Cymbopogon shoenanthus (Gran-Sitwonnèl) : propiedades medicinales en extracción alcohólica

Cymbopogon shoenanthus (Gran-Sitwonnèl, Cimborra grande, Grande citronnelle, Large lemongrass) — familia Poacées.

Sinónimos científicos : Andropogon connatus Hochst. Ex A.Rich., A connatus Foliatus-Steud, A schoenanthus L..

Esta base documenta las extracciones alcohólicas (etanol) de las sustancias activas. Nuestra monografía recoge actualmente 7 indicaciones en extracción alcohólica para esta especie. El catálogo Lapo v2 registra 41 referencias científicas para esta especie (detalle completo en la aplicación).

Indicaciones terapéuticas en extracción alcohólica:

Importante — referencias científicas en esta página pública: solo se muestra un breve extracto de cada fuente citada (frases de resumen seleccionadas), conservado en el idioma original de la publicación (casi siempre el inglés), sin traducir. Estos extractos no constituyen el texto íntegro del artículo ni una bibliografía completa. Las fichas de referencia completas y el detalle monográfico están disponibles en la aplicación Lapo v2 (prueba gratuita de 30 días).

1. 1

   Cáncer: tratamiento adyuvante del carcinoma de mama y de próstata

   Parte usada: partes aéreas.

   Références scientifiques (courts extraits)

   Courts extraits uniquement (pas le texte intégral de l’article). Fiches de référence complètes dans l’application Lapo v2.

   • Selon Hakkim FL (2016)

     Extrait n this study we tested the cytotoxic effect of Oman’s Cymbopogon schoenanthus on breast cancer cells (MDA-MB-231), cervical cancer cells (HEp-2) & Vero cells (normal) and we analyzed their chemical profile by Gas Chromatography Coupled Mass Spectrometry (GCMS). Conclusion: It is clearly evidenced from the results that CS derives active principles specifically targeting tumor cells with very low toxicity on normal cells.

   • Selon Auteur (2020)

     Extrait nervatus growing in Northern Sudan were examined for their chemical composition, antiproliferative activity against human breast carcinoma & human colon adenocarcinoma cell lines, antioxidant activity (phosphomolybdenum, antiradical, reducing power, & ferrous chelating), & enzyme inhibition activity against acetylcholinesterase butyryl-cholinesterase, tyrosinase, α-glucosidase, and α-amylase. In conclusion, oils from these two Cymbopogon species could be new natural agents with functional properties for food, cosmetics, & pharmaceutical industries.

   • Selon Gomes E (2017)

     Extrait Methods: The chemical characterization of infusions & ethanol: water (50:50, v/v) extracts from Cymbopogon citratus & Cymbopogon schoenanthus was achieved by HPLC-DAD. The aim of this work consisted on expanding the knowledge on the chemical composition of different extracts from Cymbopogon spp., & on the evaluation of their anti-inflammatory potential in cell & cell-free systems.

   • Selon Abdoul-Latif MF (2022)

     Extrait The aim of this research was to evaluate the essential oils of two medicinal plants from Djibouti: Cymbopogon schoenanthus & Nepeta azurea in cytotoxic activity against thirteen (13) cancer cell lines (A2780, A549, HCT116, HEK-293, JIMT-T1, K562, MIA-Paca2, MRC5, NCI-N87, PC3, RT4, U2OS & U87-MG) & antibacterial activity against seven (7) Gram (−) strains (Acinetobacter baumannii, Enterobacter cloacae, Escherichia coli, Klebsiella pneumoniae, Pseudomonas aeruginosa, Salmonella enterica sv. The two essential oils showed inhibitory cytotoxicity activities of all the cancer cells tested; on the other hand, the antibacterial activities are only well-noticed for the CSEO oil at a concentration of 5% against K Pneumoniae, P aeruginosa, Corynebacterium sp., E faecalis & S aureus.

   • Selon Hago S (2023)

     Extrait The extract proved to be highly selective & effective against breast & prostate cancer cell lines (MDA-MB-435, MCF-7, & DU 145) with IC50 as low as 0.7913 ± 0.14, 12.841 ± 0.21, & 30.51 ± 0.18 µg/ml, respectively. In silico modeling was performed to investigate the binding orientation & affinity of the major identified compounds against Polo-like kinase (PLK1 protein) a cancer molecular target using molecular docking & molecular dynamic whereas eudesm-5-en-11-ol, piperitone, & 2,3-dihydrobenzofuran displayed better binding affinity & stability against PLK1 compared to the reference drug.

2. 2

   Artrosis, artritis, reumatismo, edema

   Parte usada: Hoja.

   Références scientifiques (courts extraits)

   Courts extraits uniquement (pas le texte intégral de l’article). Fiches de référence complètes dans l’application Lapo v2.

   • Selon Gomes E (2017)

     Extrait The aim of this work consisted on expanding the knowledge on the chemical composition of different extracts from Cymbopogon spp., & on the evaluation of their anti-inflammatory potential in cell & cell-free systems. Conclusion: This study provided scientific evidence on the ethnopharmacological use of Cymbopogon species on inflammatory conditions, encouraging infusion consumption & future incorporation of Cymbopogon spp.

   • Selon Abu-Serie MM (2019)

     Extrait Methods: The current study recorded a new therapeutic role of the well-known medicinal plants for kidney stones [Ammi visnaga (AVE), Petroselinum crispum (PCE), Hordeum vulgare (HVE), & Cymbopogon schoenanthus (CSE)]. Conclusion: Thus, the studied plant extracts, especially AVE can be considered as promising extracts in the management of nephrotoxicity & other chronic diseases associated with oxidative stress & inflammation.

   • Selon Khadri A (2008)

     Extrait The chemical composition, antioxidant activities & acetylcholinesterase inhibitory properties of the essential oils from fresh leaves, dried leaves & roots collected from three different locations in southern Tunisia, were evaluated. The greatest acetylcholinesterase inhibitory activity (IC50 = 0.26 ± 0.03 mg mL−1) was exhibited by the essential oil of the fresh leaves from the Mountain region.

   • Selon Hakkim FL (2016)

     Extrait n this study we tested the cytotoxic effect of Oman’s Cymbopogon schoenanthus on breast cancer cells (MDA-MB-231), cervical cancer cells (HEp-2) & Vero cells (normal) and we analyzed their chemical profile by Gas Chromatography Coupled Mass Spectrometry (GCMS).

   • Selon Hago S (2023)

     Extrait These findings encourage further in vivo studies to assess the anti-cancer effects of CS extract & its components. The cytotoxic effects of Cymbopogon schoenanthus L.

3. 3

   Nefropatía inducida por aniones contaminantes

   Parte usada: Hoja.

   Références scientifiques (courts extraits)

   Courts extraits uniquement (pas le texte intégral de l’article). Fiches de référence complètes dans l’application Lapo v2.

   • Selon Abdel-Hamed-Farid (2018)

     Extrait Conclusions: Both BCAAs & CS or their combined administration afford potential competitors against renal insult-induced by polyvalent anion pollutants in experimentally studied animals model. To better investigate the protective role of branched-chain amino acids (BCAAs) & Cymbopogon schoenanthus ethanolic leaf extract against the potassium dichromate (PDC)-induced oxido nitrosative nephrotoxic insult in the experimental rat model.

   • Selon Abu-Serie MM (2019)

     Extrait Methods: The current study recorded a new therapeutic role of the well-known medicinal plants for kidney stones [Ammi visnaga (AVE), Petroselinum crispum (PCE), Hordeum vulgare (HVE), & Cymbopogon schoenanthus (CSE)]. Consequently, the morphological appearance of Vero cells, cellular necrosis, & the gene expression of kidney injury molecule-1 (a marker of renal injury) after these treatments were improved.

   • Selon Gomes E (2017)

     Extrait Methods: The chemical characterization of infusions & ethanol: water (50:50, v/v) extracts from Cymbopogon citratus & Cymbopogon schoenanthus was achieved by HPLC-DAD. The aim of this work consisted on expanding the knowledge on the chemical composition of different extracts from Cymbopogon spp., & on the evaluation of their anti-inflammatory potential in cell & cell-free systems.

   • Selon Al-Ghamdi (2007)

     Extrait We investigated the effects of Cymbopogon schoenanthus herb on experimental induced kidney stones in male Wistar albino rats. Daily oral treatment with Cymbopogon schoenanthus (1 ml of the extract) significantly corrected the incidence of nephrotoxicity, BUN, creatinine, and calcium level differences.

   • Selon El-Bassossy T (2023)

     Extrait El-Bassossy T et al, Evaluation of the immunomodulatory, antioxidant, & histopathological effects of Cymbopogon schoenanthus essential oil extract on kidney & spleen in BALB/C Mice, Jl of Umm-Al-Qura Univ for Applied Sci, 2023-Abstactract: This study aimed to evaluate the impact of C. The results indicate that high doses of CSEO may increase the levels of some cytokines & antioxidants & have harmful effects on kidney architecture, congested red pulp & fibrosis with increased hematopoiesis.

Otras indicaciones (incluidos otros modos de extracción si procede), posologías, precauciones de uso y las <strong>referencias científicas completas</strong> (fichas íntegras, no solo los extractos cortos anteriores) están disponibles en la ficha monográfica de la aplicación Lapo v2.