Centella asiatica (Ich-tig) : medicinal properties in alcoholic extraction

Centella asiatica (Ich-tig, Lavéronik, Zèb-poul-bwa, Tiger-child, Véronique, Wood-nettle, Enfant-de-tigre, Herbe-à-poux-de bois, Hijo del tigre, Verónica, Hierba del polen del bosque) — family Apiacées.

Scientific synonyms : Hydrocotyle asiatica-L.

Recognised external sources linked to this monograph: French Pharmacopoeia.

This database documents alcoholic (ethanol) extractions of active substances. Our monograph currently lists 41 indications in alcoholic extraction for this species. The Lapo v2 catalogue records 223 scientific references for this species (full detail in the application).

Important — scientific references on this public page: only a short excerpt of each cited source is shown (selected abstract sentences), kept in the original language of the publication (most often English), without translation. These excerpts are not the full article text and are not a complete bibliography. The full reference records and complete monographic detail are available in the Lapo v2 application (free 30-day trial).

1. 1

   Glibenclamide-induced nephropathy

   Plant part used: Whole plant. Mentioned synergistic association: PLUMERIA RUBRA-L (Fleur), ASPARAGUS RACEMOSUS-Willd.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to Yadav AV (2022)

     Excerpt The current investigation analysed the effect of combination of standardized hydroalcoholic extracts of Asparagus racemosus (AR), Centella asiatica (CA)& Plumeria rubra (PR) on glibenclamide (GB) administered in experimentally induced diabetic nephropathy (DN) in Wistar rats. Co-administration of ACP (400mg/kg) with GB (5mg/kg) significantly (p<0.01) decreased BUN, creatinine, uric acid, significantly increased (p<0.05) SOD, significantly (p<0.01) decreased MDA, significantly increased (p<0.05) serum insulin when compared with diabetic control.

   • According to Venu Gopal Rao ML (2007)

     Excerpt Venu Gopal Rao ML et al Antidiabetic effects of methanolic extract of Centella asiatica (Linn.) on induced hyperglycemic rats.

   • According to Chauhan PK (2010)

     Excerpt The ethanolic & methanolic extracts of the leaves of Centella asiatica (Family-Umbelliferae) were tested for antidiabetic activity, by glucose tolerance test in normal rats and alloxan induced diabetic rats. In long term treatment of alloxan induced diabetic rats, the degree of protection was determined by measuring blood glucose, triglycerides, cholesterol and urea levels on 0, 3, 5, 7 and 10th day.

   • According to Lindawati NY (2014)

     Excerpt The research aims to see the effect of combination from purified extract of AP herb & CA of translocation of GLUT-4 protein in model type 2 diabetes mellitus rats-insulin resistance compared with the use of each purified extract. Determination of insulin resistance used 3 parameters such as blood glucose levels, lipid levels (triglycerides, LDL, cholesterol, & HDL), & hypoglycemic tests with Glibenclamide compared to normal controls animals.

   • According to Wang L (2024)

     Excerpt This study aims to design & develop a PLX/ZnO nanocomposite incorporated with Centella Asiatica extract (CAE) for the multi-functional action in the diabetic wound healing treatment. Diabetic wounds can occur as a prevalent complication among people diagnosed with diabetes, frequently resulting in the necessity for amputation.

2. 2

   Type II diabetes mellitus

   Plant part used: leaf.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to Lindawati NY (2014)

     Excerpt The research aims to see the effect of combination from purified extract of AP herb & CA of translocation of GLUT-4 protein in model type 2 diabetes mellitus rats-insulin resistance compared with the use of each purified extract. Determination of insulin resistance used 3 parameters such as blood glucose levels, lipid levels (triglycerides, LDL, cholesterol, & HDL), & hypoglycemic tests with Glibenclamide compared to normal controls animals.

   • According to Yadav AV (2022)

     Excerpt The current investigation analysed the effect of combination of standardized hydroalcoholic extracts of Asparagus racemosus (AR), Centella asiatica (CA)& Plumeria rubra (PR) on glibenclamide (GB) administered in experimentally induced diabetic nephropathy (DN) in Wistar rats. Co-administration of ACP (400mg/kg) with GB (5mg/kg) significantly (p<0.01) decreased BUN, creatinine, uric acid, significantly increased (p<0.05) SOD, significantly (p<0.01) decreased MDA, significantly increased (p<0.05) serum insulin when compared with diabetic control.

   • According to Chauhan PK (2010)

     Excerpt The ethanolic & methanolic extracts of the leaves of Centella asiatica (Family-Umbelliferae) were tested for antidiabetic activity, by glucose tolerance test in normal rats and alloxan induced diabetic rats. In long term treatment of alloxan induced diabetic rats, the degree of protection was determined by measuring blood glucose, triglycerides, cholesterol and urea levels on 0, 3, 5, 7 and 10th day.

   • According to Wang L (2024)

     Excerpt This study aims to design & develop a PLX/ZnO nanocomposite incorporated with Centella Asiatica extract (CAE) for the multi-functional action in the diabetic wound healing treatment. Diabetic wounds can occur as a prevalent complication among people diagnosed with diabetes, frequently resulting in the necessity for amputation.

   • According to RAALO NNM (2019)

     Excerpt Articles were retrieved from electronic databases such as PubMed & Google Scholar using keywords "Centella asiatica," "asiatic acid," "asiaticoside," "madecassic acid," & "madecassoside." The articles published between 2004 & 2018 that are related to the aforementioned topics were selected. Centella asiatica, a triterpene-rich medicinal herb, is traditionally used to treat various types of diseases including neurological, dermatological, & metabolic diseases.

3. 3

   Type II diabetes mellitus

   Plant part used: aerial parts.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to Yadav AV (2022)

     Excerpt The current investigation analysed the effect of combination of standardized hydroalcoholic extracts of Asparagus racemosus (AR), Centella asiatica (CA)& Plumeria rubra (PR) on glibenclamide (GB) administered in experimentally induced diabetic nephropathy (DN) in Wistar rats. Co-administration of ACP (400mg/kg) with GB (5mg/kg) significantly (p<0.01) decreased BUN, creatinine, uric acid, significantly increased (p<0.05) SOD, significantly (p<0.01) decreased MDA, significantly increased (p<0.05) serum insulin when compared with diabetic control.

   • According to Chauhan PK (2010)

     Excerpt The ethanolic & methanolic extracts of the leaves of Centella asiatica (Family-Umbelliferae) were tested for antidiabetic activity, by glucose tolerance test in normal rats and alloxan induced diabetic rats. In long term treatment of alloxan induced diabetic rats, the degree of protection was determined by measuring blood glucose, triglycerides, cholesterol and urea levels on 0, 3, 5, 7 and 10th day.

   • According to Lindawati NY (2014)

     Excerpt The research aims to see the effect of combination from purified extract of AP herb & CA of translocation of GLUT-4 protein in model type 2 diabetes mellitus rats-insulin resistance compared with the use of each purified extract. f.) Nees.) & Pegagan herb (Centella asiatica (L.) Urban) are excellent medicinal plants which are being developed as traditional for antidiabetic.

   • According to Wang L (2024)

     Excerpt This study aims to design & develop a PLX/ZnO nanocomposite incorporated with Centella Asiatica extract (CAE) for the multi-functional action in the diabetic wound healing treatment. Diabetic wounds can occur as a prevalent complication among people diagnosed with diabetes, frequently resulting in the necessity for amputation.

   • According to RAALO NNM (2019)

     Excerpt Centella asiatica, a triterpene-rich medicinal herb, is traditionally used to treat various types of diseases including neurological, dermatological, & metabolic diseases. Articles were retrieved from electronic databases such as PubMed & Google Scholar using keywords "Centella asiatica," "asiatic acid," "asiaticoside," "madecassic acid," & "madecassoside." The articles published between 2004 & 2018 that are related to the aforementioned topics were selected.

Further indications (including other extraction modes where applicable), dosages, precautions for use, and the <strong>full scientific references</strong> (complete records, not only the short excerpts above) are available in the complete monographic record in the Lapo v2 application.