Amorphophallus campanulatus (Lajan) : medicinal properties in alcoholic extraction

Amorphophallus campanulatus (Lajan, Nèf chimiz, Sèpan, Yanm pié-léfan, Silver, Nine shirts, Snake, elephant-foot yam, Argent, neuf chemises, Serpent, igname-à- pied-d ’éléphant, Nueve camisas, serpiente, ñame de pie de elefante) — family Aracées.

Scientific synonyms : Amorphophallus paenifolius-(Dennst.) -Nico:.

This database documents alcoholic (ethanol) extractions of active substances. Our monograph currently lists 7 indications in alcoholic extraction for this species. The Lapo v2 catalogue records 134 scientific references for this species (full detail in the application).

Important — scientific references on this public page: only a short excerpt of each cited source is shown (selected abstract sentences), kept in the original language of the publication (most often English), without translation. These excerpts are not the full article text and are not a complete bibliography. The full reference records and complete monographic detail are available in the Lapo v2 application (free 30-day trial).

1. 1

   Bacterial infection: Bacillus subtilis, Bacillus megaterium, Staphylococcus aureus, Streptococcus -haemolyticus, Escherichia coli, Shigella dysenteriae, Shigella sonnei, Shigella flexneri, Pseudomonas aeruginosa, Salmonella typhi

   Plant part used: Root (tuber).

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to KHAN A (2008)

     Excerpt Results & Major conclusion: The compound showed significant antibacterial activities against four Gram-positive bacteria (Bacillus subtilis, Bacillus megaterium, Staphylococcus aureus, Streptococcus β-haemolyticus) & six Gram-negative bacteria (Escherichia coli, Shigella dysenteriae, Shigella sonnei, Shigella flexneri, Pseudomonas aeruginosa, Salmonella typhi). Amorphophallus campanulatus is widely distributed in Bangladesh, India, & Africa & the tuberous roots of the plant have many traditional uses & is an important source of biologically active compounds.

   • According to KHAN A (2008)

     Excerpt Results: Large zones of inhibition were observed in disc diffusion antibacterial screening against four Gram-positive bacteria (Bacillus subtilis, Bacillus megaterium, Staphylococcus aureus & Streptococcus pyogenes) & six Gram-negative bacteria (Escherichia coli, Shigella dysenteriae, Shigella sonnei, Shigella flexneri, Pseudomonas aeruginosa & Salmonella typhi). To assess the in vitro antibacterial, antifungal & cytotoxic activities of amblyone, a triterpenoid isolated from Amorphophallus campanulatus (Roxb).

   • According to Kadali VN (2016)

     Excerpt The ethanolic tuber extract of the plant shown inhibitory effect on four bacterial species such as Staphylococcus aureus, Pseudomonas aeruginosa, Escherichia coli & Streptococcus mutans. The ethanolic extract of peel showed inhibitory effect only on two bacterial species such as Staphylococcus aureus & Pseudomonas aeruginosa.

   • According to MUTHUKAMARAN P (2016)

     Excerpt Ethanolic extracts showed the zone of inhibition of 3.75 mm for Staphylococcus aureus MTCC 737 & 4 mm for Pseudomonas aeruginosa MTCC 424. In antibacterial activity, among four extracts, ethyl acetate extract showed maximum activity f or Bacillus subtilis MTCC 121 (7.5 mm zone of inhibition) & Staphylococcus aureus MTCC 737 (7 mm of zone of inhibition).

   • According to Peraman M (2017)

     Excerpt Ethanolic extracts showed the zone of inhibition of 3.75 mm for Staphylococcus aureus - MTCC 737 & methanolic extract showed 4 mm of inhibition for Pseudomonas aeruginosa - MTCC 424.Thus the above studies give basic idea about importance of bioactive compound from these medicinal plants and we can go for further purification & isolation of biologically active molecules from the AP. In antibacterial activity, among four extracts, ethyl acetate extract showed maximum activity for Bacillus subtilis - MTCC 121 (7.5 mm zone of inhibition) & Staphylococcus aureus - MTCC 737 (7 mm of zone of inhibition).

2. 2

   Diarrhoea

   Plant part used: leaf.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to Purwal L (2011)

     Excerpt Hence the present study was under taken to explore anti-diarrhoeal activity of Amorphophallus paenifolius eaves. An array of medicinal plants with anti-diarrhoeal properties has been widely used by the traditional practitioners; however, the efficacy of many of these anti-diarrhoeal conventional medicines has not been scientifically evaluated.

   • According to SHABUDDIN D (2025)

     Excerpt This plant also possesses various health benefits including antibacterial, antioxidant, antitumor, analgesic & antidiarrhoeal due to the presence of phyto-chemicals. Amorphophallus paeoniifolius is one of the potential plants in the genus that has high nutrient content, such as carbohydrates, protein, vitamins & minerals.

   • According to DEY YN (2017)

     Excerpt The tuber of Amorphophallus paeoniifolius (Dennst.) Nicolson (Araceae), commonly called Suran or Jimmikand, has high medicinal value & is used ethnomedicinally for the treatment of different gastrointestinal & inflammatory disorders. In conclusion, the tuber of AP exhibited an anticolitic effect through anti-inflammatory & antioxidant action.

   • According to Arva HR (2012)

     Excerpt In the present study, the effect of the acetone extract of elephant-foot yam (Amorphophallus paeoniifolius (Dennst.) Nicolson) at 0.1 & 0.25% in the diet of streptozotocin-induced male Wistar diabetic rats was studied. The results clearly indicate that the acetone extract of AP is an effective anti-diabetic agent for streptozotocin-induced diabetic rat,.

   • According to Panda J (2025)

     Excerpt Amorphophallus paeoniifolius (elephant foot yam) is an underutilised tropical tuber crop that is commonly grown in South & Southeast Asia. Its phytochemical makeup contains powerful antioxidant, anti-inflammatory, & hypoglycemic capabilities.

3. 3

   Cancer: chemoprevention

   Plant part used: Root (tuber).

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to Ansil PN (2014)

     Excerpt Amorphophallus campanulatus (Roxb.) Blume (family: Araceae) is a tuber crop, largely cultivated throughout the plains of India for using its corm as food. Several possible colon cancer chemopreventive agents are found in edible plants.

   • According to Ansil PN (2014)

     Excerpt In this study, we investigated the curative effect of Amorphophallus campanulatus tuber methanolic extract (ACME) on N-nitrosodiethylamine (NDEA)-induced hepatocellular carcinoma (HCC) in experimental rats. In addition, a standard drug control group was supplemented with silymarin (100 mg/kg bw, orally), a known tumor suppressive agent against HCC.

   • According to ANSIL PN (2013)

     Excerpt This study investigated the effects of Amorphophallus campanulatus tuber methanolic extract (ACME) on aberrant crypt foci (ACF) formation, colonic cell proliferation, lipid peroxidative damage & the antioxidant status in a long-term preclinical model of 1, 2-dimethylhydrazine (DMH) induced colon carcinogenesis in rats. These results indicate that ACME could exert a significant chemopreventive effect on colon carcinogenesis induced by DMH.

   • According to Islam F (2023)

     Excerpt Amorphophallus species are an abundant source of polyphenolic compounds; these are accountable for their pharmacological properties, such as their analgesic, neuroprotective, hepatoprotective, anti-inflammatory, anticonvulsant, antibacterial, antioxidant, anticancer, antiobesity, & immunomodulatory effects, as well as their ability to prevent gastrointestinal disturbance & reduce blood glucose. Moreover, Amorphophallus species contain numerous other classes of chemical compounds, such as alkaloids, steroids, fats and fixed oils, tannins, proteins, and carbohydrates, each of which contributes to the pharmacological effects for the treatment of acute rheumatism, tumors, lung swelling, asthma, vomiting, abdominal pain, & so on.

   • According to Ansil PN (2014)

     Excerpt The aim of the present study was to evaluate the dose-dependent cytotoxic & apoptosis inducing effects of the sub fractions of AC tuber methanolic extract (ACME) namely petroleum ether fraction (PEF), chloroform fraction (CHF), ethyl acetate fraction (EAF) & methanolic fraction (MeF) on human liver cancer cell line, PLC/PRF/5. Amorphophallus campanulatus (Roxb.) Blume belonging to the family of Araceae, is a perennial herb commonly known as elephant foot yam.

Further indications (including other extraction modes where applicable), dosages, precautions for use, and the <strong>full scientific references</strong> (complete records, not only the short excerpts above) are available in the complete monographic record in the Lapo v2 application.