasia Genus: A Systematic Review. JAASP 6 (1), 25–33. 2017-Abstract: The objective of this study is to evaluate the existing medicinal studies of the Alocasia genus & identify the possible studies that may be done in the future on its member species. To do this, Science Direct & Google Scholar were used as a database to get the available researches searching for the term “Alocasia” & some of its common species like “Alocasia macrorrhiza”. Fifty eight articles were selected & from these, 28 were qualified for this systematic review. Results …
AjoutéeMulla WA et al, Free Radical Scavenging Activity of Leaves of Alocasia Indica (Linn). Indian J. Pharm. Sci. 71 (3), 303–7. 10.4103/0250-474X.56036, 2009b-Abstract: The free radical scavenging potential of the plant Alocasia indica(Linn.) was studied by using different antioxidant models of screening like scavenging of 1,1-diphenyl-2-picryl hydrazyl radical, nitric oxide radical, superoxide anion radical, hydroxyl radical, iron chelating activity, total antioxidant capacity, non-enzymatic glycosylation of haemoglobin, rapid screening for antioxidant compounds by thin layer chromatography. Th…
AjoutéeMulla WA et al, Anthelmintic Activity of Leaves of Alocasia Indica Linn. Int. J. Pharmtech Res. 2 (1):26–30. 10.4103/0975-1483.63152,2010b-Abstract : The study was designed to evaluate the anthelmintic activity of hydroalcoholic extract of leaves of Alocasia indica Linn.(Araceae) & its two different fractions namely petroleum ether & ethyl acetate using Pheretima posthuma as test worms. Different concentrations (10, 25 and 50 mg/ml) of hydroalcoholic extract and its various fractions were tested in the bioassay, from which time of paralysis (P) & time of death (D) of the worms were determin…
AjoutéeBuyel JF. How Plants Can Contribute to the Supply of Anticancer Compounds,” in Biotechnology & Production of Anti-cancer Compounds. Editor Malik S. (Cham: Springer Inter Publishing; ), 39–72. 2017- [
AjoutéeHuang W et al, Piperidine Alkaloids from Alocasia macrorrhiza . Phytochem, 143, 81–6. 2017b-Abstract :Six previously undescribed piperidine alkaloids were isolated from the rhizomes of Alocasia macrorrhiza (L.) Schott. Their structures were elucidated based on 1D & 2D NMR, IR, HR-ESI-MS spectroscopic analysis & the application of a modified Mosher method. All isolated alkaloids were evaluated for cytotoxicity against five human cancer cell lines (CNE-1, Detroit 562, Fadu, MGC-803, & MCF-7) using the MTT method. Only one compound exhibited cytotoxic effects against Detroit 562, Fadu, & MCF-7…
AjoutéeMulla WA et al, Hepatoprotective Activity of Hydroalcoholic Extract of Leaves of Alocasia Indica (Linn.). Indian J. Exp. Biol. 47 (10):816–21.2009a-Abstract: Oral administration of hydroalcoholic extract of A. indica (250 & 500 mg/kg) effectively inhibited CCl4 & paracetamol induced changes in the serum marker enzymes, cholesterol, serum protein & albumin in a dose-dependent manner as compared to the normal & the standard drug silymarin-treated groups. Hepatic steatosis, fatty infiltration, hydropic degeneration & necrosis observed in CCl4 & paracetamol-treated groups were completely absent…
AjoutéeHuang W et al, Anti-inflammatory Lignanamides & Monoindoles from Alocasia macrorrhiza . Fitoterapia 117, 126–32. 2017a-Abstract: Five new lignanamides (1-5), and one new monoindole alkaloid (6), along with eight known compounds (7-14) were isolated & identified from the rhizomes of Alocasia macrorrhiza (giant taro). All purified compounds were evaluated for their inhibitory effects on lipopolysaccharide (LPS)-induced nitric oxide (NO) production in RAW 264.7 cells, & the antiproliferative activities against human nasopharyngeal carcinoma epithelial (CNE-1), human gastric carcinoma (MGC-803)…
AjoutéeLin TJ et al, Calcium oxalate is the main toxic component in clinical presentations of alocasis macrorrhiza (L) Schott & Endl poisonings Vet Hum Toxicol. 1998, 40(2) 93-5-Abstract : The toxic effects of A macrorrhiza arise from sapotoxin & include gastroenteritis & paralysis of the nerve centers. From 1985 to 1993 all individuals who called the Poison Control Center asking for information regarding macrorrhiza were included in this retrospective study. A questionnaire filled out by the Poison Control Center staff collected the demographic data of the victim, the reason for consumption, the…
AjoutéeLin TJ et al, Calcium oxalate is the main toxic component in clinical presentations of Alocasis macrorrhiza (L) Schot & Endl poisonings. Vet Hum Toxicol 1998;40:93-5.
AjoutéeZhu LH et al, Study on Chemical Constituents of Alocasia macrorrhiza (L.) Schott Chinese Pharmaceut J, 2012-13-Abstract
AjoutéeZhu LH et al, Indole Alkaloids from Alocasia macrorrhiza . Chem. Pharm. Bull. (Tokyo) 60 (5), 670–3. 10.1248/cpb.60.670, 2012-Abstract : Five new indole alkaloids, alocasins A–E (3–7), together with known hyrtiosin B (1) & hyrtiosulawe- sin (2) were isolated from Alocasia macrorrhiza (L.) SCHOTT; their structures were elucidated on the basis of spectroscopic data. Compounds 1–7 were in vitro tested for cytostatic activity on human throat cancer (Hep- 2), human hepatocarcinoma (Hep-G2), & human nasopharyngeal carcinoma epithelial (CNE) cell lines by 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenylt…
AjoutéeBuyel JF. How Plants Can Contribute to the Supply of Anticancer Compounds,” in Biotechnology & Production of Anti-cancer Compounds. Editor Malik S. (Cham: Springer Inter Publishing; ), 39–72. 2017- [
RetiréeHuang W et al, Piperidine Alkaloids from Alocasia macrorrhiza . Phytochem, 143, 81–6. 2017b-Abstract :Six previously undescribed piperidine alkaloids were isolated from the rhizomes of Alocasia macrorrhiza (L.) Schott. Their structures were elucidated based on 1D & 2D NMR, IR, HR-ESI-MS spectroscopic analysis & the application of a modified Mosher method. All isolated alkaloids were evaluated for cytotoxicity against five human cancer cell lines (CNE-1, Detroit 562, Fadu, MGC-803, & MCF-7) using the MTT method. Only one compound exhibited cytotoxic effects against Detroit 562, Fadu, & MCF-7…
RetiréeMulla WA et al, Hepatoprotective Activity of Hydroalcoholic Extract of Leaves of Alocasia Indica (Linn.). Indian J. Exp. Biol. 47 (10):816–21.2009a-Abstract: Oral administration of hydroalcoholic extract of A. indica (250 & 500 mg/kg) effectively inhibited CCl4 & paracetamol induced changes in the serum marker enzymes, cholesterol, serum protein & albumin in a dose-dependent manner as compared to the normal & the standard drug silymarin-treated groups. Hepatic steatosis, fatty infiltration, hydropic degeneration & necrosis observed in CCl4 & paracetamol-treated groups were completely absent…
RetiréeHuang W et al, Anti-inflammatory Lignanamides & Monoindoles from Alocasia macrorrhiza . Fitoterapia 117, 126–32. 2017a-Abstract: Five new lignanamides (1-5), and one new monoindole alkaloid (6), along with eight known compounds (7-14) were isolated & identified from the rhizomes of Alocasia macrorrhiza (giant taro). All purified compounds were evaluated for their inhibitory effects on lipopolysaccharide (LPS)-induced nitric oxide (NO) production in RAW 264.7 cells, & the antiproliferative activities against human nasopharyngeal carcinoma epithelial (CNE-1), human gastric carcinoma (MGC-803)…
RetiréeOngpoy RC., Jr, The Medicinal Properties of the Alocasia Genus: A Systematic Review. JAASP 6 (1), 25–33. 2017-Abstract: The objective of this study is to evaluate the existing medicinal studies of the Alocasia genus & identify the possible studies that may be done in the future on its member species. To do this, Science Direct & Google Scholar were used as a database to get the available researches searching for the term “Alocasia” & some of its common species like “Alocasia macrorrhiza”. Fifty eight articles were selected & from these, 28 were qualified for this systematic review. Results …
RetiréeMulla WA et al, Free Radical Scavenging Activity of Leaves of Alocasia Indica (Linn). Indian J. Pharm. Sci. 71 (3), 303–7. 10.4103/0250-474X.56036, 2009b-Abstract: The free radical scavenging potential of the plant Alocasia indica(Linn.) was studied by using different antioxidant models of screening like scavenging of 1,1-diphenyl-2-picryl hydrazyl radical, nitric oxide radical, superoxide anion radical, hydroxyl radical, iron chelating activity, total antioxidant capacity, non-enzymatic glycosylation of haemoglobin, rapid screening for antioxidant compounds by thin layer chromatography. Th…
RetiréeMulla WA et al, Anthelmintic Activity of Leaves of Alocasia Indica Linn. Int. J. Pharmtech Res. 2 (1):26–30. 10.4103/0975-1483.63152,2010b-Abstract : The study was designed to evaluate the anthelmintic activity of hydroalcoholic extract of leaves of Alocasia indica Linn.(Araceae) & its two different fractions namely petroleum ether & ethyl acetate using Pheretima posthuma as test worms. Different concentrations (10, 25 and 50 mg/ml) of hydroalcoholic extract and its various fractions were tested in the bioassay, from which time of paralysis (P) & time of death (D) of the worms were determin…
RetiréeLin TJ et al, Calcium oxalate is the main toxic component in clinical presentations of alocasis macrorrhiza (L) Schott & Endl poisonings Vet Hum Toxicol. 1998, 40(2) 93-5-Abstract : The toxic effects of A macrorrhiza arise from sapotoxin & include gastroenteritis & paralysis of the nerve centers. From 1985 to 1993 all individuals who called the Poison Control Center asking for information regarding macrorrhiza were included in this retrospective study. A questionnaire filled out by the Poison Control Center staff collected the demographic data of the victim, the reason for consumption, the…
RetiréeLin TJ et al, Calcium oxalate is the main toxic component in clinical presentations of Alocasis macrorrhiza (L) Schot & Endl poisonings. Vet Hum Toxicol 1998;40:93-5.
RetiréeZhu LH et al, Study on Chemical Constituents of Alocasia macrorrhiza (L.) Schott Chinese Pharmaceut J, 2012-13-Abstract
RetiréeZhu LH et al, Indole Alkaloids from Alocasia macrorrhiza . Chem. Pharm. Bull. (Tokyo) 60 (5), 670–3. 10.1248/cpb.60.670, 2012-Abstract : Five new indole alkaloids, alocasins A–E (3–7), together with known hyrtiosin B (1) & hyrtiosulawe- sin (2) were isolated from Alocasia macrorrhiza (L.) SCHOTT; their structures were elucidated on the basis of spectroscopic data. Compounds 1–7 were in vitro tested for cytostatic activity on human throat cancer (Hep- 2), human hepatocarcinoma (Hep-G2), & human nasopharyngeal carcinoma epithelial (CNE) cell lines by 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenylt…
RetiréePremière publication publique
+1 indication · −1 indication · ~ posologie · +11 références · −11 références
Compteurs et domaines uniquement : les libellés d’indications et les noms de synergies ne sont pas publiés ici (ouvrir la fiche dans l’application). Les textes complets des références ajoutées, corrigées ou retirées sont ci-dessous.
+11 références — afficher les textes
Buyel JF. How Plants Can Contribute to the Supply of Anticancer Compounds,” in Biotechnology & Production of Anti-cancer Compounds. Editor Malik S. (Cham: Springer Inter Publishing; ), 39–72. 2017- [
AjoutéeHuang W et al, Piperidine Alkaloids from Alocasia macrorrhiza . Phytochem, 143, 81–6. 2017b-Abstract :Six previously undescribed piperidine alkaloids were isolated from the rhizomes of Alocasia macrorrhiza (L.) Schott. Their structures were elucidated based on 1D & 2D NMR, IR, HR-ESI-MS spectroscopic analysis & the application of a modified Mosher method. All isolated alkaloids were evaluated for cytotoxicity against five human cancer cell lines (CNE-1, Detroit 562, Fadu, MGC-803, & MCF-7) using the MTT method. Only one compound exhibited cytotoxic effects against Detroit 562, Fadu, & MCF-7…
AjoutéeMulla WA et al, Hepatoprotective Activity of Hydroalcoholic Extract of Leaves of Alocasia Indica (Linn.). Indian J. Exp. Biol. 47 (10):816–21.2009a-Abstract: Oral administration of hydroalcoholic extract of A. indica (250 & 500 mg/kg) effectively inhibited CCl4 & paracetamol induced changes in the serum marker enzymes, cholesterol, serum protein & albumin in a dose-dependent manner as compared to the normal & the standard drug silymarin-treated groups. Hepatic steatosis, fatty infiltration, hydropic degeneration & necrosis observed in CCl4 & paracetamol-treated groups were completely absent…
AjoutéeHuang W et al, Anti-inflammatory Lignanamides & Monoindoles from Alocasia macrorrhiza . Fitoterapia 117, 126–32. 2017a-Abstract: Five new lignanamides (1-5), and one new monoindole alkaloid (6), along with eight known compounds (7-14) were isolated & identified from the rhizomes of Alocasia macrorrhiza (giant taro). All purified compounds were evaluated for their inhibitory effects on lipopolysaccharide (LPS)-induced nitric oxide (NO) production in RAW 264.7 cells, & the antiproliferative activities against human nasopharyngeal carcinoma epithelial (CNE-1), human gastric carcinoma (MGC-803)…
AjoutéeOngpoy RC., Jr, The Medicinal Properties of the Alocasia Genus: A Systematic Review. JAASP 6 (1), 25–33. 2017-Abstract: The objective of this study is to evaluate the existing medicinal studies of the Alocasia genus & identify the possible studies that may be done in the future on its member species. To do this, Science Direct & Google Scholar were used as a database to get the available researches searching for the term “Alocasia” & some of its common species like “Alocasia macrorrhiza”. Fifty eight articles were selected & from these, 28 were qualified for this systematic review. Results …
AjoutéeMulla WA et al, Free Radical Scavenging Activity of Leaves of Alocasia Indica (Linn). Indian J. Pharm. Sci. 71 (3), 303–7. 10.4103/0250-474X.56036, 2009b-Abstract: The free radical scavenging potential of the plant Alocasia indica(Linn.) was studied by using different antioxidant models of screening like scavenging of 1,1-diphenyl-2-picryl hydrazyl radical, nitric oxide radical, superoxide anion radical, hydroxyl radical, iron chelating activity, total antioxidant capacity, non-enzymatic glycosylation of haemoglobin, rapid screening for antioxidant compounds by thin layer chromatography. Th…
AjoutéeMulla WA et al, Anthelmintic Activity of Leaves of Alocasia Indica Linn. Int. J. Pharmtech Res. 2 (1):26–30. 10.4103/0975-1483.63152,2010b-Abstract : The study was designed to evaluate the anthelmintic activity of hydroalcoholic extract of leaves of Alocasia indica Linn.(Araceae) & its two different fractions namely petroleum ether & ethyl acetate using Pheretima posthuma as test worms. Different concentrations (10, 25 and 50 mg/ml) of hydroalcoholic extract and its various fractions were tested in the bioassay, from which time of paralysis (P) & time of death (D) of the worms were determin…
AjoutéeLin TJ et al, Calcium oxalate is the main toxic component in clinical presentations of alocasis macrorrhiza (L) Schott & Endl poisonings Vet Hum Toxicol. 1998, 40(2) 93-5-Abstract : The toxic effects of A macrorrhiza arise from sapotoxin & include gastroenteritis & paralysis of the nerve centers. From 1985 to 1993 all individuals who called the Poison Control Center asking for information regarding macrorrhiza were included in this retrospective study. A questionnaire filled out by the Poison Control Center staff collected the demographic data of the victim, the reason for consumption, the…
AjoutéeLin TJ et al, Calcium oxalate is the main toxic component in clinical presentations of Alocasis macrorrhiza (L) Schot & Endl poisonings. Vet Hum Toxicol 1998;40:93-5.
AjoutéeZhu LH et al, Study on Chemical Constituents of Alocasia macrorrhiza (L.) Schott Chinese Pharmaceut J, 2012-13-Abstract
AjoutéeZhu LH et al, Indole Alkaloids from Alocasia macrorrhiza . Chem. Pharm. Bull. (Tokyo) 60 (5), 670–3. 10.1248/cpb.60.670, 2012-Abstract : Five new indole alkaloids, alocasins A–E (3–7), together with known hyrtiosin B (1) & hyrtiosulawe- sin (2) were isolated from Alocasia macrorrhiza (L.) SCHOTT; their structures were elucidated on the basis of spectroscopic data. Compounds 1–7 were in vitro tested for cytostatic activity on human throat cancer (Hep- 2), human hepatocarcinoma (Hep-G2), & human nasopharyngeal carcinoma epithelial (CNE) cell lines by 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenylt…
AjoutéeBuyel JF. How Plants Can Contribute to the Supply of Anticancer Compounds,” in Biotechnology & Production of Anti-cancer Compounds. Editor Malik S. (Cham: Springer Inter Publishing; ), 39–72. 2017- [
RetiréeHuang W et al, Piperidine Alkaloids from Alocasia macrorrhiza . Phytochem, 143, 81–6. 2017b-Abstract :Six previously undescribed piperidine alkaloids were isolated from the rhizomes of Alocasia macrorrhiza (L.) Schott. Their structures were elucidated based on 1D & 2D NMR, IR, HR-ESI-MS spectroscopic analysis & the application of a modified Mosher method. All isolated alkaloids were evaluated for cytotoxicity against five human cancer cell lines (CNE-1, Detroit 562, Fadu, MGC-803, & MCF-7) using the MTT method. Only one compound exhibited cytotoxic effects against Detroit 562, Fadu, & MCF-7…
RetiréeMulla WA et al, Hepatoprotective Activity of Hydroalcoholic Extract of Leaves of Alocasia Indica (Linn.). Indian J. Exp. Biol. 47 (10):816–21.2009a-Abstract: Oral administration of hydroalcoholic extract of A. indica (250 & 500 mg/kg) effectively inhibited CCl4 & paracetamol induced changes in the serum marker enzymes, cholesterol, serum protein & albumin in a dose-dependent manner as compared to the normal & the standard drug silymarin-treated groups. Hepatic steatosis, fatty infiltration, hydropic degeneration & necrosis observed in CCl4 & paracetamol-treated groups were completely absent…
RetiréeHuang W et al, Anti-inflammatory Lignanamides & Monoindoles from Alocasia macrorrhiza . Fitoterapia 117, 126–32. 2017a-Abstract: Five new lignanamides (1-5), and one new monoindole alkaloid (6), along with eight known compounds (7-14) were isolated & identified from the rhizomes of Alocasia macrorrhiza (giant taro). All purified compounds were evaluated for their inhibitory effects on lipopolysaccharide (LPS)-induced nitric oxide (NO) production in RAW 264.7 cells, & the antiproliferative activities against human nasopharyngeal carcinoma epithelial (CNE-1), human gastric carcinoma (MGC-803)…
RetiréeOngpoy RC., Jr, The Medicinal Properties of the Alocasia Genus: A Systematic Review. JAASP 6 (1), 25–33. 2017-Abstract: The objective of this study is to evaluate the existing medicinal studies of the Alocasia genus & identify the possible studies that may be done in the future on its member species. To do this, Science Direct & Google Scholar were used as a database to get the available researches searching for the term “Alocasia” & some of its common species like “Alocasia macrorrhiza”. Fifty eight articles were selected & from these, 28 were qualified for this systematic review. Results …
RetiréeMulla WA et al, Free Radical Scavenging Activity of Leaves of Alocasia Indica (Linn). Indian J. Pharm. Sci. 71 (3), 303–7. 10.4103/0250-474X.56036, 2009b-Abstract: The free radical scavenging potential of the plant Alocasia indica(Linn.) was studied by using different antioxidant models of screening like scavenging of 1,1-diphenyl-2-picryl hydrazyl radical, nitric oxide radical, superoxide anion radical, hydroxyl radical, iron chelating activity, total antioxidant capacity, non-enzymatic glycosylation of haemoglobin, rapid screening for antioxidant compounds by thin layer chromatography. Th…
RetiréeMulla WA et al, Anthelmintic Activity of Leaves of Alocasia Indica Linn. Int. J. Pharmtech Res. 2 (1):26–30. 10.4103/0975-1483.63152,2010b-Abstract : The study was designed to evaluate the anthelmintic activity of hydroalcoholic extract of leaves of Alocasia indica Linn.(Araceae) & its two different fractions namely petroleum ether & ethyl acetate using Pheretima posthuma as test worms. Different concentrations (10, 25 and 50 mg/ml) of hydroalcoholic extract and its various fractions were tested in the bioassay, from which time of paralysis (P) & time of death (D) of the worms were determin…
RetiréeLin TJ et al, Calcium oxalate is the main toxic component in clinical presentations of alocasis macrorrhiza (L) Schott & Endl poisonings Vet Hum Toxicol. 1998, 40(2) 93-5-Abstract : The toxic effects of A macrorrhiza arise from sapotoxin & include gastroenteritis & paralysis of the nerve centers. From 1985 to 1993 all individuals who called the Poison Control Center asking for information regarding macrorrhiza were included in this retrospective study. A questionnaire filled out by the Poison Control Center staff collected the demographic data of the victim, the reason for consumption, the…
RetiréeLin TJ et al, Calcium oxalate is the main toxic component in clinical presentations of Alocasis macrorrhiza (L) Schot & Endl poisonings. Vet Hum Toxicol 1998;40:93-5.
RetiréeZhu LH et al, Study on Chemical Constituents of Alocasia macrorrhiza (L.) Schott Chinese Pharmaceut J, 2012-13-Abstract
RetiréeZhu LH et al, Indole Alkaloids from Alocasia macrorrhiza . Chem. Pharm. Bull. (Tokyo) 60 (5), 670–3. 10.1248/cpb.60.670, 2012-Abstract : Five new indole alkaloids, alocasins A–E (3–7), together with known hyrtiosin B (1) & hyrtiosulawe- sin (2) were isolated from Alocasia macrorrhiza (L.) SCHOTT; their structures were elucidated on the basis of spectroscopic data. Compounds 1–7 were in vitro tested for cytostatic activity on human throat cancer (Hep- 2), human hepatocarcinoma (Hep-G2), & human nasopharyngeal carcinoma epithelial (CNE) cell lines by 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenylt…
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