Centella asiatica (Ich-tig) : vertus médicinales en extraction alcoolique

Centella asiatica (Ich-tig, Lavéronik, Zèb-poul-bwa, Enfant-de-tigre, Véronique, Herbe-à-poux-de bois, Tiger-child, Wood-nettle) — famille Apiacées.

Synonymes scientifiques : Hydrocotyle asiatica-L.

Sources externes reconnues associées à cette monographie : Pharmacopée française.

Cette base documente les extractions alcooliques (éthanol) des substances actives. Notre monographie recense actuellement 40 indications en extraction alcoolique pour cette espèce. Le catalogue Lapo v2 enregistre 224 références scientifiques pour cette espèce (détail intégral dans l’application).

Important — références scientifiques sur cette page publique : seuls de courts extraits de chaque source citée sont présentés (phrases d’abstract sélectionnées), conservés dans leur langue d’origine (le plus souvent l’anglais), sans traduction. Ces extraits ne constituent pas le texte intégral de l’article ni une bibliographie complète. Les fiches de référence complètes et le détail monographique sont disponibles dans l’application Lapo v2 (essai gratuit 30 jours).

1. 1

   Néphropathie induite par Glibenclamide

   Partie usitée : Feuille. Association synergique mentionnée : Plumeria rubra-fleur, ASPARAGUS RACEMOSUS-Willd.

   Références scientifiques (courts extraits)

   Courts extraits uniquement (pas le texte intégral de l’article). Fiches de référence complètes dans l’application Lapo v2.

   • Selon Yadav AV (2022)

     Extrait The current investigation analysed the effect of combination of standardized hydroalcoholic extracts of Asparagus racemosus (AR), Centella asiatica (CA)& Plumeria rubra (PR) on glibenclamide (GB) administered in experimentally induced diabetic nephropathy (DN) in Wistar rats. Co-administration of ACP (400mg/kg) with GB (5mg/kg) significantly (p<0.01) decreased BUN, creatinine, uric acid, significantly increased (p<0.05) SOD, significantly (p<0.01) decreased MDA, significantly increased (p<0.05) serum insulin when compared with diabetic control.

   • Selon Venu Gopal Rao ML (2007)

     Extrait Venu Gopal Rao ML et al Antidiabetic effects of methanolic extract of Centella asiatica (Linn.) on induced hyperglycemic rats.

   • Selon Chauhan PK (2010)

     Extrait The ethanolic & methanolic extracts of the leaves of Centella asiatica (Family-Umbelliferae) were tested for antidiabetic activity, by glucose tolerance test in normal rats and alloxan induced diabetic rats. In long term treatment of alloxan induced diabetic rats, the degree of protection was determined by measuring blood glucose, triglycerides, cholesterol and urea levels on 0, 3, 5, 7 and 10th day.

   • Selon Lindawati NY (2014)

     Extrait The research aims to see the effect of combination from purified extract of AP herb & CA of translocation of GLUT-4 protein in model type 2 diabetes mellitus rats-insulin resistance compared with the use of each purified extract. Determination of insulin resistance used 3 parameters such as blood glucose levels, lipid levels (triglycerides, LDL, cholesterol, & HDL), & hypoglycemic tests with Glibenclamide compared to normal controls animals.

   • Selon Wang L (2024)

     Extrait This study aims to design & develop a PLX/ZnO nanocomposite incorporated with Centella Asiatica extract (CAE) for the multi-functional action in the diabetic wound healing treatment. Diabetic wounds can occur as a prevalent complication among people diagnosed with diabetes, frequently resulting in the necessity for amputation.

2. 2

   Diabete mellitus de type II

   Partie usitée : Feuille. Profil pharmacologique documenté : Glibenclamide-like.

   Références scientifiques (courts extraits)

   Courts extraits uniquement (pas le texte intégral de l’article). Fiches de référence complètes dans l’application Lapo v2.

   • Selon Lindawati NY (2014)

     Extrait The research aims to see the effect of combination from purified extract of AP herb & CA of translocation of GLUT-4 protein in model type 2 diabetes mellitus rats-insulin resistance compared with the use of each purified extract. Determination of insulin resistance used 3 parameters such as blood glucose levels, lipid levels (triglycerides, LDL, cholesterol, & HDL), & hypoglycemic tests with Glibenclamide compared to normal controls animals.

   • Selon Yadav AV (2022)

     Extrait The current investigation analysed the effect of combination of standardized hydroalcoholic extracts of Asparagus racemosus (AR), Centella asiatica (CA)& Plumeria rubra (PR) on glibenclamide (GB) administered in experimentally induced diabetic nephropathy (DN) in Wistar rats. Co-administration of ACP (400mg/kg) with GB (5mg/kg) significantly (p<0.01) decreased BUN, creatinine, uric acid, significantly increased (p<0.05) SOD, significantly (p<0.01) decreased MDA, significantly increased (p<0.05) serum insulin when compared with diabetic control.

   • Selon Chauhan PK (2010)

     Extrait The ethanolic & methanolic extracts of the leaves of Centella asiatica (Family-Umbelliferae) were tested for antidiabetic activity, by glucose tolerance test in normal rats and alloxan induced diabetic rats. In long term treatment of alloxan induced diabetic rats, the degree of protection was determined by measuring blood glucose, triglycerides, cholesterol and urea levels on 0, 3, 5, 7 and 10th day.

   • Selon Wang L (2024)

     Extrait This study aims to design & develop a PLX/ZnO nanocomposite incorporated with Centella Asiatica extract (CAE) for the multi-functional action in the diabetic wound healing treatment. Diabetic wounds can occur as a prevalent complication among people diagnosed with diabetes, frequently resulting in the necessity for amputation.

   • Selon LIU YQ (2022)

     Extrait Diabetic cutaneous ulcers (DCU) are a chronic and refractory complication of diabetes mellitus, which can lead to amputation or even death in extreme cases. Centella asiatica total glycosides are extracted from the traditional Chinese medicine Centella asiatica & have angiogenic, anticancer, antioxidant, &wound healing effects.

3. 3

   Affections hépatiques ; cirrhose, hépatite, stéatose hépatique : Vitis

   Partie usitée : Plante entière.

   Références scientifiques (courts extraits)

   Courts extraits uniquement (pas le texte intégral de l’article). Fiches de référence complètes dans l’application Lapo v2.

   • Selon Munakarmi S (2023)

     Extrait Liver injury can be acute or chronic, resulting from a variety of factors, including viral hepatitis, drug overdose, idiosyncratic drug reaction, or toxins, while the progression of pathogenesis in the liver rises due to the involvement of numerous cytokines & growth factor mediators. Collectively, VCEC exhibited synergistic protective effects against liver injury through its antioxidant, anti-inflammatory, & antiapoptotic ability against oxidative stress, inflammation, & apoptosis.

   • Selon Darnis F (1979)

     Extrait Use of à Titrated extract of Centella asiatica in chronic hepatic disorders.

   • Selon PARK DW (2020)

     Extrait We conducted this study to determine the potential of Centella asiatica as a natural substance to protect against APAP-induced liver injury. However, mice treated with C.A 50% ethanol extract (CA-HE50, 200 mg/kg) for a week before induction of hepatotoxicity by APAP had similar liver weights to those of mice in which hepatotoxicity was not induced.

   • Selon HONG W (2021)

     Extrait In a previous study, we revealed the protective effect of Centella asiatica 50% ethanol extract (CA-HE50) on acetaminophen-induced liver injury. In the present study, we investigate the hepatoprotective effect of CA-HE50 in a lipopolysaccharide /galactosamine (LPS-D-Gal)-induced ALF animal model & compare it to existing therapeutic silymarin, Lentinus edodes mycelia (LEM) extracts, ursodeoxycholic acid (UDCA) & dimethyl diphenyl bicarboxylate (DDB).

   • Selon Ghosh K (2017)

     Extrait The present study was designed to examine the protective effect of Centella asiatica ethanolic leaves extract on the haematological, hepatic & nephritic function marker changes induced in the blood of cadmium chloride treated albino rats. Various concentrations of C asiatica ethanolic extract (20, 40, 60, 80, 100 mg/kg body weight) or silymarin (50 mg/kg body weight) as a pretreatment were administered for 30 days to rats treated with cadmium chloride (5 mg/kg body weight).

D’autres indications (y compris d’autres modes d’extraction le cas échéant), posologies, précautions d’emploi et les <strong>références scientifiques complètes</strong> (fiches intégrales, pas seulement les courts extraits ci-dessus) sont disponibles dans la fiche monographique de l’application Lapo v2.