Bixa orellana (Woukou) : vertus médicinales en extraction alcoolique

Bixa orellana (Woukou, Roucou) — famille Bixacées.

Synonymes scientifiques : Bixa acuminata-Bijer, B americana-Poir tinctoria-S, B Orellana americana-Kuntze, Orellana orellana-(l)-Kuntze.

Sources externes reconnues associées à cette monographie : TRAMIL.

Cette base documente les extractions alcooliques (éthanol) des substances actives. Notre monographie recense actuellement 14 indications en extraction alcoolique pour cette espèce. Le catalogue Lapo v2 enregistre 82 références scientifiques pour cette espèce (détail intégral dans l’application).

Important — références scientifiques sur cette page publique : seuls de courts extraits de chaque source citée sont présentés (phrases d’abstract sélectionnées), conservés dans leur langue d’origine (le plus souvent l’anglais), sans traduction. Ces extraits ne constituent pas le texte intégral de l’article ni une bibliographie complète. Les fiches de référence complètes et le détail monographique sont disponibles dans l’application Lapo v2 (essai gratuit 30 jours).

1. 1

   Normalisation des paramètres sériques (AST, ALT)

   Partie usitée : Feuille.

   Références scientifiques (courts extraits)

   Courts extraits uniquement (pas le texte intégral de l’article). Fiches de référence complètes dans l’application Lapo v2.

   • Selon Obidah W (2011)

     Extrait Pretreatment with BO seed oil (10%) resulted in significant (p<0.05) reduction in serum liver marker enzymes activities, total bilirubin concentration, lipid peroxidation & relative liver weights induced by CCl4 administration. The effects of pretreatment with Bixa orellana seed oil on CCl4-induced liver damage were determined in male Wister rats (150±10g).

   • Selon Gatsou Djibersou D (2020)

     Extrait Bixa orellana is a plant from the Bixaceae family, for which, limited information is available on hepatoprotective properties. After treatment, animals were sacrificed, the liver was collected & different biochemical parameters were measured.

   • Selon Lopez CP (2017)

     Extrait This study identified the phytochemicals present in aqueous & ethanolic Bixa orellana leaf extracts & investigated the hepatoprotective activity against carbon tetrachloride (CCl4)-induced hepatotoxicity in mice. Specifically, the study compared serum levels of aspartate aminotransferase (AST) and alanine aminotransferase (ALT) & examined liver tissues histopathology.

   • Selon Valentin SA (2013)

     Extrait The seeds of Bixa orellana are used in popular medicine as a hypolipidemic drug. The animals were treated with the ethanolic & hexane extracts of B orellana.

   • Selon Sales P.F (2023)

     Extrait Moench, Euterpe oleracea Martius & Bixa orellana Linné, have pharmacological activities. The species showed great bioactive activity attributed to their oils, especially in the anti-hypercholesterolemic activity, which can be explained by several pathways of gene expression mechanisms such as the interaction of peroxisome proliferator-activated receptors (PPARs), hepatic X receptors (LXRs), hepatic nuclear factor-4 (HNF4) receptors & sterol regulatory element binding proteins (SREBPs) that act on lipid modulation.

2. 2

   Hépatite, cirrhose, stéatose hépatique

   Partie usitée : Feuille.

   Références scientifiques (courts extraits)

   Courts extraits uniquement (pas le texte intégral de l’article). Fiches de référence complètes dans l’application Lapo v2.

   • Selon Valentin SA (2013)

     Extrait The seeds of Bixa orellana are used in popular medicine as a hypolipidemic drug. The animals were treated with the ethanolic & hexane extracts of B orellana.

   • Selon Lopez CP (2017)

     Extrait This study identified the phytochemicals present in aqueous & ethanolic Bixa orellana leaf extracts & investigated the hepatoprotective activity against carbon tetrachloride (CCl4)-induced hepatotoxicity in mice. Microscopic examination of the liver tissues assessed the extent of hepatic injury.

   • Selon Gatsou Djibersou D (2020)

     Extrait Bixa orellana is a plant from the Bixaceae family, for which, limited information is available on hepatoprotective properties. Conclusion: These results show that infusion from BO barks is hepatoprotective against APAP-induced toxicity via antioxidant & anti-inflammatory mechanism,.

   • Selon Obidah W (2011)

     Extrait The effects of pretreatment with Bixa orellana seed oil on CCl4-induced liver damage were determined in male Wister rats (150±10g). Pretreatment with BO seed oil (10%) resulted in significant (p<0.05) reduction in serum liver marker enzymes activities, total bilirubin concentration, lipid peroxidation & relative liver weights induced by CCl4 administration.

   • Selon Sales P.F (2023)

     Extrait Moench, Euterpe oleracea Martius & Bixa orellana Linné, have pharmacological activities. The species showed great bioactive activity attributed to their oils, especially in the anti-hypercholesterolemic activity, which can be explained by several pathways of gene expression mechanisms such as the interaction of peroxisome proliferator-activated receptors (PPARs), hepatic X receptors (LXRs), hepatic nuclear factor-4 (HNF4) receptors & sterol regulatory element binding proteins (SREBPs) that act on lipid modulation.

3. 3

   Infection bacterienne : Bacillus subtilis, S aureus, Streptococcus faecalis, E coli, Serratia marcescens

   Partie usitée : Feuille.

   Références scientifiques (courts extraits)

   Courts extraits uniquement (pas le texte intégral de l’article). Fiches de référence complètes dans l’application Lapo v2.

   • Selon Mathur A (2010)

     Extrait & Spilanthes americana were evaluated against five bacteria Staphylococcus aureus, Streptococcus hemolytic, Bacillus cereus, Pseudomonas aeruginosa, Escherichia coli & fungus Candida albicans. The antimicrobial activity and minimum inhibitory concentration (MIC) of various plant extracts in different solvents such as ethanol (98%), hexane (99%) and distilled water of plants traditionally used as medicines as Bidens pilosa L., Bixa orellana L., Cecropia peltata L., Cinchona officinalis L., Gliricidia sepium, Jacaranda mimosifolia, Justicia secunda Vahl., Piper pulchrum, P.

   • Selon Rojas JJ (2006)

     Extrait & Spilanthes americana Hiéron were evaluated against five bacteria (Staphylococcus aureus, Streptococcus beta Hemolytic, Bacillus Cereus, Pseudomonas aeruginosa, & Escherichia coli), and one Yeast (Candida albicans). Furthermore, Bixa orellana L, Justicia secunda & Piper pulchrum presented the lowest MICs against Escherichia coli (0.8, 0.6 & 0.6 microg/ml, respectively) compared to Gentamycin sulfate (0.9 8 g/ml).

   • Selon Irobi ON (1996)

     Extrait The extract (5 mg/ml) produced antimicrobial action in agar diffusion assays against standard strains of Gram-positive bacteria including Bacillus subtilis, Staphylococcus aureus, & Streptococcus faecalis while exerting only slight action against Escherichia coli, Serratia marcescens, Candida utilis, & Aspergillus Niger. An organic extract of Annatto (Bixa orellana) leaves obtained in 95% ethanol was examined for in vitro antifungal and antibacterial activity using the agar diffusion and tube dilution methods.

   • Selon Alim S (2016)

     Extrait Methanolic leaf extracts of B orellana were analyzed for their antibacterial activity against pathogenic bacteria including Gram positive bacteria (Bacillus subtilis, Sarcina lutea & Gram-negative bacteria (Escherichia coli, Salmonella typhi, Shigella dysenteriae, Klebsiella pneumonia, Proteus vulgaris) by disc diffusion assay. The aim of this study was to determine the in vitro antibacterial activity of Bixa orellana against some pathogenic bacterial strains & compare with some standard antibiotics.

   • Selon Auteur (2014)

     Extrait Published research studies in animals indicate that various extracts of Bixa leaves exhibit antioxidant, broad antimicrobial (antibacterial and antifungal), anti-inflammatory, analgesic, hypoglycemic, and antidiarrheal activities. Bixa orellana leaf preparations have been used for many years by indigenous people for a variety of medicinal applications.

D’autres indications (y compris d’autres modes d’extraction le cas échéant), posologies, précautions d’emploi et les <strong>références scientifiques complètes</strong> (fiches intégrales, pas seulement les courts extraits ci-dessus) sont disponibles dans la fiche monographique de l’application Lapo v2.