Cymbopogon shoenanthus (Gran-Sitwonnèl) : vertus médicinales en extraction alcoolique

Cymbopogon shoenanthus (Gran-Sitwonnèl, Grande citronnelle, Large lemongrass) — famille Poacées.

Synonymes scientifiques : Andropogon connatus Hochst. Ex A.Rich., A connatus Foliatus-Steud, A schoenanthus L..

Cette base documente les extractions alcooliques (éthanol) des substances actives. Notre monographie recense actuellement 7 indications en extraction alcoolique pour cette espèce. Le catalogue Lapo v2 enregistre 41 références scientifiques pour cette espèce (détail intégral dans l’application).

Important — références scientifiques sur cette page publique : seuls de courts extraits de chaque source citée sont présentés (phrases d’abstract sélectionnées), conservés dans leur langue d’origine (le plus souvent l’anglais), sans traduction. Ces extraits ne constituent pas le texte intégral de l’article ni une bibliographie complète. Les fiches de référence complètes et le détail monographique sont disponibles dans l’application Lapo v2 (essai gratuit 30 jours).

1. 1

   Cancer : traitement adjuvant du carcinome mammaire & prostatique

   Partie usitée : Parties aeriennes.

   Références scientifiques (courts extraits)

   Courts extraits uniquement (pas le texte intégral de l’article). Fiches de référence complètes dans l’application Lapo v2.

   • Selon Hakkim FL (2016)

     Extrait n this study we tested the cytotoxic effect of Oman’s Cymbopogon schoenanthus on breast cancer cells (MDA-MB-231), cervical cancer cells (HEp-2) & Vero cells (normal) and we analyzed their chemical profile by Gas Chromatography Coupled Mass Spectrometry (GCMS). Conclusion: It is clearly evidenced from the results that CS derives active principles specifically targeting tumor cells with very low toxicity on normal cells.

   • Selon Auteur (2020)

     Extrait nervatus growing in Northern Sudan were examined for their chemical composition, antiproliferative activity against human breast carcinoma & human colon adenocarcinoma cell lines, antioxidant activity (phosphomolybdenum, antiradical, reducing power, & ferrous chelating), & enzyme inhibition activity against acetylcholinesterase butyryl-cholinesterase, tyrosinase, α-glucosidase, and α-amylase. In conclusion, oils from these two Cymbopogon species could be new natural agents with functional properties for food, cosmetics, & pharmaceutical industries.

   • Selon Gomes E (2017)

     Extrait Methods: The chemical characterization of infusions & ethanol: water (50:50, v/v) extracts from Cymbopogon citratus & Cymbopogon schoenanthus was achieved by HPLC-DAD. The aim of this work consisted on expanding the knowledge on the chemical composition of different extracts from Cymbopogon spp., & on the evaluation of their anti-inflammatory potential in cell & cell-free systems.

   • Selon Abdoul-Latif MF (2022)

     Extrait The aim of this research was to evaluate the essential oils of two medicinal plants from Djibouti: Cymbopogon schoenanthus & Nepeta azurea in cytotoxic activity against thirteen (13) cancer cell lines (A2780, A549, HCT116, HEK-293, JIMT-T1, K562, MIA-Paca2, MRC5, NCI-N87, PC3, RT4, U2OS & U87-MG) & antibacterial activity against seven (7) Gram (−) strains (Acinetobacter baumannii, Enterobacter cloacae, Escherichia coli, Klebsiella pneumoniae, Pseudomonas aeruginosa, Salmonella enterica sv. The two essential oils showed inhibitory cytotoxicity activities of all the cancer cells tested; on the other hand, the antibacterial activities are only well-noticed for the CSEO oil at a concentration of 5% against K Pneumoniae, P aeruginosa, Corynebacterium sp., E faecalis & S aureus.

   • Selon Hago S (2023)

     Extrait The extract proved to be highly selective & effective against breast & prostate cancer cell lines (MDA-MB-435, MCF-7, & DU 145) with IC50 as low as 0.7913 ± 0.14, 12.841 ± 0.21, & 30.51 ± 0.18 µg/ml, respectively. In silico modeling was performed to investigate the binding orientation & affinity of the major identified compounds against Polo-like kinase (PLK1 protein) a cancer molecular target using molecular docking & molecular dynamic whereas eudesm-5-en-11-ol, piperitone, & 2,3-dihydrobenzofuran displayed better binding affinity & stability against PLK1 compared to the reference drug.

2. 2

   Arthrose, arthrite, rhumatisme, oedème

   Partie usitée : Feuille.

   Références scientifiques (courts extraits)

   Courts extraits uniquement (pas le texte intégral de l’article). Fiches de référence complètes dans l’application Lapo v2.

   • Selon Gomes E (2017)

     Extrait The aim of this work consisted on expanding the knowledge on the chemical composition of different extracts from Cymbopogon spp., & on the evaluation of their anti-inflammatory potential in cell & cell-free systems. Conclusion: This study provided scientific evidence on the ethnopharmacological use of Cymbopogon species on inflammatory conditions, encouraging infusion consumption & future incorporation of Cymbopogon spp.

   • Selon Abu-Serie MM (2019)

     Extrait Methods: The current study recorded a new therapeutic role of the well-known medicinal plants for kidney stones [Ammi visnaga (AVE), Petroselinum crispum (PCE), Hordeum vulgare (HVE), & Cymbopogon schoenanthus (CSE)]. Conclusion: Thus, the studied plant extracts, especially AVE can be considered as promising extracts in the management of nephrotoxicity & other chronic diseases associated with oxidative stress & inflammation.

   • Selon Khadri A (2008)

     Extrait The chemical composition, antioxidant activities & acetylcholinesterase inhibitory properties of the essential oils from fresh leaves, dried leaves & roots collected from three different locations in southern Tunisia, were evaluated. The greatest acetylcholinesterase inhibitory activity (IC50 = 0.26 ± 0.03 mg mL−1) was exhibited by the essential oil of the fresh leaves from the Mountain region.

   • Selon Hakkim FL (2016)

     Extrait n this study we tested the cytotoxic effect of Oman’s Cymbopogon schoenanthus on breast cancer cells (MDA-MB-231), cervical cancer cells (HEp-2) & Vero cells (normal) and we analyzed their chemical profile by Gas Chromatography Coupled Mass Spectrometry (GCMS).

   • Selon Hago S (2023)

     Extrait These findings encourage further in vivo studies to assess the anti-cancer effects of CS extract & its components. The cytotoxic effects of Cymbopogon schoenanthus L.

3. 3

   Renopathie induite par anion polluant

   Partie usitée : Feuille.

   Références scientifiques (courts extraits)

   Courts extraits uniquement (pas le texte intégral de l’article). Fiches de référence complètes dans l’application Lapo v2.

   • Selon Abdel-Hamed-Farid (2018)

     Extrait Conclusions: Both BCAAs & CS or their combined administration afford potential competitors against renal insult-induced by polyvalent anion pollutants in experimentally studied animals model. To better investigate the protective role of branched-chain amino acids (BCAAs) & Cymbopogon schoenanthus ethanolic leaf extract against the potassium dichromate (PDC)-induced oxido nitrosative nephrotoxic insult in the experimental rat model.

   • Selon Abu-Serie MM (2019)

     Extrait Methods: The current study recorded a new therapeutic role of the well-known medicinal plants for kidney stones [Ammi visnaga (AVE), Petroselinum crispum (PCE), Hordeum vulgare (HVE), & Cymbopogon schoenanthus (CSE)]. Consequently, the morphological appearance of Vero cells, cellular necrosis, & the gene expression of kidney injury molecule-1 (a marker of renal injury) after these treatments were improved.

   • Selon Gomes E (2017)

     Extrait Methods: The chemical characterization of infusions & ethanol: water (50:50, v/v) extracts from Cymbopogon citratus & Cymbopogon schoenanthus was achieved by HPLC-DAD. The aim of this work consisted on expanding the knowledge on the chemical composition of different extracts from Cymbopogon spp., & on the evaluation of their anti-inflammatory potential in cell & cell-free systems.

   • Selon Al-Ghamdi (2007)

     Extrait We investigated the effects of Cymbopogon schoenanthus herb on experimental induced kidney stones in male Wistar albino rats. Daily oral treatment with Cymbopogon schoenanthus (1 ml of the extract) significantly corrected the incidence of nephrotoxicity, BUN, creatinine, and calcium level differences.

   • Selon El-Bassossy T (2023)

     Extrait El-Bassossy T et al, Evaluation of the immunomodulatory, antioxidant, & histopathological effects of Cymbopogon schoenanthus essential oil extract on kidney & spleen in BALB/C Mice, Jl of Umm-Al-Qura Univ for Applied Sci, 2023-Abstactract: This study aimed to evaluate the impact of C. The results indicate that high doses of CSEO may increase the levels of some cytokines & antioxidants & have harmful effects on kidney architecture, congested red pulp & fibrosis with increased hematopoiesis.

D’autres indications (y compris d’autres modes d’extraction le cas échéant), posologies, précautions d’emploi et les <strong>références scientifiques complètes</strong> (fiches intégrales, pas seulement les courts extraits ci-dessus) sont disponibles dans la fiche monographique de l’application Lapo v2.