Cymbopogon shoenanthus (Gran-Sitwonnèl) : medicinal properties in alcoholic extraction

Cymbopogon shoenanthus (Gran-Sitwonnèl, Large lemongrass, Grande citronnelle) — family Poacées.

Scientific synonyms : Andropogon connatus Hochst. Ex A.Rich., A connatus Foliatus-Steud, A schoenanthus L..

This database documents alcoholic (ethanol) extractions of active substances. Our monograph currently lists 7 indications in alcoholic extraction for this species. The Lapo v2 catalogue records 41 scientific references for this species (full detail in the application).

Important — scientific references on this public page: only a short excerpt of each cited source is shown (selected abstract sentences), kept in the original language of the publication (most often English), without translation. These excerpts are not the full article text and are not a complete bibliography. The full reference records and complete monographic detail are available in the Lapo v2 application (free 30-day trial).

1. 1

   Cancer: adjuvant treatment for breast and prostate cancer

   Plant part used: Aerial parts.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to Hakkim FL (2016)

     Excerpt n this study we tested the cytotoxic effect of Oman’s Cymbopogon schoenanthus on breast cancer cells (MDA-MB-231), cervical cancer cells (HEp-2) & Vero cells (normal) and we analyzed their chemical profile by Gas Chromatography Coupled Mass Spectrometry (GCMS). Conclusion: It is clearly evidenced from the results that CS derives active principles specifically targeting tumor cells with very low toxicity on normal cells.

   • According to Author (2020)

     Excerpt nervatus growing in Northern Sudan were examined for their chemical composition, antiproliferative activity against human breast carcinoma & human colon adenocarcinoma cell lines, antioxidant activity (phosphomolybdenum, antiradical, reducing power, & ferrous chelating), & enzyme inhibition activity against acetylcholinesterase butyryl-cholinesterase, tyrosinase, α-glucosidase, and α-amylase. In conclusion, oils from these two Cymbopogon species could be new natural agents with functional properties for food, cosmetics, & pharmaceutical industries.

   • According to Gomes E (2017)

     Excerpt Methods: The chemical characterization of infusions & ethanol: water (50:50, v/v) extracts from Cymbopogon citratus & Cymbopogon schoenanthus was achieved by HPLC-DAD. The aim of this work consisted on expanding the knowledge on the chemical composition of different extracts from Cymbopogon spp., & on the evaluation of their anti-inflammatory potential in cell & cell-free systems.

   • According to Abdoul-Latif MF (2022)

     Excerpt The aim of this research was to evaluate the essential oils of two medicinal plants from Djibouti: Cymbopogon schoenanthus & Nepeta azurea in cytotoxic activity against thirteen (13) cancer cell lines (A2780, A549, HCT116, HEK-293, JIMT-T1, K562, MIA-Paca2, MRC5, NCI-N87, PC3, RT4, U2OS & U87-MG) & antibacterial activity against seven (7) Gram (−) strains (Acinetobacter baumannii, Enterobacter cloacae, Escherichia coli, Klebsiella pneumoniae, Pseudomonas aeruginosa, Salmonella enterica sv. The two essential oils showed inhibitory cytotoxicity activities of all the cancer cells tested; on the other hand, the antibacterial activities are only well-noticed for the CSEO oil at a concentration of 5% against K Pneumoniae, P aeruginosa, Corynebacterium sp., E faecalis & S aureus.

   • According to Hago S (2023)

     Excerpt The extract proved to be highly selective & effective against breast & prostate cancer cell lines (MDA-MB-435, MCF-7, & DU 145) with IC50 as low as 0.7913 ± 0.14, 12.841 ± 0.21, & 30.51 ± 0.18 µg/ml, respectively. aerial part ethanol extract was examined against some cancer cell lines, and HUVEC normal cell lines using MTT assay.

2. 2

   Osteoarthritis, arthritis, rheumatism, oedema

   Plant part used: Sheet.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to Gomes E (2017)

     Excerpt The aim of this work consisted on expanding the knowledge on the chemical composition of different extracts from Cymbopogon spp., & on the evaluation of their anti-inflammatory potential in cell & cell-free systems. Conclusion: This study provided scientific evidence on the ethnopharmacological use of Cymbopogon species on inflammatory conditions, encouraging infusion consumption & future incorporation of Cymbopogon spp.

   • According to Abu-Serie MM (2019)

     Excerpt Methods: The current study recorded a new therapeutic role of the well-known medicinal plants for kidney stones [Ammi visnaga (AVE), Petroselinum crispum (PCE), Hordeum vulgare (HVE), & Cymbopogon schoenanthus (CSE)]. Conclusion: Thus, the studied plant extracts, especially AVE can be considered as promising extracts in the management of nephrotoxicity & other chronic diseases associated with oxidative stress & inflammation.

   • According to Khadri A (2008)

     Excerpt The chemical composition, antioxidant activities & acetylcholinesterase inhibitory properties of the essential oils from fresh leaves, dried leaves & roots collected from three different locations in southern Tunisia, were evaluated. The greatest acetylcholinesterase inhibitory activity (IC50 = 0.26 ± 0.03 mg mL−1) was exhibited by the essential oil of the fresh leaves from the Mountain region.

   • According to Hakkim FL (2016)

     Excerpt n this study we tested the cytotoxic effect of Oman’s Cymbopogon schoenanthus on breast cancer cells (MDA-MB-231), cervical cancer cells (HEp-2) & Vero cells (normal) and we analyzed their chemical profile by Gas Chromatography Coupled Mass Spectrometry (GCMS).

   • According to Hago S (2023)

     Excerpt These findings encourage further in vivo studies to assess the anti-cancer effects of CS extract & its components. The cytotoxic effects of Cymbopogon schoenanthus L.

3. 3

   Pollutant anion-induced nephropathy

   Plant part used: Sheet.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to Abdel-Hamed-Farid (2018)

     Excerpt Conclusions: Both BCAAs & CS or their combined administration afford potential competitors against renal insult-induced by polyvalent anion pollutants in experimentally studied animals model. To better investigate the protective role of branched-chain amino acids (BCAAs) & Cymbopogon schoenanthus ethanolic leaf extract against the potassium dichromate (PDC)-induced oxido nitrosative nephrotoxic insult in the experimental rat model.

   • According to Abu-Serie MM (2019)

     Excerpt Methods: The current study recorded a new therapeutic role of the well-known medicinal plants for kidney stones [Ammi visnaga (AVE), Petroselinum crispum (PCE), Hordeum vulgare (HVE), & Cymbopogon schoenanthus (CSE)]. Consequently, the morphological appearance of Vero cells, cellular necrosis, & the gene expression of kidney injury molecule-1 (a marker of renal injury) after these treatments were improved.

   • According to Gomes E (2017)

     Excerpt Methods: The chemical characterization of infusions & ethanol: water (50:50, v/v) extracts from Cymbopogon citratus & Cymbopogon schoenanthus was achieved by HPLC-DAD. The aim of this work consisted on expanding the knowledge on the chemical composition of different extracts from Cymbopogon spp., & on the evaluation of their anti-inflammatory potential in cell & cell-free systems.

   • According to Al-Ghamdi (2007)

     Excerpt We investigated the effects of Cymbopogon schoenanthus herb on experimental induced kidney stones in male Wistar albino rats. Daily oral treatment with Cymbopogon schoenanthus (1 ml of the extract) significantly corrected the incidence of nephrotoxicity, BUN, creatinine, and calcium level differences.

   • According to El-Bassossy T (2023)

     Excerpt El-Bassossy T et al, Evaluation of the immunomodulatory, antioxidant, & histopathological effects of Cymbopogon schoenanthus essential oil extract on kidney & spleen in BALB/C Mice, Jl of Umm-Al-Qura Univ for Applied Sci, 2023-Abstactract: This study aimed to evaluate the impact of C. The results indicate that high doses of CSEO may increase the levels of some cytokines & antioxidants & have harmful effects on kidney architecture, congested red pulp & fibrosis with increased hematopoiesis.

Further indications (including other extraction modes where applicable), dosages, precautions for use, and the <strong>full scientific references</strong> (complete records, not only the short excerpts above) are available in the complete monographic record in the Lapo v2 application.