Cucurbita pepo (Kourjèt) : vertus médicinales en extraction alcoolique

Cucurbita pepo (Kourjèt, Courgette) — famille Cucurbitacées.

Synonymes scientifiques : Cucurbita aurata-W, C esculenta-N, C fastuosa-S, C melopepo-L, C ovifera-L, C polymorpha-D, Pepo melopepo-(L)-M, P verrucosus-(L)-M, P vulgaris-M.

Sources externes reconnues associées à cette monographie : Pharmacopée française.

Cette base documente les extractions alcooliques (éthanol) des substances actives. Notre monographie recense actuellement 14 indications en extraction alcoolique pour cette espèce. Le catalogue Lapo v2 enregistre 89 références scientifiques pour cette espèce (détail intégral dans l’application).

Important — références scientifiques sur cette page publique : seuls de courts extraits de chaque source citée sont présentés (phrases d’abstract sélectionnées), conservés dans leur langue d’origine (le plus souvent l’anglais), sans traduction. Ces extraits ne constituent pas le texte intégral de l’article ni une bibliographie complète. Les fiches de référence complètes et le détail monographique sont disponibles dans l’application Lapo v2 (essai gratuit 30 jours).

1. 1

   Neuropathie diabétique

   Partie usitée : Semence.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • Selon Kaur N (2023)

     Excerpt The aim of current study was to investigate the potential of CP in attenuation of diabetic neuropathy via using streptozotocin (STZ)-induced diabetes model in male Wistar rats. Conclusion: Thus, CP might ameliorate the progression of diabetic neuropathy via modulation of chronic hyperglycemia & therefore & have therapeutic potential for treatment of diabetic neuropathic pain.

   • Selon Sedigheh A (2011)

     Excerpt This study was aimed to evaluate the hypoglycaemic & hypolipidemic effects of different doses of pumpkin (Cucurbita pepo L.) powder in male diabetic rats. A total of 35 rats were randomized into 5 groups of 7 each as follows: Group 1: Normal control; Group 2: Diabetic control; Group 3: Diabetics administered with low doses of pumpkin powder (1 g/kg); Group 4: Diabetics administered with high doses of pumpkin powder (2 g/kg), and Group 5: Diabetics administered with Glibenclamide (0.6 mg/kg), as positive control.

   • Selon Sahavi M (2018)

     Excerpt (Cucurbita pepo L.) from the Cucurbitaceae family has a low calorie but high nutritional & medical value. Conclusion:

   • Excerpt According to the results we suggest that squash extract could have positive effect on regulating some of blood elements like glucose which are under the bad effect of diabetes type1 in rats.

   • Selon Aboelnaga SM (2017)

     Excerpt In conclusion, pumpkin seed & husk tomato revealed signs of improvement in obese-diabetic rats which might be a good approach to be applied in human suffering from diabetes complication,. The rats in the second group (obese group) were administered with alloxan (120mg alloxan /kg bodyweight) to induce diabetes.

   • Selon Ghahremanloo A (2017)

     Excerpt Cucurbita pepo as a favorable plant has different properties notably antioxidant, lipid-lowering & anti-diabetic potential. Prevention & treatment of obesity is a way to reduce cardiovascular disease, diabetes & depression.

2. 2

   Cancer : traitement adjuvant du carcinome colorectal, hépatique & ovarien

   Partie usitée : Feuille. Profil pharmacologique documenté : Taxus baccata-like, CISPLATINE-like.

   Références scientifiques (courts extraits)

   Courts extraits uniquement (pas le texte intégral de l’article). Fiches de référence complètes dans l’application Lapo v2.

   • Selon Younis YM (2000)

     Extrait Pumpkin (Cucurbita pepo) seeds are used locally in Eritrea to treat tapeworm.

   • Selon Iosypenko OO (s.d.)

     Extrait The qualitative composition & quantitative content of fatty acids in leaves of vegetable marrows (Cucurbita pepo L. giromontina Alef.), zucchini (Cucurbita pepo L.

   • Selon Ghahremanloo A (2017)

     Extrait Cucurbita pepo as a favorable plant has different properties notably antioxidant, lipid-lowering & anti-diabetic potential. Results: CP in a dose-dependent manner dramatically decreased triglycerides & low-density lipoprotein, & liver enzymes while high-density lipoprotein was markedly increased in treated groups.

   • Selon Nkosi CZ (2006)

     Extrait Nkosi CZ et al, In Vitro Antioxidative activity of pumpkin seed (Cucurbita pepo) protein isolate & it’s in vivo effect on alanine transaminase & aspartate transaminase in acetaminophen- induced liver injury in low protein fed rats.

   • Selon Shokrzadeh M (2010)

     Extrait Also, Solanum nigrum has been used as a diuretic & an antipyretic agent & it has also been used to cure inflammation, edema, mastitis & hepatic cancer. nigrum was studied on normal [Chinese hamster ovarian cells (CHO) & rat fibroblast] & cancer (HepG2 & CT26) cell lines.

3. 3

   Stress oxydatif

   Partie usitée : Semence.

   Références scientifiques (courts extraits)

   Courts extraits uniquement (pas le texte intégral de l’article). Fiches de référence complètes dans l’application Lapo v2.

   • Selon NEAMAH GAK (2023)

     Extrait The main goal of the study was to find whether pumpkin (Cucurbita pepo) extract has any preventive or antioxidant properties against acute uranyl acetate (UA)-induced reproductive cytotoxicity. Conclusion: We concluded that UA causes oxidative stress & histopathological alterations in the rat reproductive system.

   • Selon Kaur N (2023)

     Extrait Moreover, the oxidative stress & level of TNF-α, TGF-β & IL-1β was found to be significantly attenuated in experimental animals. Cucurbita pepo is cultivated & used traditionally as vegetable as well as medicine in different parts of the world.

   • Selon Ghahremanloo A (2017)

     Extrait Cucurbita pepo as a favorable plant has different properties notably antioxidant, lipid-lowering & anti-diabetic potential. Conclusions: CP ameliorated oxidative stress & dyslipidemia in obese rats, leading to decrease cardiovascular disease risk in obesity,.

   • Selon El=Sayed G E (2020)

     Extrait In conclusion, results showed that zucchini had similar potential to attenuate CHD-related parameters in a mild oxidative stress induced by high-fat diet in rats.

   • Selon Beshay EVN (2019)

     Extrait However, PZQ was significantly more effective as an antiparasitic agent, whereas PSO was better in terms of fibrosis & oxidative stress. Moreover, the oxidative stress was evaluated by determining the amounts of malondialdehyde & superoxide dismutase in liver homogenates.

D’autres indications (y compris d’autres modes d’extraction le cas échéant), posologies, précautions d’emploi et les <strong>références scientifiques complètes</strong> (fiches intégrales, pas seulement les courts extraits ci-dessus) sont disponibles dans la fiche monographique de l’application Lapo v2.