Chenopodium ambrosioides (Simen-kontra) : vertus médicinales en extraction alcoolique

Chenopodium ambrosioides (Simen-kontra, semen-contra, Ansérine, Anserine) — famille Chénopodiacées.

Synonymes scientifiques : Ambrina ambrosioides-(L)-Spach, Atriplex ambosioides-(L)-Crantz, Botrys antihelminthica-(L)-N., Teloxys ambrosioides-(L)-W.A. Weber, Vulvaria ambrosioides-(L)-Bubani.

Sources externes reconnues associées à cette monographie : TRAMIL et Pharmacopée française.

Cette base documente les extractions alcooliques (éthanol) des substances actives. Notre monographie recense actuellement 20 indications en extraction alcoolique pour cette espèce. Le catalogue Lapo v2 enregistre 116 références scientifiques pour cette espèce (détail intégral dans l’application).

Important — références scientifiques sur cette page publique : seuls de courts extraits de chaque source citée sont présentés (phrases d’abstract sélectionnées), conservés dans leur langue d’origine (le plus souvent l’anglais), sans traduction. Ces extraits ne constituent pas le texte intégral de l’article ni une bibliographie complète. Les fiches de référence complètes et le détail monographique sont disponibles dans l’application Lapo v2 (essai gratuit 30 jours).

1. 1

   Diabete mellitus de type II

   Partie usitée : Feuille. Profil pharmacologique documenté : Acarbose-like.

   Références scientifiques (courts extraits)

   Courts extraits uniquement (pas le texte intégral de l’article). Fiches de référence complètes dans l’application Lapo v2.

   • Selon Alhasani R (2024)

     Extrait Our goal in this work was to investigate Chenopodium ambrosioides bioactive profile as well as its in vitro antidiabetic, neuroprotective, & antioxidant properties. Conclusion: These results suggest that based on the antioxidant & enzyme inhibitory potential, CAE could be used as a natural remedy for the treatment of diabetes & neurodegenerative disorders.

   • Selon SONG MJ (2011)

     Extrait mice used in experiment were fed with high-fat diet for two weeks before induction of Diabetes mellitus by injection of streptozocine (STZ). This preliminary but significant study highlighted profound potential of CA to be investigated further for bioactive compounds responsible for antidiabetic effect.

   • Selon KANDSI F (2024)

     Extrait (Chenopodiaceae) is a Moroccan medicinal plant known locally as "M'Khinza." It is widely used in traditional medicine to treat numerous ailments, such as diabetes, digestive disorders, fever, fertility problems, immune disorders, hypertension, bronchitis, respiratory conditions, pharyngitis, cough, & flu. Furthermore, research has also suggested its potential as an anticancer, antidiabetic, & vasorelaxant agent.

2. 2

   Cancer : traitement adjuvant du carcinome d’ascite

   Partie usitée : Feuille.

   Références scientifiques (courts extraits)

   Courts extraits uniquement (pas le texte intégral de l’article). Fiches de référence complètes dans l’application Lapo v2.

   • Selon Nascimento FRF (2006)

     Extrait This inhibition was observed in ascitic tumor cell number, in the ascitic volume, in the tumor-bearing foot size & foot weight when compared to control mice. Ascitic tumor development was evaluated after 8 days of tumor implantation by quantification of the ascitic fluid volume and tumor cell number.

   • Selon Cruz GVB (2007)

     Extrait In conclusion, HCE-treatment was able to increase the macrophages activity & also the cellular recruitment to secondary lymphoid organs, what could explain the previously related antitumor activity of Chenopodium ambrosioïdes. The aim of this study was to investigate the effect of hydroalcoholic crude extract (HCE) from leaves of Chenopodium ambrosioïdes on macrophage activity & on lymphoid organs cellularity.

   • Selon ASSEF ANB (2025)

     Extrait Dysphania ambrosioides, commonly known as "mastruz," is a medicinal plant traditionally used for its therapeutic properties, including antimicrobial & anti-inflammatory effects. However, the lack of selectivity toward tumor cells over normal cells suggests a broad-spectrum cytotoxic activity without tumor-specific therapeutic targeting.

   • Selon ANIFOWOSE LO (2023)

     Extrait Dysphania ambrosioides is an important ingredient of Nigeria's traditional herbal recipe for cancer treatment. Thus, our present study explores its anticancer properties through a structure-based virtual screening of 25 biologically active compounds domiciled in the plant.

   • Selon Heredia-Severino A (1903)

     Extrait Additionally, it has shown antimicrobial, antioxidant, & anticancer properties as it contains compounds that help fight cell damage caused by free radicals. Dysphania ambrosioides, commonly known as epazote, is a medicinal plant of great relevance in traditional Latin American medicine.

3. 3

   Inflammation chronique et dégénérative des articulations: arthrite, arthrose, rhumatisme

   Partie usitée : Parties aériennes.

   Références scientifiques (courts extraits)

   Courts extraits uniquement (pas le texte intégral de l’article). Fiches de référence complètes dans l’application Lapo v2.

   • Selon DEGUENDHARDT RT (2016)

     Extrait The activity of the essential oil of CA is probably related to the large amount of Ascaridol, since the other major compound, p-cymene, is recognized as a potent anti-inflammatory & has low cytotoxic activity. The essential oil of Chenopodium ambrosioïdes was obtained by Steam distillation in a Clevenger apparatus and characterization was performed using chromatographic & spectroscopic assays (GC-FID, GC/MS, 1H NMR).

   • Selon Ibironke GF (2007)

     Extrait A methanol extract of the dried leaves of Chenopodium ambrosioides was investigated for anti-inflammatory and analgesic activities. The extract (300-700 mg kg^-1, p.o.) produced a dose related inhibition of carrageenan-induced paw oedema and cotton pellet-induced granuloma in rats.

   • Selon Grassi LT (2011)

     Extrait Aim of the study : The aim of the present study was to further the understanding of the antinociceptive, anti-inflammatory & wound healing effects of ethanol extract (EE) obtained from the leaves & stems of Chenopodium ambrosioïdes in animal models of acute pain, inflammation & wound healing, thus supporting its medicinal use for the treatment of pain & inflammatory conditions. The anti-inflammatory activity of EE (150–500 mg/kg) was evaluated in carrageenan- (Cg, 300 μg/paw), PGE2- (3 nmol/paw), substance P- (SP, 20 nmol/paw) and BK- (3 nmol/paw) induced paw oedema.

   • Selon KANDSI F (2024)

     Extrait Numerous studies have mentioned the pharmacological properties of DA including its antioxidant, anti-inflammatory, antiparasitic, antiviral, antibacterial, & antifungal activities.

   • Selon ASSEF ANB (2025)

     Extrait Dysphania ambrosioides, commonly known as "mastruz," is a medicinal plant traditionally used for its therapeutic properties, including antimicrobial & anti-inflammatory effects. Future studies should explore additional biological activities, such as anti-inflammatory or immunomodulatory properties, to fully understand the therapeutic applications of DA.

D’autres indications (y compris d’autres modes d’extraction le cas échéant), posologies, précautions d’emploi et les <strong>références scientifiques complètes</strong> (fiches intégrales, pas seulement les courts extraits ci-dessus) sont disponibles dans la fiche monographique de l’application Lapo v2.