Argemone mexicana (Zèb-dragon) : vertus médicinales en extraction alcoolique
Argemone mexicana (Zèb-dragon, Herbe dragon, Dragon Grass) — famille Papavéracées.
Synonymes scientifiques : Argemone alba-Raf, A spinosa-Moench, A vulgaris-Spach, Papaver mexicana-(L)-EH Krause.
Sources externes reconnues associées à cette monographie : TRAMIL et Pharmacopée française.
Cette base documente les extractions alcooliques (éthanol) des substances actives. Notre monographie recense actuellement 20 indications en extraction alcoolique pour cette espèce. Le catalogue Lapo v2 enregistre 163 références scientifiques pour cette espèce (détail intégral dans l’application).
Indications thérapeutiques en extraction alcoolique :
Important — références scientifiques sur cette page publique : seuls de courts extraits de chaque source citée sont présentés (phrases d’abstract sélectionnées), conservés dans leur langue d’origine (le plus souvent l’anglais), sans traduction. Ces extraits ne constituent pas le texte intégral de l’article ni une bibliographie complète. Les fiches de référence complètes et le détail monographique sont disponibles dans l’application Lapo v2 (essai gratuit 30 jours).
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Diabète mellitus de type II
Références scientifiques (courts extraits)
Courts extraits uniquement (pas le texte intégral de l’article). Fiches de référence complètes dans l’application Lapo v2.
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Selon Nayak P (2011)
Extrait The present study was designed to investigate the possible actions of ethanolic & aqueous extract of aerial parts of A mexicana, on glucose homeostasis in acute normoglycemic & alloxan induced hyperglycemic rats, including oral glucose tolerance & up to 11-days of study in hyperglycaemic rats. It is concluded that, the extracts of the aerial parts of A mexicana, endowed with potent antidiabetic activity, which might be contributed by pancreatic & or extra pancreatic action of the test extracts.
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Selon Rout SP (2011)
Extrait Rout SP et al, Hypoglycaemic activity of aerial parts of Argemone mexicana L.
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Selon Nayak P (2011)
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Infection bacterienne Pseudomonas putida, Salmonella typhi, Vibrio cholera, Staphylococcus aureus, Pectobacterium corotavarum
Références scientifiques (courts extraits)
Courts extraits uniquement (pas le texte intégral de l’article). Fiches de référence complètes dans l’application Lapo v2.
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Selon Saravanan R (2017)
Extrait The present study was under taken to verify the effect of Argemone Mexicana roots & its stem on experimentally induced excision wound in the rats & antimicrobial activity against highly pathogenic organisms like Pseudomonas putida, Salmonella typhi, Vibrio cholera, Staphylococcus aureus, Pectobacterium coronaturum. The present study is to monitor the anti microbial activity & wound healing activity of ethanolic extracts of stem, root & other parts of the plant A mexicana belongs to the family Papaveraceae.
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Selon Singh S (2009)
Extrait Antibacterial activity of seed extracts of Argemone mexicana (Papaveraceae) was evaluated against some pathogenic bacterial strains. MIC values were 2.0 & 3.0 mg/ml, respectively, for Staphylococcus aureus & Pseudomonas aeruginosa and their respective drug-resistant strains.
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Selon Singh SK (s.d.)
Extrait Singh SK et al, Antibacterial activity of seed extracts of Argemone mexicana L.
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Selon Sahu MC (2012)
Extrait Sahu MC et al, Antibacterial activity of Argemone mexicana L. against multidrug resistant Pseudomonas aeruginosa, isolated from clinical samples.
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Selon Desai SS (2014)
Extrait Antimicrobial activity of plant extract against two bacterial strains (Bacillus subtilis & Escherichia coli) was performed by agar well diffusion method. The Argemone mexicana Linn.
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Selon Saravanan R (2017)
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Maladies auto-immunes : psoriasis, sclérodermie, eczema, arthritee rhumatoide, maladie de Crohn, sclérosee multiple, maladie du colon irritable, spondylite ankylosante, lupus érythémateux systémique, syndrome de Sjogren, asthme pulmonaire chronique obstructive
Références scientifiques (courts extraits)
Courts extraits uniquement (pas le texte intégral de l’article). Fiches de référence complètes dans l’application Lapo v2.
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Selon Arora L (s.d.)
Extrait The novel herbal composition(s) is useful in the treatment of various disorders, such as psoriasis including plaque psoriasis, gutatte psoriasis, pustular psoriasis & psoriasis of the nails; dermatitis & scleroderma; eczema; inflammatory disorders & other auto-immune diseases like psoriatic arthritis, Rheumatoid arthritis, Crohn's disease, multiple sclerosis, irritable bowel disease, ankylosing spondylitis, systemic lupus erythematosus & Sjogren's syndrome; allergies like asthma & chronic obstructive pulmonary disease & is safe, well-tolerated, non-toxic, with minimal & reversible adverse reactions or side effects, & most Importantly, with minimal relapse or récurrence of the disease following complétion of a treatment regimen. Arora L et al, Herbal composition for treating various disorders including psoriasis, a process for preparation thereof & method for treatment of such disorders-BREVET : 20030194456A1 : The invention provides a novel herbal composition containing the extracts of the leaves and/or stem of Argemone mexicana plant, optionally containing the extracts of the fruits of Cuminum cyminum, which exhibits useful in vitro, in vivo & interesting immunological & pharmacological activities ; a process for preparation thereof & a method of treatment of psoriasis & related immunological & biological disorders by administration of the said novel herbal composition.
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Selon Deshmukh V (2017)
Extrait The aim of present study was to explore the anti-inflammatory activity of ethanolic extract of Argemone mexicana roots on laboratory animals, Wistar rat (180-220g) of either sex. The anti-inflammatory study was done by carrageenan-induced paw edema method.
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Selon Ayele TM (2022)
Extrait The fractions were evaluated at 5 & 10% ointments using moist-exposed burn ointment as the standard drug, & 100, 200, & 400 mg/kg test doses using aspirin, & dexamethasone as standard drugs for wound healing & anti-inflammatory activities, respectively. Conclusion: The results of this study showed that the Ethyl acetate fraction of AM fruit has significant wound healing & anti-inflammatory activities which support the traditional claims of the experimental plant.
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Selon Saraswat I (2025)
Extrait Argemone mexicana, commonly known as the Mexican prickly poppy, has been historically employed in traditional medicine for various ailments, including liver disorders. The botanical composition includes compounds with antioxidant and anti-inflammatory potential, suggesting hepatoprotective effects.
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Selon Ansari KM (2005)
Extrait Since, sanguinarine alkaloid is the major component of Argemone oil, the in vivo DNA damaging potential of the isolated alkaloid was investigated in blood & bone marrow cells of mice using alkaline Comet assay. Consumption of mustard oil contaminated with argemone oil is well known to cause clinical manifestation referred to as "Epidemic Dropsy".
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Selon Arora L (s.d.)
D’autres indications (y compris d’autres modes d’extraction le cas échéant), posologies, précautions d’emploi et les <strong>références scientifiques complètes</strong> (fiches intégrales, pas seulement les courts extraits ci-dessus) sont disponibles dans la fiche monographique de l’application Lapo v2.
Évolution de cette fiche publique
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+18 références · −18 références
Compteurs et domaines uniquement : les libellés d’indications et les noms de synergies ne sont pas publiés ici (ouvrir la fiche dans l’application). Les textes complets des références ajoutées, corrigées ou retirées sont ci-dessous.
+18 références — afficher les textes
Dalvi RR, Sanguinarine: its potential, as a liver toxic alkaloid present in the seeds of Argemone mexicana. Experientia 41 :77-8. 1985.
AjoutéeBhalke R et al. Anti-stress & antiallergic effect of Argemone mexicana stems in asthma. Arch Pharm Sci Res, 1 : 127-9, 2009a-Abstract : Histamine-induced contraction of the guinea pig trachea & precontracted trachea (pathological tissue) [31] h. Isolated organ bath method using guinea pig isolated ileum & tracheal chain [32] Mountain Knot grass Ethanol a [18] Abrus precatorius (Papilionaceae) Love pea Ethanol b,c [27] [28] Ageratum conyzoïdes (Compositae) Billy-goatweed Hydroalcoholic c [26] Asystasia gangetica (Acanthaceae) Chinese violet n-Hexane, ethylacetate, & methanol extracts of the …
AjoutéeBhalke R et al. Phytochemical investigation & effect of various extracts of Argemone mexicana (Papaveraceae) leaves on clonidine & haloperidol-induced catalepsy in mice. J Pharm Res, 2: 765-7, 2009b.-Abstract: Preliminary phytochemical investigation of petroleum ether, chloroform, acetone, methanol & aqueous extract of leaves of Argemone mexicana shows the presence of sterols, flavanoids, tannins, glycosides & alkaloids. These extracts were evaluated for anticataleptic activity. Leaves of A. mexicana were traditionally used as antiasthmatic. For induction of catalepsy, clonidine & haloperid…
AjoutéeKhalid SA. A new chromatographical method for the detection of Argemone mexicana alkaloids in alcoholic drinks native to Sudan. A paper presented to the 34th Inter Congress on Alcoholism & Drug Dependence. Calgary, Alberta, Canada, 1985.
AjoutéeSingh S et al, A new benzylisoquinoline alkaloid from Argemone mexicana. Nat Prod Res, 24 :63-67. 2010b.
AjoutéeSingh S et al, Quaternary alkaloids of Argemone mexicana. Pharm Biol, 48 :158-60. 2010c.
AjoutéeSakthivadivel M et al, Evaluation of toxicity of plant extracts against vector of lymphatic filariasis, Culex quinquefasciatus. Indian J Med Res. 2012; 135 :397-400.-Abstract: Conventional insecticides are generally used as larvicides to control Culex quinquefasciatus, vector of lymphatic filariasis. This study was undertaken to evaluate the larvicidal activity of some potential larvicidal plants leaf extracts against Cx. quinquefasciatus larvae. METHODS: The toxic effects of petroleum ether leaf extracts of plants viz, Argemone mexicana (Mexican prickly poppy), Clausena dentata (Dentate), …
AjoutéeSakthivadivel M et al, Evaluation of toxicity of plant extracts against vector of Lymphatic filariasis, Culex quinquefasciatus. Indian J Med Res 135 :397-400. 2012.
AjoutéeSingh S et al, Antifungal activity of the mixture of quaternary alkaloids isolated from Argemone mexicana against some phytopathogenic fungi. Arch Phyto path ol Plant Prot 43 :769-74. 2010a.
AjoutéeWillcox ML et al, Improved traditional phytomedicines in current use for the clinical treatment of malaria. Planta Med 77 :662-71. 2011.
AjoutéeWillcox ML et al, A reverse pharmacology approach for developing an antimalarial phytomedicine. Malaria J, 10 : S8. Doi :10.1186/1475-2875-10-S1-S8, 2011.
AjoutéeAsuntha G et al, Pharmacological profiling of Argemone mexicana for its aphrodisiac potentials in male Wistar rats, Asian Pac J of Reprod, 2014-Abstract: To study the aphrodisiac potentials of ethanol extract of Argemone mexicana of Papaveraceae family in sexually sluggish male Wistar rats. Methods : The sexually inactive male rats were divided into two groups of 8 rats each. The test group animals were treated with ethanol extract of A. mexicana (EEAM) at 1 g/kg daily oral dose for 28 days. Other group animals were treated with sildénafil citrate at an oral dose of 5 mg/kg. The latencies o…
AjoutéeAsuntha G et al, Effect of Argemone mexicana (L.) against lithium-pilocarpine induced status epilepticus & oxidative stress in Wistar rats, Int J of Exp Biol, 53, 31-5, 2014-Abstract: Argemone mexicana (L.) has a role in the treatment of epileptic disorders in Indian traditional system of medicine. We studied its effect on induced status epilepticus (SE) & oxidative stress in rats. SE was induced in male albino rats by administration of pilocarpine (30 mg/kg, ip) 24 h after injection of lithium chloride (3 mEq/kg, ip). Different doses of the ethanol extract of A. mexicana were administered …
AjoutéeAsuntha G et al, Pharmacological profiling of Argemone mexicana for its aphrodisiac potentials in male Wistar rats, Asian Pac j of Reproduction, 3(2):110-5, 2014-Abstract: To study the aphrodisiac potentials of ethanol extract of Argemone mexicana L. (A. mexicana) of Papaveraceae family in sexually sluggish male Wistar rats. Methods: The sexually inactive male rats were divided into two groups of 8 rats each. The test group animals were treated with ethanol extract of A. mexicana (EEAM) at 1 g/kg daily oral dose for 28 days. Other group animals were treated with sildénafil citrate at an or…
AjoutéeChang YC et al, Two new protopines argemexicaines A & B & the anti-HIV alkaloid 6-acetonyl dihydrochelerythrine from formosan Argemone mexicana. Planta Med 69 :148-52. 2003b.
AjoutéeChang YC et al, Cytotoxic benzophenanthridine & benzylisoquinoline alkaloids from Argemone mexicana. Z Naturforschung 58c :521-6. 2003a-Abstract : Fractionation of the chloroform extract from the aerial part of Argemone mexicana led to the isolation of two benzophenanthridine-type alkaloids, N-demethyloxy-sanguinarine & pancorine ; three benzylisoquinoline-type alkaloids, (+) -1,2,3,4-tetrahydro-1-(2-hydroxymethyl-3,4-dimethoxy-phenyl-methyl) -6,7-methylenedioxyisoquinoline, (+) -higenamine & (+) -réticuline. Among them, N-demethyloxy-sanguinarine is a new compound, & (+) -1,2,3,4- tetrahyd…
AjoutéeSarkar K et al, Phytochemical screening & evaluation of the pharmacological activities of ethanolic extract of Argemone mexicana Linn aerial parts, Oriental Pharm & Experiment Med, 19(4) : 2019-Abstract : The present study was designed to investigate different phytochemical groups present in ethanolic extract of Argemone mexicana aerial parts as well as to assess the analgesic, antidiarrhoeal, antibacterial, anthelmintic & cytotoxic activities of EAMA. Moreover, peripheral & central analgesic activities were evaluated by acetic acid-induced writhing test, formalin-induced paw licking test, …
AjoutéeSarkar K et al, Phytochemical screening & evaluation of the pharmacological activities of ethanolic extract of Argemone mexicana Linn aerial parts, Oriental Pharm & Experiment Med,19(4): 2019-Abstract: The present study was designed to investigate different phytochemical groups present in ethanolic extract of Argemone mexicana aerial parts (EAMA) as well as to assess the analgesic, antidiarrhoeal, antibacterial, anthelmintic & cytotoxic activities of EAMA. Moreover, peripheral & central analgesic activities were evaluated by acetic acid-induced writhing test, formalin-induced paw licking te…
AjoutéeDalvi RR, Sanguinarine: its potential, as a liver toxic alkaloid present in the seeds of Argemone mexicana. Experientia 41 :77-8. 1985.
RetiréeBhalke R et al. Anti-stress & antiallergic effect of Argemone mexicana stems in asthma. Arch Pharm Sci Res, 1 : 127-9, 2009a-Abstract : Histamine-induced contraction of the guinea pig trachea & precontracted trachea (pathological tissue) [31] h. Isolated organ bath method using guinea pig isolated ileum & tracheal chain [32] Mountain Knot grass Ethanol a [18] Abrus precatorius (Papilionaceae) Love pea Ethanol b,c [27] [28] Ageratum conyzoïdes (Compositae) Billy-goatweed Hydroalcoholic c [26] Asystasia gangetica (Acanthaceae) Chinese violet n-Hexane, ethylacetate, & methanol extracts of the …
RetiréeBhalke R et al. Phytochemical investigation & effect of various extracts of Argemone mexicana (Papaveraceae) leaves on clonidine & haloperidol-induced catalepsy in mice. J Pharm Res, 2: 765-7, 2009b.-Abstract: Preliminary phytochemical investigation of petroleum ether, chloroform, acetone, methanol & aqueous extract of leaves of Argemone mexicana shows the presence of sterols, flavanoids, tannins, glycosides & alkaloids. These extracts were evaluated for anticataleptic activity. Leaves of A. mexicana were traditionally used as antiasthmatic. For induction of catalepsy, clonidine & haloperid…
RetiréeKhalid SA. A new chromatographical method for the detection of Argemone mexicana alkaloids in alcoholic drinks native to Sudan. A paper presented to the 34th Inter Congress on Alcoholism & Drug Dependence. Calgary, Alberta, Canada, 1985.
RetiréeSingh S et al, A new benzylisoquinoline alkaloid from Argemone mexicana. Nat Prod Res, 24 :63-67. 2010b.
RetiréeSingh S et al, Quaternary alkaloids of Argemone mexicana. Pharm Biol, 48 :158-60. 2010c.
RetiréeSakthivadivel M et al, Evaluation of toxicity of plant extracts against vector of lymphatic filariasis, Culex quinquefasciatus. Indian J Med Res. 2012; 135 :397-400.-Abstract: Conventional insecticides are generally used as larvicides to control Culex quinquefasciatus, vector of lymphatic filariasis. This study was undertaken to evaluate the larvicidal activity of some potential larvicidal plants leaf extracts against Cx. quinquefasciatus larvae. METHODS: The toxic effects of petroleum ether leaf extracts of plants viz, Argemone mexicana (Mexican prickly poppy), Clausena dentata (Dentate), …
RetiréeSakthivadivel M et al, Evaluation of toxicity of plant extracts against vector of Lymphatic filariasis, Culex quinquefasciatus. Indian J Med Res 135 :397-400. 2012.
RetiréeSingh S et al, Antifungal activity of the mixture of quaternary alkaloids isolated from Argemone mexicana against some phytopathogenic fungi. Arch Phyto path ol Plant Prot 43 :769-74. 2010a.
RetiréeWillcox ML et al, Improved traditional phytomedicines in current use for the clinical treatment of malaria. Planta Med 77 :662-71. 2011.
RetiréeWillcox ML et al, A reverse pharmacology approach for developing an antimalarial phytomedicine. Malaria J, 10 : S8. Doi :10.1186/1475-2875-10-S1-S8, 2011.
RetiréeAsuntha G et al, Pharmacological profiling of Argemone mexicana for its aphrodisiac potentials in male Wistar rats, Asian Pac J of Reprod, 2014-Abstract: To study the aphrodisiac potentials of ethanol extract of Argemone mexicana of Papaveraceae family in sexually sluggish male Wistar rats. Methods : The sexually inactive male rats were divided into two groups of 8 rats each. The test group animals were treated with ethanol extract of A. mexicana (EEAM) at 1 g/kg daily oral dose for 28 days. Other group animals were treated with sildénafil citrate at an oral dose of 5 mg/kg. The latencies o…
RetiréeAsuntha G et al, Effect of Argemone mexicana (L.) against lithium-pilocarpine induced status epilepticus & oxidative stress in Wistar rats, Int J of Exp Biol, 53, 31-5, 2014-Abstract: Argemone mexicana (L.) has a role in the treatment of epileptic disorders in Indian traditional system of medicine. We studied its effect on induced status epilepticus (SE) & oxidative stress in rats. SE was induced in male albino rats by administration of pilocarpine (30 mg/kg, ip) 24 h after injection of lithium chloride (3 mEq/kg, ip). Different doses of the ethanol extract of A. mexicana were administered …
RetiréeAsuntha G et al, Pharmacological profiling of Argemone mexicana for its aphrodisiac potentials in male Wistar rats, Asian Pac j of Reproduction, 3(2):110-5, 2014-Abstract: To study the aphrodisiac potentials of ethanol extract of Argemone mexicana L. (A. mexicana) of Papaveraceae family in sexually sluggish male Wistar rats. Methods: The sexually inactive male rats were divided into two groups of 8 rats each. The test group animals were treated with ethanol extract of A. mexicana (EEAM) at 1 g/kg daily oral dose for 28 days. Other group animals were treated with sildénafil citrate at an or…
RetiréeChang YC et al, Two new protopines argemexicaines A & B & the anti-HIV alkaloid 6-acetonyl dihydrochelerythrine from formosan Argemone mexicana. Planta Med 69 :148-52. 2003b.
RetiréeChang YC et al, Cytotoxic benzophenanthridine & benzylisoquinoline alkaloids from Argemone mexicana. Z Naturforschung 58c :521-6. 2003a-Abstract : Fractionation of the chloroform extract from the aerial part of Argemone mexicana led to the isolation of two benzophenanthridine-type alkaloids, N-demethyloxy-sanguinarine & pancorine ; three benzylisoquinoline-type alkaloids, (+) -1,2,3,4-tetrahydro-1-(2-hydroxymethyl-3,4-dimethoxy-phenyl-methyl) -6,7-methylenedioxyisoquinoline, (+) -higenamine & (+) -réticuline. Among them, N-demethyloxy-sanguinarine is a new compound, & (+) -1,2,3,4- tetrahyd…
RetiréeSarkar K et al, Phytochemical screening & evaluation of the pharmacological activities of ethanolic extract of Argemone mexicana Linn aerial parts, Oriental Pharm & Experiment Med, 19(4) : 2019-Abstract : The present study was designed to investigate different phytochemical groups present in ethanolic extract of Argemone mexicana aerial parts as well as to assess the analgesic, antidiarrhoeal, antibacterial, anthelmintic & cytotoxic activities of EAMA. Moreover, peripheral & central analgesic activities were evaluated by acetic acid-induced writhing test, formalin-induced paw licking test, …
RetiréeSarkar K et al, Phytochemical screening & evaluation of the pharmacological activities of ethanolic extract of Argemone mexicana Linn aerial parts, Oriental Pharm & Experiment Med,19(4): 2019-Abstract: The present study was designed to investigate different phytochemical groups present in ethanolic extract of Argemone mexicana aerial parts (EAMA) as well as to assess the analgesic, antidiarrhoeal, antibacterial, anthelmintic & cytotoxic activities of EAMA. Moreover, peripheral & central analgesic activities were evaluated by acetic acid-induced writhing test, formalin-induced paw licking te…
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